Polymer Reprecipitation Services

Polymer precipitation services form BOC Sciences are available for the production of custom-designed polymer particles for specific applications. Our services offer a range of polymer precipitation methods and can produce particles of various sizes and morphologies, depending on the application requirements. Some common applications of our polymer particles produced through precipitation include drug delivery systems, coatings, and pigments.

What is Polymer Precipitation?

Polymer precipitation is a widely used method for the production of polymers in various forms, such as powders, microspheres, and nanoparticles. This process involves the separation of dissolved polymer molecules from a solvent by the addition of a nonsolvent. The addition of the nonsolvent reduces the solubility of the polymer, leading to its precipitation as solid particles. Polymer precipitation methods can be broadly categorized into two main types: homogeneous and heterogeneous precipitation. In homogeneous precipitation, the solvent and nonsolvent are miscible, and the polymer precipitates uniformly throughout the solution. Heterogeneous precipitation, on the other hand, involves the addition of a nonsolvent that is immiscible with the solvent, leading to the formation of polymer particles at the interface between the two phases.

Steps of MIPSE methodsFig. 1. Steps of MIPSE methods (Smart Polymer Nanocomposites. 2023: 121-139).

Common Polymer Precipitation Methods

One of the most common methods of polymer precipitation is the addition of a nonsolvent to the polymer solution under constant stirring. The nonsolvent gradually reduces the solubility of the polymer until it reaches a critical point, leading to its precipitation as solid particles. The size and morphology of the precipitated particles can be controlled by various factors such as the rate of nonsolvent addition, temperature, and the ratio of solvent to nonsolvent.

Polymer Reprecipitation Services

In Situ Polymer Precipitation

In situ polymer precipitation involves the direct production of polymer particles within a matrix material. This process involves dissolving a polymer precursor in a solvent, mixing it with a matrix material, and then adding a nonsolvent to cause precipitation. A polymer composite is created as a result of the dispersion of the resulting polymer particles throughout the matrix material.

Fractional Polymer Precipitation

Fractional precipitation polymer is a specialized form of polymer precipitation that is used to separate polymers of different molecular weights. This method involves the gradual addition of a nonsolvent to the polymer solution, leading to the precipitation of the highest molecular weight fraction first, followed by the lower molecular weight fractions. This technique is especially helpful for separating complicated polymer combinations, like those seen in biopolymers.

Our Polymer Precipitation Technologies

  • Salting-out method: by adding high-concentration brine, the polymer is combined with ions in the brine to form a complex and precipitate.
  • Solvent precipitation method: by adding non-solvent or hydrophilic solvent, the polymer cannot be dissolved in the solution and precipitated.
  • Cooling precipitation method: by cooling the polymer solution to a low temperature, the polymer loses its solubility and precipitates.
  • Aggregation and precipitation method: by adding an aggregation agent to the polymer solution, the polymer molecules interact and precipitate.
  • Aqueous phase precipitation method: by converting the polymer solution into the water phase, the polymer loses its solubility and precipitates.

Advantages of Our Polymer Precipitation Services

Polymer Reprecipitation Services

BOC Sciences has professional teams capable of preparing high-quality polymers and analytical support services according to customer requirements. We can choose the most suitable separation and purification method for different polymers to ensure that customers get the best quality polymers. In addition, we also offer comprehensive service support, including technical consultation, experimental design, data analysis, to ensure that customers get the best solution for polymer precipitation.

  • High-quality polymer preparation
  • Various polymer separation and purification methods
  • Fast service response time
  • Comprehensive service support

BOC Sciences is a specialized chemical and biotechnology service provider, providing high quality polymer precipitation services. Our polymer precipitation services include various services such as polymer preparation, polymer isolation and purification, aiming to provide customers with the best quality polymer precipitation solutions.

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