3,6-Dimethyl-1,4-dioxane-2,5-dione

Catalog Number Size Price Stock Quantity
B1370-333424 100 g $299 In stock
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Product Information

Molecular Formula:
C6H8O4
Molecular Weight:
144.13
Description
3,6-Dimethyl-1,4-dioxane-2,5-dione can be used in the synthesis of biodegradable homo- and copolymers.
Synonyms
Lactide; DL-Lactide; 3,6-Diketo-2,5-dimethyl-1,4-dioxane; 3,6-Dimethyl-p-dioxane-2,5-dione
IUPAC Name
3,6-dimethyl-1,4-dioxane-2,5-dione
Canonical SMILES
CC1C(=O)OC(C(=O)O1)C
InChI
InChI=1S/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3
InChI Key
JJTUDXZGHPGLLC-UHFFFAOYSA-N
Boiling Point
138 °C at 8 torr
Melting Point
116-119 °C
Flash Point
180°C
Purity
95 %
Density
1.186 g/cm3
Solubility
water: 3165 mg/L at 25 °C (est)
Appearance
White crystalline powder
Application
Used to make polylactic acid and cosmetics.
Storage
Refrigerator (+4 °C)
LogP
-0.13660

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264, P280, P305+P351+P338, and P337+P313
Signal Word
Warning

Computed Properties

XLogP3
0.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
144.04225873 g/mol
Monoisotopic Mass
144.04225873 g/mol
Topological Polar Surface Area
52.6Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
155
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
US-2021188799-A1 Synthesis method and device for rapidly producing lactide at high yield 2021-03-04
US-10959969-B1 Methods of treating SARS Cov-2 virus with protocatechuic acid 2020-07-24
US-2021186491-A1 Suture packages having integrated suture straightening assemblies 2019-12-24
EP-3839043-A1 Screening methods for compounds modulating polyamine transport 2019-12-20
WO-2021121412-A1 Leadless pacemaker and tail end component and head end component thereof 2019-12-20
WO-2021123655-A1 Method for manufacturing a polyester containing at least one 1,4:3,6-dianhydrohexitol unit with reduced colouring and improved rates of incorporation of the unit(s) 2019-12-20
WO-2021124301-A1 Formulations and method for treatment of inflammatory diseases 2019-12-20
WO-2021125236-A1 Biaxially oriented polyester film and method for producing same 2019-12-20
EP-3838976-A1 Process for degrading plastic products 2019-12-19
WO-2021119727-A1 Biocompatible material 2019-12-19

Literatures

PMID Publication Date Title Journal
22088756 2012-11-01 Poly (N-isopropylacrylamide)-PLA and PLA blend nanoparticles for temperature-controllable drug release and intracellular uptake Colloids and surfaces. B, Biointerfaces
22961054 2012-10-28 Alkaline earth metal complexes of a chiral polyether as initiator for the ring-opening polymerization of lactide Dalton transactions (Cambridge, England : 2003)
22968601 2012-10-25 Nacnac(Bn)CuOiPr: a strained geometry resulting in very high lactide polymerization activity Chemical communications (Cambridge, England)
23016983 2012-10-24 Tandem metal-coordination copolymerization and organocatalytic ring-opening polymerization via water to synthesize diblock copolymers of styrene oxide/CO2 and lactide Journal of the American Chemical Society
23009063 2012-10-15 Stereoselective synthesis of biphenolate/binaphtolate titanate and zirconate alkoxide species: structural characterization and use in the controlled ROP of lactide Inorganic chemistry
23030249 2012-10-15 Synthesis and characterization of amine-bridged bis(phenolate)lanthanide alkoxides and their application in the controlled polymerization of rac-lactide and rac-β-butyrolactone Inorganic chemistry
22903466 2012-10-14 Dimethylaluminium aldiminophenolates: synthesis, characterization and ring-opening polymerization behavior towards lactides Dalton transactions (Cambridge, England : 2003)
22561339 2012-10-10 Dual-purpose magnetic micelles for MRI and gene delivery Journal of controlled release : official journal of the Controlled Release Society
22930321 2012-10-09 Highly heteroselective ring-opening polymerization of racemic lactide initiated by divalent ytterbium complexes bearing amino bis(phenolate) ligands Chemical communications (Cambridge, England)
22892614 2012-10-07 Al and Zn complexes bearing N,N,N-tridentate quinolinyl anilido-imine ligands: synthesis, characterization and catalysis in L-lactide polymerization Dalton transactions (Cambridge, England : 2003)
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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