4,7,10-Trioxa-1,13-tridecanediamine

4,7,10-Trioxa-1,13-tridecanediamine is a polyethylene glycol (PEG)-based PROTAC linker. 4,7,10-Trioxa-1,13-tridecanediamine can be used in the synthesis of a series of PROTACs.

Bis[2-(3-aminopropoxy)ethyl] Ether; Diethylene glycol bis(3-aminopropyl) ether; DCA 221; 1,13-diamino-4,7,10-trioxatridecane; Bis-NH2-C1-PEG3

3-[2-[2-(3-aminopropoxy)ethoxy]ethoxy]propan-1-amine

C(CN)COCCOCCOCCCN

InChI=1S/C10H24N2O3/c11-3-1-5-13-7-9-15-10-8-14-6-2-4-12/h1-12H2

JCEZOHLWDIONSP-UHFFFAOYSA-N

310.6°C at 760 mmHg

-32°C

166 °C

95%

1.005 g/mL

clear colorless to light yellow liquid

Used to make polycondensation products, polyaddition products, copolymers, textile, leather, and paper auxiliaries, emulsifying agents, and corrosion inhibitors; Also used as a hardener and cross-linking agent for epoxy resins and in industrial adhesives.

4°C, protect from light; In solvent, -80°C, 6 months; -20°C, 1 month (protect from light)

n20/D 1.464 (lit.)

H314:
Causes severe skin burns and eye damage.

P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331:
IF SWALLOWED:
Rinse mouth.
Do NOT induce vomiting.
P303+P361+P353:
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. [As modified by IV ATP].
Rinse skin with water/shower.
P304+P340+P310:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338+P310:
IF IN EYES:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do. Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.