2,2'-BIPYRIDINE-3,3'-DIOL

Product Information

Molecular Formula:
C10H8N2O2
Molecular Weight:
188.18
Description
2,2'-Bipyridine-3,3'-diol is an important compound in the biomedical field, promoting a variety of inorganic and organometallic reactions. It is used as a reagent in drug synthesis to generate therapeutic compounds that relieve cardiovascular diseases such as angina and hypertension.
Synonyms
[2,2'-BIPYRIDYL]-3,3'-DIOL; 2,2'-BIPYRIDYL-3,3DIOL; 2,2'-BIPYRIDINE-3,3'-DIOL; 2,2'-BIS(3-PYRIDINOL); 2-(3-HYDROXY-2-PYRIDYL)-3-PYRIDINOL; 3,3'-DIHYDROXY-2,2'-BIPYRIDINE
IUPAC Name
2-(3-hydroxypyridin-2-yl)pyridin-3-ol
Canonical SMILES
Oc1cccnc1-c2ncccc2O
InChI
InChI=1S/C10H8N2O2/c13-7-3-1-5-11-9(7)10-8(14)4-2-6-12-10/h1-6,13-14H
InChI Key
RJNRKZBHLCOHNM-UHFFFAOYSA-N
Melting Point
194-196 ℃ (lit.)
Purity
98%
Density
1.363 g/cm3

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Signal Word
Warning

Computed Properties

XLogP3
0.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
1
Exact Mass
188.058577502 g/mol
Monoisotopic Mass
188.058577502 g/mol
Topological Polar Surface Area
66.2Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
169
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-112978709-A Carbon quantum dot precursor composition, carbon quantum dot and preparation method thereof 2019-12-12
US-2021061818-A1 Bipyridine and bipyrimidine gold(iii) dithiocarbamate complexes and methods of treating cancer 2019-08-28
WO-2020116037-A1 Polybutadiene, polybutadiene production method, polybutadiene composition, tire, and resin member 2018-12-05
US-2021171883-A1 Antiviral wiper 2018-08-29
TW-202003734-A Resin composition, laminate, semiconductor wafer with resin composition layer, mounting substrate for semiconductor with resin composition layer, and semiconductor device 2018-04-26
WO-2019208614-A1 Resin composition, laminate, resin composition layer-attached semiconductor wafer, substrate for mounting resin composition layer-attached semiconductor, and semiconductor device 2018-04-26
EP-3786200-A1 Resin composition, laminate, resin composition layer-attached semiconductor wafer, substrate for mounting resin composition layer-attached semiconductor, and semiconductor device 2018-04-26
KR-20210004971-A Resin composition, laminate, semiconductor wafer with resin composition layer, semiconductor mounting substrate with resin composition layer, and semiconductor device 2018-04-26
JP-WO2019208614-A1 Resin composition, laminate, semiconductor wafer with resin composition layer, semiconductor mounting substrate with resin composition layer, and semiconductor device 2018-04-26
US-2021277221-A1 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device 2018-04-26

Literatures

PMID Publication Date Title Journal
22913628 2012-09-20 Prototropism of [2,2'-bipyridyl]-3,3'-diol in albumin-SDS aggregates The journal of physical chemistry. B
22469101 2012-05-03 (2,2'-bipyridyl)-3-3'-diol in nafion: stabilization of unusual ground and excited states The journal of physical chemistry. B
21214252 2011-02-10 Modulation of ground- and excited-state dynamics of [2,2'-bipyridyl]-3,3'-diol by micelles The journal of physical chemistry. B
20957716 2010-12-03 Modulating the photochemistry of bipyridylic compounds by symmetric substitutions Chemphyschem : a European journal of chemical physics and physical chemistry
20419715 2010-06-11 Bipyridyl derivatives as photomemory devices: a comparative electronic-structure study Chemistry (Weinheim an der Bergstrasse, Germany)
19572684 2009-07-30 Excited-state diproton transfer in [2,2'-bipyridyl]-3,3'-diol: the mechanism is sequential, not concerted The journal of physical chemistry. A
18759240 2008-10-06 Study of the photochemical properties and conical intersections of [2,2'-bipyridyl]-3-amine-3'-ol Chemphyschem : a European journal of chemical physics and physical chemistry
18366045 2008-01-01 Luminescent excited-state intramolecular proton-transfer (ESIPT) dyes based on 4-alkyne-functionalized [2,2'-bipyridine]-3,3'-diol dyes Chemistry (Weinheim an der Bergstrasse, Germany)
17655352 2007-08-23 Investigating 2,2'-bipyridine-3,3'-diol as a microenvironment-sensitive probe: its binding to cyclodextrins and human serum albumin The journal of physical chemistry. B
17471481 2007-06-04 A comparative study on the photochemistry of two bipyridyl derivatives: [2,2'-bipyridyl]-3,3'-diamine and [2,2'-bipyridyl]-3,3'-diol Chemphyschem : a European journal of chemical physics and physical chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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