OctMAB

Product Information

Molecular Formula:
C21H46BrN
Molecular Weight:
392.5
Description
OctMAB is a dynamin inhibitor with IC50 value of 1.9 μM for dynamin I. It can also inhibit receptor-mediated endocytosis.
Synonyms
Octadecyltrimethylammonium bromide
IUPAC Name
trimethyl(octadecyl)azaniumbromide
Canonical SMILES
CCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
InChI
InChI=1S/C21H46N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(2,3)4;/h5-21H2,1-4H3;1H/q+1;/p-1
InChI Key
SZEMGTQCPRNXEG-UHFFFAOYSA-M
Melting Point
250°C (dec.)
Purity
≥95%
Appearance
White to Almost white powder to crystal
Stability
Stable. Hygroscopic. Incompatible with strong oxidizing agents. Protect from moisture.

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
17
Exact Mass
391.28136 g/mol
Monoisotopic Mass
391.28136 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
23
Formal Charge
0
Complexity
204
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114107966-A Chemical composite plating method for tractor axle differential shell 2022-01-25
CN-114032682-A Dyeing and finishing process of polyester-linen blended fabric 2021-12-25
CN-114149062-A Bactericide for sulfate reducing bacteria in polymer-containing produced liquid and preparation method and application thereof 2021-12-17
CN-113930230-A Thick oil viscosity reducer and preparation method thereof 2021-12-16
CN-114180545-A Copper removal method and method for preparing iron phosphate from waste lithium iron phosphate battery core powder 2021-12-10
CN-114163862-A Multilevel structure carbon material, preparation method thereof and anticorrosive paint 2021-12-07
CN-114086223-A Preparation method of acid bath, copper deposit and plating homogenizing agent 2021-12-06
CN-114058133-A Preparation method of high-creep-resistance PS material 2021-12-02
CN-114133295-A Preparation method of magnesium intercalated montmorillonite modified biochar composite material 2021-11-30
CN-114181693-A Cationic surfactant/DCFH-DA nano reaction system and preparation method thereof 2021-11-26

Literatures

PMID Publication Date Title Journal
20863617 2010-12-15 Uranium sorption on bentonite modified by octadecyltrimethylammonium bromide Journal of hazardous materials
20571068 2010-07-01 The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells Molecular cancer therapeutics
19836132 2010-01-15 Effect of groups difference in surfactant on solubilization of aqueous phenol using MEUF Journal of hazardous materials
19366220 2009-04-21 Electrochemical and spectroscopic study of octadecyltrimethylammonium bromide/DNA surfoplexes Langmuir : the ACS journal of surfaces and colloids
18642844 2008-08-27 Effect of different wood pretreatments on the sorption-desorption of linuron and metalaxyl by woods Journal of agricultural and food chemistry
17532126 2008-01-15 Influence of clay mineral structure and surfactant nature on the adsorption capacity of surfactants by clays Journal of hazardous materials
17702890 2007-12-01 Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II Molecular pharmacology
17416387 2007-08-15 Microstructure and structural transition in coconut oil microemulsion using semidifferential electroanalysis Journal of colloid and interface science
17418856 2007-07-15 Thermal stability of octadecyltrimethylammonium bromide modified montmorillonite organoclay Journal of colloid and interface science
17320152 2007-05-25 Retention of pesticides in soil columns modified in situ and ex situ with a cationic surfactant The Science of the total environment
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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