Orlistat USP Related Compound C (Triphenylphosphine Oxide)

Product Information

Molecular Formula:
C18H15OP
Molecular Weight:
278.29
Description
An impurity of Orlistat, which a pancreatic lipase inhibitor acting locally in the gastrointestinal tract to inhibit lipase.
Synonyms
Triphenylphosphine Oxide; Triphenylphosphine Monoxide; Orlistat Related Compound C; Orlistat USP Related Compound C;
IUPAC Name
diphenylphosphorylbenzene
Canonical SMILES
C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChI=1S/C18H15OP/c19-20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
InChI Key
FIQMHBFVRAXMOP-UHFFFAOYSA-N
Boiling Point
360 °C
Melting Point
152-160 °C
Flash Point
356.0 °F - closed cup
Purity
≥ 99.5% (Assay)
Density
1,212 g/cm3
Solubility
Soluble in Chloroform, Ethyl Acetate, Methanol
Appearance
White crystal powder
Application
Used for processing (extraction, separation, and spectrophotometric determination) environmental samples of cadmium and mercury.
Storage
Store at RT

Safety Information

Hazards
H302 - H315 - H319 - H335
Precautionary Statement
P261 - P305 + P351 + P338

Computed Properties

XLogP3
2.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
3
Exact Mass
278.086052095 g/mol
Monoisotopic Mass
278.086052095 g/mol
Topological Polar Surface Area
17.1Ų
Heavy Atom Count
20
Formal Charge
0
Complexity
281
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113999372-A Phosphorus-containing super-crosslinked porous organic polymer material and preparation method and application thereof 2021-12-21
JP-2022040133-A A photosensitive coloring composition for a color filter for a solid-state image sensor, a color filter, and a solid-state image sensor using the same. 2021-12-15
CN-114163621-A Preparation method and application of epoxidized soybean oil and glycolide copolymerization bio-based elastomer 2021-12-08
CN-113880724-A Preparation method of 3- (2-aminophenyl) -2-acrylate 2021-12-06
CN-114130791-A Harmless treatment system for solid waste triphenylphosphine oxide in electronic industry 2021-12-02
CN-114057558-A Synthetic method, catalytic system and application of 3,5, 5-trimethylhexanal 2021-12-01
CN-113860317-A Method for producing silicon dioxide by synthesis method 2021-11-24
CN-114100541-A Method for synthesizing isononanal by microchannel reaction device 2021-11-23
CN-114014859-A Triazole indolol compound and synthesis method thereof 2021-11-22
CN-114031918-A Polycarbonate composition with low yellowness index, and preparation method and application thereof 2021-11-22

Literatures

PMID Publication Date Title Journal
27725436 2016-01-01 Ligand Activity of Group 15 Compounds Possessing Triphenyl Substituent for the RXR and PPARγ Nuclear Receptors Biological & pharmaceutical bulletin
25787141 2015-06-01 Deoxynivalenol (Vomitoxin)-Induced Cholecystokinin and Glucagon-Like Peptide-1 Release in the STC-1 Enteroendocrine Cell Model Is Mediated by Calcium-Sensing Receptor and Transient Receptor Potential Ankyrin-1 Channel Toxicological sciences : an official journal of the Society of Toxicology
23022238 2012-11-02 Gas chromatographic determination of phosphate-based flame retardants in styrene-based polymers from waste electrical and electronic equipment Journal of chromatography. A
22757962 2012-07-16 Varying the Lewis base coordination of the Y2N2 core in the reduced dinitrogen complexes {[(Me3Si)2N]2(L)Y}2(μ-η2:η2-N2) (L = benzonitrile, pyridines, triphenylphosphine oxide, and trimethylamine N-oxide) Inorganic chemistry
22670799 2012-06-20 A direct route to bis(imido)uranium(V) halides via metathesis of uranium tetrachloride Journal of the American Chemical Society
21847610 2012-06-01 A convenient route to optically pure α-alkyl-β-(sec-amino)alanines Amino acids
22146808 2012-04-21 Establishing the mechanism of Rh-catalysed activation of O2 by H2 Dalton transactions (Cambridge, England : 2003)
22589958 2012-04-01 7-Benzyl-3-(4-fluoro-phen-yl)-2-propyl-amino-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one Acta crystallographica. Section E, Structure reports online
22412686 2012-03-01 7-Benzyl-3-(4-chloro-phen-yl)-2-isobutyl-amino-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one Acta crystallographica. Section E, Structure reports online
22094964 2012-02-27 The influence of reversible trianionic pincer OCO(3-)μ-oxo Cr(IV) dimer formation ([Cr(IV)]2(μ-O)) and donor ligands in oxygen-atom-transfer (OAT) Dalton transactions (Cambridge, England : 2003)
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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