1,4-Dihydroxynaphthalene

Product Information

Molecular Formula:
C10H8O2
Molecular Weight:
160.17
Description
1,4-Dihydroxynaphthalene (CAS# 571-60-8) is a useful research chemical.
Synonyms
naphthalene-1,4-diol
IUPAC Name
naphthalene-1,4-diol
Canonical SMILES
C1=CC=C2C(=C1)C(=CC=C2O)O
InChI
InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H
InChI Key
PCILLCXFKWDRMK-UHFFFAOYSA-N
Boiling Point
391 °C at 760 mmHg
Melting Point
188-192 °C
Purity
Techincal grade
Density
1.33 g/cm3
Appearance
Brown to greyish powder
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Refractive Index
1.5178 (estimate)
LogP
2.25100

Safety Information

Hazards
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H318:
Causes serious eye damage.
Precautionary Statement
P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501
Signal Word
Danger

QC Data

Computed Properties

XLogP3
1.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
160.052429494 g/mol
Monoisotopic Mass
160.052429494 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
140
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114133497-A Water-based polymer emulsion and preparation method and application thereof 2021-11-26
CN-113845775-A Preparation method of hyperbranched polymer modified boron nitride heat-conducting and insulating composite material 2021-11-08
CN-113637153-A Multi-block polyether type high-molecular surfactant and preparation method and application thereof 2021-10-18
CN-113637154-A Nonionic polyether type high-molecular surfactant and preparation method and application thereof 2021-10-18
CN-113637155-A Anionic polyether type high-molecular surfactant and preparation method thereof 2021-10-18
CN-113880977-A Olefin polymerization catalyst, preparation method and application 2021-10-18
CN-113773484-A Preparation method of mining polyether polyol with high compressive strength 2021-09-10
CN-113461932-A Preparation method of polyaryletherketone 2021-07-29
CN-113527660-A Preparation of artificial fungus black material and antioxidation application 2021-07-09
CN-113683771-A Preparation of artificial fungus black material and application of ultraviolet protection 2021-07-09

Literatures

PMID Publication Date Title Journal
22682920 2012-07-15 A laccase-catalysed one-pot synthesis of aminonaphthoquinones and their anticancer activity Bioorganic & medicinal chemistry
22530964 2012-05-18 Three different dimerizations of 2-bromo-3-methyl-1,4-naphthoquinones The Journal of organic chemistry
22220566 2012-03-08 Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors Journal of medicinal chemistry
20055453 2010-02-11 Rational design of indoleamine 2,3-dioxygenase inhibitors Journal of medicinal chemistry
20127150 2010-02-01 Naphthoquinones and anthraquinones from scent glands of a dyspnoid Harvestman, Paranemastoma quadripunctatum Journal of chemical ecology
19938843 2009-12-18 N-Heterocyclic carbene-catalyzed monoacylation of 1,4-naphthoquinones with aldehydes The Journal of organic chemistry
19893237 2009-11-01 5-Amino-1-naphthol: two-dimensional sheets built up from R(4)(4)(18) rings formed by O-H...N, N-H...O and pi-pi interactions Acta crystallographica. Section C, Crystal structure communications
19753562 2009-10-01 Synthesis and cytotoxic evaluation of 6-(3-pyrazolylpropyl) derivatives of 1,4-naphthohydroquinone-1,4-diacetate Archiv der Pharmazie
19338340 2009-04-01 Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress Chemical research in toxicology
18708272 2009-03-01 2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents European journal of medicinal chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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