Methyl gallate

Product Information

Molecular Formula:
C8H8O5
Molecular Weight:
184.15
Description
Methyl gallate isolated from the herbs of Sapium sebiferum. It is a reverse transcriptase inhibitor.
Synonyms
Methyl 3,4,5-trihydroxybenzoate; 3,4,5-trihydroxy-benzoicacimethylester
IUPAC Name
methyl 3,4,5-trihydroxybenzoate
Canonical SMILES
COC(=O)C1=CC(=C(C(=C1)O)O)O
InChI
InChI=1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3
InChI Key
FBSFWRHWHYMIOG-UHFFFAOYSA-N
Boiling Point
450.1±40.0 °C at 760 mmHg
Melting Point
201-203 °C (lit.)
Flash Point
190.8±20.8 °C
Purity
0.98
Density
1.5±0.1 g/cm3
Solubility
In vitro:
10 mM in DMSO
Appearance
Powder
Application
Used as an antioxidant.
Storage
Powder:
-20°C: 3 years
4°C: 2 years
In solvent:
-80°C: 6 months
-20°C: 1 month
Vapor Pressure
0.0±1.1 mmHg at 25°C

Safety Information

Hazards
H302 - H315 - H319 - H335
Precautionary Statement
P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338

Computed Properties

XLogP3
0.9
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
2
Exact Mass
184.03717335 g/mol
Monoisotopic Mass
184.03717335 g/mol
Topological Polar Surface Area
87Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
181
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114099522-A 1,2,3,4, 6-O-pentagalloyl glucose used as serine protease inhibitor, screening method and application 2021-11-24
CN-113980858-A Lactobacillus plantarum YL399 for producing high-activity tannase and application thereof in preparation of codonopsis pilosula fermented feed 2021-11-18
CN-113999144-A Amphiphilic molecular compound, preparation method and amphiphilic nano material 2021-11-18
CN-114085241-A Probe for detecting and identifying tea polyphenol and preparation method and application thereof 2021-11-18
CN-113980485-A Biological enzyme compound and method for applying biological enzyme compound to plant extraction process 2021-11-16
CN-113862000-A Liquid crystal polymer with continuously adjustable fluorescence color and preparation method thereof 2021-11-09
CN-113973999-A Fermented compound traditional Chinese medicine additive for improving sow amniotic fluid volume and PSY and preparation method thereof 2021-10-27
CN-114099488-A Application of gallic acid or its derivative in inducing differentiation and proliferation of neural stem cell 2021-10-13
CN-113917031-A Method for determining blood concentration of lung-tonifying and blood-activating capsule in vivo by UHPLC-MS/MS method 2021-10-12
CN-113728776-A Balanced fertilization method for landscaping goldenrain tree 2021-09-28

Literatures

PMID Publication Date Title Journal
32112863 2020-04-01 Methyl gallate: Selective antileishmanial activity correlates with host-cell directed effects Chemico-biological interactions
27777014 2016-12-25 Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells Chemico-biological interactions
23684720 2013-07-09 Antimicrobial activity of Schinus lentiscifolius (Anacardiaceae) Journal of ethnopharmacology
22891951 2012-09-12 Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori Journal of agricultural and food chemistry
22144737 2012-09-01 Antimetastatic potentials of Phyllanthus urinaria L on A549 and Lewis lung carcinoma cells via repression of matrix-degrading proteases Integrative cancer therapies
22277734 2012-05-01 Isolation and characterization of ellagitannins as the major polyphenolic components of Longan (Dimocarpus longan Lour) seeds Phytochemistry
22490328 2012-04-10 A gallotannin-rich fraction from Caesalpinia spinosa (Molina) Kuntze displays cytotoxic activity and raises sensitivity to doxorubicin in a leukemia cell line BMC complementary and alternative medicine
22538659 2012-04-01 Antiviral activities of flavonoids isolated from the bark of Rhus verniciflua stokes against fish pathogenic viruses In Vitro Journal of microbiology (Seoul, Korea)
22447026 2012-03-23 Screening of anti-obesity agent from herbal mixtures Molecules (Basel, Switzerland)
22082098 2012-03-01 Anti-inflammatory activity of Pistacia khinjuk in different experimental models: isolation and characterization of its flavonoids and galloylated sugars Journal of medicinal food
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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