Benzyl glycidyl ether

Inquiry

Molecular Formula:

C10H12O2

Molecular Weight:

164.20

CAS Number:

2930-05-4

Catalog Number:

2930-05-4

Product Information

Molecular Formula:

C10H12O2

Molecular Weight:

164.20

Description

Benzyl glycidyl ether is a remarkable biomedical compound harnessed in the advancement of pharmaceutical drugs and assumes paramount significance. Its extraordinary attributes render it an invaluable constituent in the synthesis of antitumor agents and cardiovascular medication, revolutionizing the treatment landscape for numerous ailments spanning cancer and heart-related conditions. The intricate modus operandi of this compound unequivocally showcases its potential as an efficacious therapeutic entity within the biomedical realm.

Synonyms

Oxirane, 2-[(phenylmethoxy)methyl]-; 2-[(Phenylmethoxy)methyl]oxirane; Oxirane, [(phenylmethoxy)methyl]-; Propane, 1-(benzyloxy)-2,3-epoxy-; (Benzyloxymethyl)oxirane; (±)-O-Benzylglycidol; 1-(Benzyloxy)-2,3-epoxypropane; 2-(Benzyloxymethyl)oxirane; 2-[[(Benzyloxy)methyl]oxy]oxirane; 3-(Benzyloxy)-1,2-epoxypropane; [(Phenylmethoxy)methyl]oxirane; Diluent 692; Glycidol benzyl ether; Glycidyl benzyl ether; JX 011; LS 692; NXA 692; Xinyuan 692; XY 692; YS 692

IUPAC Name

2-(phenylmethoxymethyl)oxirane

Canonical SMILES

C1C(O1)COCC2=CC=CC=C2

InChI

InChI=1S/C10H12O2/c1-2-4-9(5-3-1)6-11-7-10-8-12-10/h1-5,10H,6-8H2

InChI Key

QNYBOILAKBSWFG-UHFFFAOYSA-N

Boiling Point

78-80°C

Melting Point

89.5-90.1°C

Purity

≥95%

Density

1.0960 g/cm³

Appearance

Colorless to Light Yellow Clear Liquid

Storage

Store at 2-8°C

Refractive Index

1.52

LogP

1.60200

Safety Information

Hazards

H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H341:
Suspected of causing genetic defects.

Precautionary Statement

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501

Signal Word

Warning

Computed Properties

XLogP3

1.3

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

164.083729621 g/mol

Monoisotopic Mass

164.083729621 g/mol

Topological Polar Surface Area

21.8Å²

Heavy Atom Count

Formal Charge

Complexity

130

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
CN-114163934-A	Method for improving binding force between steel plate and mortar	2021-12-23
CN-114181651-A	Elastic easily-detachable epoxy floor glue and preparation method thereof	2021-12-20
CN-113980425-A	Foam filler and preparation method thereof	2021-11-30
CN-114133841-A	Super-black coating, LED display screen and preparation method of LED display screen	2021-11-30
CN-114133825-A	Solvent-free epoxy resin coating and preparation method and application thereof	2021-11-25
CN-114163614-A	Epoxy curing agent and preparation method and application thereof	2021-11-22
CN-114031896-A	Epoxy resin composition for carbon fiber winding and preparation method thereof	2021-11-20
CN-113860797-A	High-strength lightweight aggregate for concrete and preparation method thereof	2021-11-19
CN-113930052-A	Pultrusion method of high-viscosity epoxy resin composition for carbon fiber	2021-11-18
CN-113980623-A	Bio-based high-strength joint filling repair heat insulation material and preparation method thereof	2021-11-18

Literatures

PMID	Publication Date	Title	Journal
22052437	2012-08-01	Bioresolution of benzyl glycidyl ether using whole cells of Bacillus alcalophilus	Journal of basic microbiology
22526421	2012-08-01	Biocatalytic resolution of benzyl glycidyl ether and its derivates by Talaromyces flavus: effect of phenyl ring substituents on enantioselectivity	Biotechnology letters
20549284	2011-04-01	Marine fungi Aspergillus sydowii and Trichoderma sp. catalyze the hydrolysis of benzyl glycidyl ether	Marine biotechnology (New York, N.Y.)
17875334	2007-10-15	Cloning of an epoxide hydrolase-encoding gene from Aspergillus niger M200, overexpression in E. coli, and modification of activity and enantioselectivity of the enzyme by protein engineering	Journal of biotechnology
16343776	2006-02-01	Purification and characterisation of a novel enantioselective epoxide hydrolase from Aspergillus niger M200	Biochimica et biophysica acta
16061300	2005-12-06	Novel microbial epoxide hydrolases for biohydrolysis of glycidyl derivatives	Journal of biotechnology
15471449	2004-10-15	Synthesis of 4-deoxy-L-(and D-)hexoses from chiral noncarbohydrate building blocks	The Journal of organic chemistry
14552765	2003-11-03	Practical, asymmetric synthesis of 16-hydroxyeicosa-5(Z),8(Z), 11(Z),14(Z)-tetraenoic acid (16-HETE), an endogenous inhibitor of neutrophil activity	Bioorganic & medicinal chemistry letters
11412980	2001-06-18	Discovery and characterization of the potent, selective and orally bioavailable MMP inhibitor ABT-770	Bioorganic & medicinal chemistry letters

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