3,6-Dimethyl-1,4-dioxane-2,5-dione
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-333424 | 100 g | $299 | In stock |
Product Information
Molecular Formula
C6H8O4
Molecular Weight
144.13
Description
3,6-Dimethyl-1,4-dioxane-2,5-dione can be used in the synthesis of biodegradable homo- and copolymers.
Synonyms
Lactide; DL-Lactide; 3,6-Diketo-2,5-dimethyl-1,4-dioxane; 3,6-Dimethyl-p-dioxane-2,5-dione
IUPAC Name
3,6-dimethyl-1,4-dioxane-2,5-dione
SMILES
CC1C(=O)OC(C(=O)O1)C
InChI
InChI=1S/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3
InChI Key
JJTUDXZGHPGLLC-UHFFFAOYSA-N
Boiling Point
138 °C at 8 torr
Melting Point
116-119 °C
Flash Point
180°C
Purity
95 %
Density
1.186 g/cm3
Solubility
water: 3165 mg/L at 25 °C (est)
Appearance
White crystalline powder
Application
Used to make polylactic acid and cosmetics.
Storage
Refrigerator (+4 °C)
LogP
-0.13660
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264, P280, P305+P351+P338, and P337+P313
Signal Word
Warning
QC Data
Computed Properties
XLogP3
0.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
144.04225873 g/mol
Monoisotopic Mass
144.04225873 g/mol
Topological Polar Surface Area
52.6Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
155
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2021188799-A1 | Synthesis method and device for rapidly producing lactide at high yield | 2021-03-04 |
| US-10959969-B1 | Methods of treating SARS Cov-2 virus with protocatechuic acid | 2020-07-24 |
| US-2021186491-A1 | Suture packages having integrated suture straightening assemblies | 2019-12-24 |
| EP-3839043-A1 | Screening methods for compounds modulating polyamine transport | 2019-12-20 |
| WO-2021121412-A1 | Leadless pacemaker and tail end component and head end component thereof | 2019-12-20 |
| WO-2021123655-A1 | Method for manufacturing a polyester containing at least one 1,4:3,6-dianhydrohexitol unit with reduced colouring and improved rates of incorporation of the unit(s) | 2019-12-20 |
| WO-2021124301-A1 | Formulations and method for treatment of inflammatory diseases | 2019-12-20 |
| WO-2021125236-A1 | Biaxially oriented polyester film and method for producing same | 2019-12-20 |
| EP-3838976-A1 | Process for degrading plastic products | 2019-12-19 |
| WO-2021119727-A1 | Biocompatible material | 2019-12-19 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22088756 | 2012-11-01 | Poly (N-isopropylacrylamide)-PLA and PLA blend nanoparticles for temperature-controllable drug release and intracellular uptake | Colloids and surfaces. B, Biointerfaces |
| 22961054 | 2012-10-28 | Alkaline earth metal complexes of a chiral polyether as initiator for the ring-opening polymerization of lactide | Dalton transactions (Cambridge, England : 2003) |
| 22968601 | 2012-10-25 | Nacnac(Bn)CuOiPr: a strained geometry resulting in very high lactide polymerization activity | Chemical communications (Cambridge, England) |
| 23016983 | 2012-10-24 | Tandem metal-coordination copolymerization and organocatalytic ring-opening polymerization via water to synthesize diblock copolymers of styrene oxide/CO2 and lactide | Journal of the American Chemical Society |
| 23009063 | 2012-10-15 | Stereoselective synthesis of biphenolate/binaphtolate titanate and zirconate alkoxide species: structural characterization and use in the controlled ROP of lactide | Inorganic chemistry |
| 23030249 | 2012-10-15 | Synthesis and characterization of amine-bridged bis(phenolate)lanthanide alkoxides and their application in the controlled polymerization of rac-lactide and rac-β-butyrolactone | Inorganic chemistry |
| 22903466 | 2012-10-14 | Dimethylaluminium aldiminophenolates: synthesis, characterization and ring-opening polymerization behavior towards lactides | Dalton transactions (Cambridge, England : 2003) |
| 22561339 | 2012-10-10 | Dual-purpose magnetic micelles for MRI and gene delivery | Journal of controlled release : official journal of the Controlled Release Society |
| 22930321 | 2012-10-09 | Highly heteroselective ring-opening polymerization of racemic lactide initiated by divalent ytterbium complexes bearing amino bis(phenolate) ligands | Chemical communications (Cambridge, England) |
| 22892614 | 2012-10-07 | Al and Zn complexes bearing N,N,N-tridentate quinolinyl anilido-imine ligands: synthesis, characterization and catalysis in L-lactide polymerization | Dalton transactions (Cambridge, England : 2003) |
