4-Cyanophenylboronic Acid

Reactant involved in: Oxidative hydroxylation; Trifluoromethylation; 1,4-Addition reactions. Precursor in the synthesis of inhibitors such as: Tpl2 kinase inhibitors; P2X7 antagonists used in the treatment of pain. Reagent used for: Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water; Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines with arylboronates; Ligand-free copper-catalyzed coupling of nitro arenes with arylboronic acids; Ferric perchlorate-promoted reaction of fullerenes with various arylboronic acids to give fullerenyl boronic esters; Phosphine-free Suzuki-Miyaura cross-coupling; Palladacycles as effective catalysts for multicomponent reaction with allylpalladium-intermediates; Chan-Lam-type Cu-catalyzed S-arylation of thiols ; Regioselective cross-coupling reactions under modfied Suzuki and Still cross-coupling reactions with Copper catalysis; Metal-free biaryl coupling in dimethyl carbonate as a solvent. Reagent used for Preparation of: Himbacine analogs as thrombin receptor antagonists and potential antiplatelet agents; Trisulfonated calixarene upper-rim sulfonamido and their complexation with trimethyllysine epigenetic mark; Antimalarial compounds via Suzuki cross-coupling; Deoxyuridine derivatives.

(4-cyanophenyl)boronic acid; (4-cyanophenyl)boronic acid

(4-cyanophenyl)boronic acid

B(C1=CC=C(C=C1)C#N)(O)O

InChI=1S/C7H6BNO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,10-11H

CEBAHYWORUOILU-UHFFFAOYSA-N

355.9 °C at 760 mmHg

>350 °C (lit.)

Not applicable

≥ 95 %

1.25 g/cm³

-0.76192

P261, P264, P270, P271, P280, P301+P310, P301+P312, P302+P352, P304+P340, P305+P351+P338, P311, P312, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P403+P233, P405, and P501

Danger