PLGA scaffold, short for poly(lactic-co-glycolic acid) scaffold, is a biodegradable material composed of polylactic acid (PLA) and polyglycolic acid (PGA) copolymerized in specific ratios. Owing to its excellent biocompatibility, controllable degradability, and mechanical strength, PLGA has been widely applied in tissue engineering, drug delivery, and regenerative medicine. In tissue engineering, scaffolds play a crucial role by mimicking the three-dimensional structure of the extracellular matrix (ECM), providing support for cell adhesion, proliferation, and differentiation, while enabling nutrient and waste exchange. By adjusting the PLA/PGA ratio, molecular weight, and fabrication process, PLGA scaffolds can be customized to exhibit different pore structures and degradation rates, meeting the diverse requirements of tissue engineering. BOC Sciences is dedicated to providing high-quality PLGA scaffold preparation and custom development services for research institutions, pharmaceutical companies, and biomaterials enterprises. Our one-stop solutions encompass material selection, fabrication process design, and functional modification. We focus on addressing customer needs in tissue engineering, drug-controlled release, biomimetic scaffold design, and customized functionalization, ensuring that every PLGA scaffold achieves optimal standards in structure, porosity, mechanical properties, and degradation performance. Through precise control of the lactic/glycolic acid ratio, molecular weight, and microstructure, we deliver personalized scaffold materials tailored to both research and production applications.
With extensive experience and professional expertise, BOC Sciences offers a comprehensive range of PLGA scaffolds—from basic porous scaffolds to functional composite scaffolds. Whether for bone tissue, soft tissue, or drug carrier applications, we can tailor pore structures, mechanical properties, and functional characteristics to provide reliable support for scientific and industrial research.
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BOC Sciences offers comprehensive PLGA scaffold development services that integrate polymer chemistry, materials engineering, and drug delivery technologies, providing end-to-end solutions from molecular design to functional applications. Whether for research studies, controlled drug release, or complex tissue engineering, we deliver efficient and reliable technical support.
Equipped with advanced analytical instruments and an experienced technical team, BOC Sciences provides comprehensive PLGA scaffold characterization services. Our analyses cover multiple dimensions—from raw material properties and scaffold structure to functional performance—ensuring optimal quality in porosity, mechanical strength, degradation rate, and drug release behavior to support high-standard research and industrial applications.
| Test Category | Test Item | Description / Purpose |
|---|---|---|
| Chemical Characterization | FTIR (Fourier Transform Infrared Spectroscopy) | Verify PLGA chemical structure, functional groups, and success of functional modifications. |
| NMR (Nuclear Magnetic Resonance) | Determine lactic acid/glycolic acid ratio, polymer structure, and end-group modifications. | |
| GPC (Gel Permeation Chromatography) | Measure molecular weight and distribution, evaluate polymer uniformity and degradation properties. | |
| Physical Structure Analysis | SEM (Scanning Electron Microscopy) | Observe scaffold surface microstructure, pore morphology, and fiber arrangement. |
| Micro-CT (Micro-Computed Tomography) | 3D reconstruction of pore structure, quantitative analysis of porosity, pore size, and connectivity. | |
| DSC (Differential Scanning Calorimetry) | Analyze polymer thermal properties, glass transition temperature, and crystallinity. | |
| Mechanical Testing | Compression/Tensile Testing | Measure scaffold mechanical strength, elastic modulus, and deformation characteristics to ensure structural stability. |
| Degradation and Swelling Performance | Hydrolytic Degradation Test | Determine scaffold degradation rate and mass changes in simulated physiological environment. |
| Swelling Ratio Test | Evaluate pore water absorption capacity and structural stability. | |
| Drug Release and Functional Analysis | Drug Release Profile | Assess release rate and mechanism of drugs embedded in the scaffold. |
| Bioactivity Evaluation | Measure scaffold support for cell adhesion, proliferation, or differentiation. | |
| Surface Characterization | Contact Angle Measurement | Evaluate surface hydrophilicity and cell adhesion potential. |
| XPS (X-ray Photoelectron Spectroscopy) | Analyze surface elemental composition and chemical modifications. |
BOC Sciences provides an end-to-end development process that covers every stage—from requirement communication, material selection, and formulation design to scaffold fabrication, functionalization, and performance evaluation. Our workflow ensures optimal porosity, mechanical properties, and degradation behavior while supporting advanced features such as drug-controlled release and surface modification. This enables us to deliver efficient, customizable solutions for both research and industrial applications.
We work closely with clients to discuss application objectives, tissue types, pore size requirements, and functionalization needs for PLGA scaffolds. Comprehensive project background analysis and professional technical consultation are provided to ensure a scientifically sound development direction.
Based on application needs, we determine the appropriate PLA/PGA ratio, molecular weight, and scaffold type. Pore structure, mechanical properties, and drug-loading schemes are optimized to achieve ideal degradation rates, strength, and biocompatibility, ensuring a solid foundation for functional development.
Using techniques such as solvent casting, phase separation, freeze-drying, electrospinning, and 3D printing, we achieve precise 3D scaffold fabrication. Nanofiber processing and composite material preparation can also be applied to meet various tissue engineering and biomimetic material requirements.
We provide drug encapsulation, surface modification, and composite material preparation services according to customer specifications. Smart-responsive scaffolds can be designed to react to pH, temperature, or enzymatic stimuli, achieving controlled degradation and drug release for complex tissue engineering and controlled-release applications.
We evaluate porosity, pore size, mechanical strength, and degradation rate to ensure structural stability and reliability. Drug-loaded scaffolds undergo release profile testing and functional performance evaluation to ensure controlled drug release, reproducible performance, and compliance with scientific and industrial standards.
Customized PLGA scaffolds and detailed technical reports are delivered, ensuring transparency and traceability for each batch. Continuous R&D support and optimization recommendations are provided to help clients achieve the best experimental or industrial outcomes and ensure efficient project advancement.
Due to its excellent biodegradability, biocompatibility, and tunable structural properties, PLGA scaffolds have become a central platform in biomimetic material and tissue engineering research. BOC Sciences offers highly customizable PLGA scaffolds designed to meet various requirements in tissue type, pore structure, mechanical strength, and functionalization. Our scaffolds support bone, cartilage, and soft tissue repair, as well as stem cell culture, drug-controlled release, localized therapy, and in vitro tissue model construction.
A PLGA scaffold is a biodegradable material made from poly(lactic acid) (PLA) and poly(glycolic acid) (PGA) copolymers. It is widely used in tissue engineering and biomimetic material research, featuring excellent biocompatibility, controllable degradation, and tunable structure to support cell growth, tissue repair, and drug-controlled release applications.
PLGA scaffolds are extensively used in bone, cartilage, skin, vascular, and neural tissue engineering. They are also suitable for stem cell culture, in vitro tissue model construction, controlled drug release, and smart biomimetic material development, providing reliable support for research and preclinical studies.
By adjusting the lactic/glycolic acid ratio, molecular weight, fabrication technique, and processing parameters, pore size, porosity, and mechanical strength can be precisely controlled. BOC Sciences offers fabrication technologies such as 3D printing, freeze-drying, and electrospinning to meet various tissue engineering requirements.
Yes. PLGA scaffolds can be loaded with anticancer drugs, antibiotics, or growth factors for sustained and controlled local release. The release rate can be precisely regulated through material composition, scaffold pore structure, and composite functionalization to meet different therapeutic and research needs.
Yes. PLGA scaffolds can undergo surface modification, bioactivation, or composite material integration, such as coating with collagen, gelatin, or nanomaterials. Functionalized scaffolds enhance cell adhesion and differentiation capabilities and can be designed with smart-responsive behavior for dynamic control and precise drug release.
BOC Sciences implements full-process quality control, including chemical characterization (FTIR, NMR, GPC), physical structure analysis (SEM, Micro-CT), mechanical testing, degradation assessment, and drug release evaluation. Each batch is accompanied by detailed technical reports to ensure stable, reproducible performance that meets research and industrial standards.
