L-Lactide homopolymer

Product Information

Molecular Formula:
(C6H8O4)x
Molecular Weight:
144.12
Description
Lactide is a member of dioxanes.
Synonyms
1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)-, homopolymer; 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S-cis)-, homopolymer; p-Dioxane-2,5-dione, 3,6-dimethyl-, (S,S)-, polyesters; Poly-L-lactide; L-Lactide polymer
IUPAC Name
3,6-dimethyl-1,4-dioxane-2,5-dione
Canonical SMILES
CC1C(=O)OC(C(=O)O1)C
InChI
InChI=1S/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3/t3-,4-/m0/s1
InChI Key
JJTUDXZGHPGLLC-IMJSIDKUSA-N
Boiling Point
285.5ºC at 760 mmHg
Melting Point
153 °C
Flash Point
150.6ºC
Purity
95%
Density
1.27 g/cm3
Application
Used to make polylactic acid and cosmetics.
Storage
-20ºC
Refractive Index
1.429
Tg
60-65°C
LogP
-0.13660

Safety Information

Hazards
Harmless-use normal precautions. Hygroscopic
Handling
Exercise normal care
Molecular WeightViscosityDescription
Mw~700,000 5.70 - 8.20 dL/g (25°C; CHCl3. 0.1 g/dL) Poly(L-lactide) (PLLA) is a biodegradable polymer for medical device and pharmaceutical applications. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices.
Mw~1,600-2,400 0.10 - 0.20 dL/g (25°C; CHCl3. 1.0 g/dL) Poly(L-lactide) (PLLA) is a biodegradable polymer for medical device and pharmaceutical applications. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices.
Mw~80,000-100,000 1.50 - 2.00 dL/g (25°C; CHCl3. 0.1 g/dL) Poly(L-lactide) (PLLA) is a biodegradable polymer for medical device and pharmaceutical applications. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices.
Mw 40,000~70,000 0.90 - 1.20 dL/g (25°C; CHCl3. 0.1 g/dL) Poly(L-lactide) (PLLA) is a biodegradable polymer for medical device and pharmaceutical applications. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices.
Mw~325,000-460,000 4.3 - 5.5 dL/g (25°C; CHCl3l. 0.1 g/dL) Poly(L-lactide) (PLLA) is a biodegradable polymer for medical device and pharmaceutical applications. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices.

Computed Properties

XLogP3
0.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
144.04225873 g/mol
Monoisotopic Mass
144.04225873 g/mol
Topological Polar Surface Area
52.6Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
155
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
US-2021188799-A1 Synthesis method and device for rapidly producing lactide at high yield 2021-03-04
US-10959969-B1 Methods of treating SARS Cov-2 virus with protocatechuic acid 2020-07-24
US-2021186491-A1 Suture packages having integrated suture straightening assemblies 2019-12-24
EP-3839043-A1 Screening methods for compounds modulating polyamine transport 2019-12-20
WO-2021121412-A1 Leadless pacemaker and tail end component and head end component thereof 2019-12-20
WO-2021123655-A1 Method for manufacturing a polyester containing at least one 1,4:3,6-dianhydrohexitol unit with reduced colouring and improved rates of incorporation of the unit(s) 2019-12-20
WO-2021124301-A1 Formulations and method for treatment of inflammatory diseases 2019-12-20
WO-2021125236-A1 Biaxially oriented polyester film and method for producing same 2019-12-20
EP-3838976-A1 Process for degrading plastic products 2019-12-19
WO-2021119727-A1 Biocompatible material 2019-12-19

Literatures

PMID Publication Date Title Journal
22088756 2012-11-01 Poly (N-isopropylacrylamide)-PLA and PLA blend nanoparticles for temperature-controllable drug release and intracellular uptake Colloids and surfaces. B, Biointerfaces
22961054 2012-10-28 Alkaline earth metal complexes of a chiral polyether as initiator for the ring-opening polymerization of lactide Dalton transactions (Cambridge, England : 2003)
22968601 2012-10-25 Nacnac(Bn)CuOiPr: a strained geometry resulting in very high lactide polymerization activity Chemical communications (Cambridge, England)
23016983 2012-10-24 Tandem metal-coordination copolymerization and organocatalytic ring-opening polymerization via water to synthesize diblock copolymers of styrene oxide/CO2 and lactide Journal of the American Chemical Society
23009063 2012-10-15 Stereoselective synthesis of biphenolate/binaphtolate titanate and zirconate alkoxide species: structural characterization and use in the controlled ROP of lactide Inorganic chemistry
23030249 2012-10-15 Synthesis and characterization of amine-bridged bis(phenolate)lanthanide alkoxides and their application in the controlled polymerization of rac-lactide and rac-β-butyrolactone Inorganic chemistry
22903466 2012-10-14 Dimethylaluminium aldiminophenolates: synthesis, characterization and ring-opening polymerization behavior towards lactides Dalton transactions (Cambridge, England : 2003)
22561339 2012-10-10 Dual-purpose magnetic micelles for MRI and gene delivery Journal of controlled release : official journal of the Controlled Release Society
22930321 2012-10-09 Highly heteroselective ring-opening polymerization of racemic lactide initiated by divalent ytterbium complexes bearing amino bis(phenolate) ligands Chemical communications (Cambridge, England)
22892614 2012-10-07 Al and Zn complexes bearing N,N,N-tridentate quinolinyl anilido-imine ligands: synthesis, characterization and catalysis in L-lactide polymerization Dalton transactions (Cambridge, England : 2003)
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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