Nitroxide-mediated polymerization (NMP) is a controlled/living radical polymerization (CLRP) technique and enables the design of well-defined, functional, and complex macromolecular architectures. BOC Sciences provides our global customers with the most competitive polymer products and customized polymer synthesis services. We can support and guide you in developing a testable candidate matrix and defining the ideal polymer products for you.
Synthetic polymers are now considered an essential part of varied objects and materials in our everyday life. Nitroxide-mediated polymerization (NMP) is a reversible-deactivation radical polymerization (RDRP) technique synthesizes well-defined and complex macromolecular architectures with low polymer dispersity and high chain-end homogeneity. NMP is an inherently simple and industrially robust technique that often requires a single unimolecular initiator with a monomer to polymerize, followed by a simple precipitation/filtration to afford final products. Unlike other RDRP techniques, NMP provides clean, well-defined polymers without transition metal complexes, favorable for sensitive biological and electronic applications.
Fig. 1. Examples of nitroxide-mediated polymerization (NMP) applications (ACS Appl. Polym. Mater. 2020, 2, 12, 5327-5344).
Historically, nitroxide-mediated polymerization (NMP) is the first widespread controlled radical polymerization method. In the NMP process, nitroxide derivatives control polymerization. Mechanistically, persistent aminoxyl radicals couple reversibly at high temperatures with macroradicals (i.e., growing polymer chains), leading to an equilibrium between a small fraction of active chains and a large fraction of inactive chains (a.k.a dormant chains) capped by an alkoxyamine moiety. Consequently, NMPs exhibit a controlled/living behavior and therefore allow wide possibilities of macromolecular engineering.
The nitroxide-mediated polymerization (NMP) process is based on the reversible activation and deactivation of a stable free radical that facilitates the controlled, pseudo-living polymerization of a propagating chain with a given monomer. Based on the scale-up potential of NMP, BOC Sciences' researchers enable the production of highly defined polymer architectures without air-free transfers, transition metal catalysts, or problematic thiol agents. Our NMP polymerization products do not require additional purification of final polymers before being used for sensitive electronic or biological applications. Our experienced R&D teams, advanced technology platforms, and trustworthy quality will resolve your research challenges.
BOC Sciences can provide a wide variety of raw materials from upstream lines for automotive parts manufacturing, such as monomers, polymers and additives.
BOC Sciences supplies the necessary raw materials to help you manufacture ideal composites.
BOC Sciences can help our customers further understand the functionality and applicable requirements for raw materials in different healthcare segments.
BOC Sciences' seasoned experts can help you from upstream lines to arrive at the most appropriate solution to improve production and optimize your bottom line.