L(-)-Camphor

Inquiry

Molecular Formula:

C10H16O

Molecular Weight:

152.23

CAS Number:

464-48-2

Catalog Number:

464-48-2

Product Information

Molecular Formula:

C10H16O

Molecular Weight:

152.23

Description

L-camphor appears as colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68 °F: 40. Flash point 149 °F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure; 14% sublimes within 60 minutes at 176 °F and 12 mmHg.

Synonyms

(-)-Alcanfor; (1s,4s)-(-)-campho; 7,7-trimethyl-(1s)-bicyclo(2.2.1)heptan-2-on; 7,7-trimethyl-(1s)-bicyclo[2.2.1]heptan-2-on; Camphor, (1S,4S)-(-)-; Camphor, l-, (-)-; CAMPHORE; Levo-(-)-camphor

IUPAC Name

(1S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

Canonical SMILES

CC1(C2CCC1(C(=O)C2)C)C

InChI

InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m0/s1

InChI Key

DSSYKIVIOFKYAU-OIBJUYFYSA-N

Boiling Point

204ºC

Melting Point

178-180ºC

Flash Point

150 °F

Purity

>96.0%(GC)

Density

0.990

Solubility

1 g/800 mL at 77 °F

Appearance

Colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68°F: 40. Flash point 149°F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure; 14% sublimes within 60

Application

Naturally occurring form of camphor; Used in organic synthesis and as an odorant, flavoring agent, moth repellent, preservative, and plasticizer in cosmetics; Also used as a topical analgesic and antipruritic; Used as a plasticizer for cellulose esters and ethers, to make plastics, cymene, and incense, in lacquers, varnishes, explosives, embalming fluids, pyrotechnics, and insect repellents.

Vapor Pressure

1 mmHg at 106.7 °F

Safety Information

Hazards

H228:
Flammable solid.
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.

Precautionary Statement

P210:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P370+P378:
In case of fire:
Use for extinction:
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.

Computed Properties

XLogP3

2.2

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

152.120115130 g/mol

Monoisotopic Mass

152.120115130 g/mol

Topological Polar Surface Area

17.1Å²

Heavy Atom Count

Formal Charge

Complexity

217

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
CN-113693962-A	Fibronectin-containing multiple protein repair composition and preparation method thereof	2021-08-09
CN-112716829-A	Brightening and whitening composition	2021-02-23
JP-2021075562-A	Cosmetics	2021-02-10
CN-112741773-A	Active matter wrapping method	2021-02-07
CN-112754978-A	Moisturizing, relieving and repairing composition	2021-02-03
CN-112932996-A	Whitening composition and essence thereof	2021-02-03
CN-112662639-A	Short-chain alcohol dehydrogenase and application thereof	2021-01-21
WO-2022029579-A1	Emulsifier composition for personal care formulation	2020-08-05
JP-2022021339-A	A resin composition for forming an odor substance receiving layer, a sensor element using the resin composition, an odor sensor, and an odor measuring device.	2020-07-21
JP-2022021340-A	A resin composition for forming an odor substance receiving layer, a sensor element using the resin composition, an odor sensor, and an odor measuring device.	2020-07-21

Literatures

PMID	Publication Date	Title	Journal
23828908	2013-09-01	Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin	Chemical senses
23625413	2013-05-01	Camphor modulates TRPV3 cation channels activity by interacting with critical pore-region cysteine residues	Pakistan journal of pharmaceutical sciences
17268056	2007-02-01	In vitro metabolism of (-)-camphor using human liver microsomes and CYP2A6	Biological & pharmaceutical bulletin
16939314	2006-09-06	Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils	Journal of agricultural and food chemistry
16192383	2005-09-28	Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism	The Journal of neuroscience : the official journal of the Society for Neuroscience

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