1,4-Dioxan-2,5-dione
Product Information
Molecular Formula
C4H4O4
Molecular Weight
116.07
Description
Synthesis of biodegradable homo- and copolymers
Synonyms
2,5-dioxo-1,4-dioxane; Acetic acid, hydroxy-, bimol. cyclic ester; Glycollide; p-Dioxane-2,5-dione; GLYCOLIDE; GLYCOLIDE A
IUPAC Name
1,4-dioxane-2,5-dione
SMILES
C1C(=O)OCC(=O)O1
InChI
InChI=1S/C4H4O4/c5-3-1-7-4(6)2-8-3/h1-2H2
InChI Key
RKDVKSZUMVYZHH-UHFFFAOYSA-N
Boiling Point
322.5°C at 760 mmHg
Melting Point
81-83°C
Purity
95%
Density
1.423 g/cm3
Appearance
white crystalline solid
Storage
-20°C
Refractive Index
1.4500 (estimate)
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
-0.2
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
116.01095860 g/mol
Monoisotopic Mass
116.01095860 g/mol
Topological Polar Surface Area
52.6Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
112
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113827783-A | Preparation method of highly oriented composite material for artificial bone | 2021-03-02 |
| CN-112280026-A | Semi-aromatic polyester and preparation method and application thereof | 2020-12-31 |
| CN-112280026-B | Semi-aromatic polyester and preparation method and application thereof | 2020-12-31 |
| CN-112456917-A | High-durability concrete and preparation method thereof | 2020-12-09 |
| EP-3932986-A1 | A thermoplastic composition having improved mechanical properties | 2020-07-03 |
| WO-2022003170-A1 | A thermoplastic composition having improved mechanical properties | 2020-07-03 |
| JP-2021172738-A | Resin composition, emitter, and drip irrigation tube | 2020-04-24 |
| WO-2021215250-A1 | Resin composition, emitter, and tube for drip irrigation | 2020-04-24 |
| WO-2021216807-A1 | Biodegradable copolymers and nanofibrous scaffold thereof | 2020-04-23 |
| WO-2021204783-A1 | Compositions based on silane-functional polymers having enhanced overpaintability | 2020-04-08 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 20602152 | 2010-09-01 | Hydrophilic polyester microspheres: effect of molecular weight and copolymer composition on release of BSA | Pharmaceutical research |
| 20690705 | 2010-08-09 | Organo-catalyzed ring opening polymerization of a 1,4-dioxane-2,5-dione deriving from glutamic acid | Biomacromolecules |
