Cyclopentyl methyl ether

Inquiry

Molecular Formula:

C6H12O

Molecular Weight:

100.16

CAS Number:

5614-37-9

Catalog Number:

5614-37-9

Product Information

Molecular Formula:

C6H12O

Molecular Weight:

100.16

Description

• Cyclopentyl methyl ether (CPME) is an alternative to ether solvents such as THF, diethyl ether, and MTBE with a higher resistance to peroxide formation.• The more environmentally conservative CPME solvent replaces hazardous solvents in order to achieve sustainability and reduce environmental and operational costs.• CPME offers considerable potential and advantage as a direct replacement for CH2Cl2 in binary eluents using MeOH as the modifier with MeOH-DMC and i-PrOH-EtOAc.
Green Alternative to THF, tert-Butyl methyl ether (MTBE), 1,4 Dioxane and other ether solventsThe toxicological assessment of cyclopentyl methyl ether (CPME) as a green solvent.

Synonyms

CYCLOPENTYL METHYL ETHER; METHOXYCYCLOPENTANE; Cyclopentyl methyl ether, ReagentPlus(R), >=99.90%; Cyclopentyl methyl ether, anhydrous, >=99.9%; CYCLOPENTYL METHYL ETHER, WITH STABILIZER; Cyclopentyl methyl ether, 99.9+%

IUPAC Name

methoxycyclopentane

Canonical SMILES

COC1CCCC1

InChI

InChI=1S/C6H12O/c1-7-6-4-2-3-5-6/h6H,2-5H2,1H3

InChI Key

SKTCDJAMAYNROS-UHFFFAOYSA-N

Boiling Point

106°C

Melting Point

-140°C

Flash Point

30.2 °F - closed cup

Purity

95%

Density

0.86

Storage

Flammables area

Safety Information

Hazards

H225 - H302 - H315 - H319 - H412

Precautionary Statement

P210 - P301 + P312 + P330 - P305 + P351 + P338 - P370 + P378 - P403 + P235

Computed Properties

XLogP3

1.3

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

100.088815002 g/mol

Monoisotopic Mass

100.088815002 g/mol

Topological Polar Surface Area

9.2Å²

Heavy Atom Count

Formal Charge

Complexity

46.1

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
CN-114181189-A	Method for purifying cyclic lactide	2021-12-16
JP-2022037094-A	Method for producing a polyene compound having a hydroxyl group	2021-12-14
CN-114106043-A	Compound, preparation method thereof, method for preparing citicoline by compound and application	2021-12-06
CN-114105882-A	Imidazole structure group-based isocyanate electrolyte additive and application thereof	2021-11-24
CN-113980250-A	Conjugated polymer material capable of being processed by green solvent and preparation method thereof	2021-11-20
CN-113845692-A	Polycarbosilane/phenolic aldehyde dual-system network structure aerogel and composite material and preparation method thereof	2021-11-19
CN-113979855-A	Preparation method of crotonic acid	2021-11-17
CN-113801033-A	Synthesis method of 2-aminoindan or derivatives thereof	2021-11-16
CN-113801033-B	Synthesis method of 2-aminoindan or derivatives thereof	2021-11-16
CN-114105822-A	Pseudo C2Symmetrical chiral diallyl substituted compound and preparation method and application thereof	2021-11-16

Literatures

PMID	Publication Date	Title	Journal
22699568	2012-06-14	Ring-expansion reaction of oximes with aluminum reductants	Molecules (Basel, Switzerland)
21337529	2011-04-18	Cyclopentyl methyl ether: an alternative solvent for palladium-catalyzed direct arylation of heteroaromatics	ChemSusChem
19323570	2009-04-03	Recycling the tert-butanesulfinyl group in the synthesis of amines using tert-butanesulfinamide	The Journal of organic chemistry
18493644	2008-06-01	2-Methoxycyclopentyl analogues of a Pseudomonas aeruginosa quorum sensing modulator	Molecular bioSystems
17877405	2007-10-12	Practical and robust method for regio- and stereoselective preparation of (E)-ketene tert-butyl TMS acetals and beta-ketoester-derived tert-butyl (1Z,3E)-1,3-bis(TMS)dienol ethers	The Journal of organic chemistry
15810842	2005-04-13	Highly enantioselective phase-transfer-catalyzed alkylation of protected alpha-amino acid amides toward practical asymmetric synthesis of vicinal diamines, alpha-amino ketones, and alpha-amino alcohols	Journal of the American Chemical Society
15834802	2005-03-01	Enhancement of enzyme activity and enantioselectivity by cyclopentyl methyl ether in the transesterification catalyzed by Pseudomonas cepacia lipase co-lyophilized with cyclodextrins	Biotechnology letters

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