1,3-Dioxan-2-one
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-185003 | 10 g | $199 | In stock | |
| BPM-185003 | 25 g | $419 | In stock |
Product Information
Molecular Formula
C4H6O3
Molecular Weight
102.09
Description
1,3-Dioxan-2-one is a commonly used pharmaceutical intermediate in the biomedical industry. It plays a pivotal role in synthesizing numerous drugs like Heterocyclic Compounds and antibiotics where it facilitates and speeds up the chemical reaction process.
Synonyms
Trimethylene Carbonate
IUPAC Name
1,3-dioxan-2-one
SMILES
C1COC(=O)OC1
InChI
InChI=1S/C4H6O3/c5-4-6-2-1-3-7-4/h1-3H2
InChI Key
YFHICDDUDORKJB-UHFFFAOYSA-N
Boiling Point
255.2±9.0 °C at 760 mmHg
Melting Point
45.0 to 49.0 °C
Purity
98%
Density
1.2±0.1 g/cm3
Appearance
White Low-melting Crystals
Safety Information
Hazards
H319:
Causes serious eye irritation.
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:
IF IN EYES:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do. Continue rinsing.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:
IF IN EYES:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do. Continue rinsing.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
Signal Word
Warning
QC Data
Computed Properties
XLogP3
0.7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
0
Exact Mass
102.031694049 g/mol
Monoisotopic Mass
102.031694049 g/mol
Topological Polar Surface Area
35.5Ų
Heavy Atom Count
7
Formal Charge
0
Complexity
71
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114133508-A | High-performance lignin-based polyurethane and preparation method thereof | 2022-01-14 |
| CN-114181360-A | Ultrasonic wave stimulus response polyurethane and preparation method thereof | 2021-12-08 |
| CN-114044888-A | Hydrolytically degradable polymers, method for the production thereof and use thereof | 2021-12-07 |
| CN-114099787-A | Absorbable biological membrane, preparation method and application thereof | 2021-11-29 |
| CN-114099794-A | Bioabsorbable orthopedic implant material and preparation method thereof | 2021-11-18 |
| CN-114122512-A | Solid electrolyte, method for preparing the same, and solid secondary battery comprising the same | 2021-11-11 |
| CN-114044875-A | Thermoplastic polyurethane elastomer and preparation method and application thereof | 2021-11-04 |
| CN-114099464-A | Targeting nanoparticles for treating leukemia and preparation method and application thereof | 2021-11-04 |
| CN-114088254-A | High-linearity flexible pressure sensor with adjustable sensitivity and preparation method thereof | 2021-10-22 |
| CN-114159980-A | Preparation method of pH-responsive anti-pollution composite nanofiltration membrane | 2021-10-22 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22416030 | 2012-05-01 | Photo-crosslinked biodegradable hydrogels prepared from fumaric acid monoethyl ester-functionalized oligomers for protein delivery | Macromolecular bioscience |
| 22301176 | 2012-02-01 | Triblock copolymers of ε-caprolactone, trimethylene carbonate, and L-lactide: effects of using random copolymer as hard-block | Journal of the mechanical behavior of biomedical materials |
| 22346983 | 2012-02-01 | (4Z,6Z)-4,6-Bis(4-meth-oxy-benzyl-idene)-2,2-dimethyl-1,3-dioxan-5-one | Acta crystallographica. Section E, Structure reports online |
| 22906331 | 2012-01-01 | Preliminary study of hiatal hernia repair using polyglycolic acid: trimethylene carbonate mesh | JSLS : Journal of the Society of Laparoendoscopic Surgeons |
| 21300552 | 2011-12-01 | Evaluation of post-surgical relapse in maxillary surgery using resorbable plate | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery |
| 21518006 | 2011-11-01 | Biodegradation, soft and hard tissue integration of various polyethylene glycol hydrogels: a histomorphometric study in rabbits | Clinical oral implants research |
| 21979188 | 2011-11-01 | Evaluation of a new synthetic plug in the treatment of anal fistulas: results of a pilot study | Diseases of the colon and rectum |
| 21793195 | 2011-10-01 | Triblock copolymers of ε-caprolactone, L-lactide, and trimethylene carbonate: biodegradability and elastomeric behavior | Journal of biomedical materials research. Part A |
| 21388891 | 2011-09-01 | Reduction in anastomotic strictures using bioabsorbable circular staple line reinforcement in laparoscopic gastric bypass | Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery |
| 21664305 | 2011-09-01 | Oligo(trimethylene carbonate)-poly(ethylene glycol)-oligo(trimethylene carbonate) triblock-based hydrogels for cartilage tissue engineering | Acta biomaterialia |
