4,4'-Biphenol
Product Information
Molecular Formula
C12H10O2
Molecular Weight
186.21
Description
Used in the preparation of polyether liquid crystals.
Synonyms
(1,1'-Biphenyl)-4,4'-diol; [1,1'-biphenyl]-4,4'-diol; [1,1'-Biphenyl]-4,4'-diol; 4,4'-bisphenol; 4,4'-Dihydroxy-1,1'-biphenyl; 4,4'-Dioxydiphenyl; Antioxidant DOD; antioxidantdod
IUPAC Name
4-(4-hydroxyphenyl)phenol
SMILES
C1=CC(=CC=C1C2=CC=C(C=C2)O)O
InChI
InChI=1S/C12H10O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8,13-14H
InChI Key
VCCBEIPGXKNHFW-UHFFFAOYSA-N
Boiling Point
355.2°C at 760 mmHg
Melting Point
278-283°C
Flash Point
176.1°C
Purity
99%
Density
1.228 g/cm3
Appearance
Powder
Application
Used to make plastics and as a laboratory reagent.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Stability
Stable under normal temperatures and pressures.
Vapor Pressure
0.00000079 [mmHg]
Safety Information
Hazards
H312:
Harmful in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H411:
Toxic to aquatic life with long-lasting effects.
Harmful in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H411:
Toxic to aquatic life with long-lasting effects.
Precautionary Statement
P264:
Wash thoroughly after handling.
P273:
Avoid release to the environment.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P391:
Collect spillage.
Wash thoroughly after handling.
P273:
Avoid release to the environment.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P391:
Collect spillage.
Computed Properties
XLogP3
3.6
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
1
Exact Mass
186.068079557 g/mol
Monoisotopic Mass
186.068079557 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
145
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114149580-A | Rigid twisted microporous polymer-sulfonated polyether sulfone porous composite membrane and preparation method and application thereof | 2022-01-12 |
| CN-114181046-A | Preparation method of 4,4' -biphenol with low energy consumption | 2021-12-27 |
| CN-114181052-A | Preparation method of high-purity 4, 4' -biphenol | 2021-12-20 |
| CN-114031484-A | Method for synthesizing 4, 4' -biphenol | 2021-12-09 |
| CN-114057788-A | Preparation method of high-purity 4, 4' -biphenol bis (di (2, 6-dimethylphenyl) phosphate) | 2021-12-08 |
| CN-113881045-A | Synthetic method for stably improving impact strength of polyether sulfone | 2021-12-07 |
| CN-113881045-B | Synthetic method for stably improving impact strength of polyether sulfone | 2021-12-07 |
| CN-114171790-A | Liquid crystal polymer electrolyte and lithium secondary battery comprising same | 2021-12-02 |
| CN-113980431-A | High-performance liquid crystal polymer film material and preparation method thereof | 2021-12-01 |
| CN-114014749-A | 4-hydroxy biphenyl derivatives, preparation method and application | 2021-11-23 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 27259399 | 2016-07-15 | Synthesis and evaluation of biphenyl derivatives as potential downregulators of VEGF protein secretion and telomerase-related gene expressions | Bioorganic & medicinal chemistry |
| 24266771 | 2013-12-12 | Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists | Journal of medicinal chemistry |
| 22160344 | 2012-08-01 | Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp | Marine biotechnology (New York, N.Y.) |
| 22515182 | 2012-05-04 | Polyphosphoric acid promoted synthesis of 10,11-dihydrobenzo[j]fluoranthen-12-one | Organic letters |
| 22085246 | 2011-12-19 | Hydrogen-bonded inclusion compounds with reversed polarity: anionic metal-complexes and cationic organic linkers | Inorganic chemistry |
| 22087767 | 2011-12-19 | Overoxidation of phenol by hexachloroiridate(IV) | Inorganic chemistry |
| 21626582 | 2011-07-11 | Unidirectional redox-stimulated movement around a C-C single bond | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 21256504 | 2011-04-01 | Preparation of perfluoro-1,3-propanedisulfonic acid/silica nanocomposites-encapsulated low molecular weight aromatic compounds possessing a nonflammable characteristic | Journal of colloid and interface science |
| 21413891 | 2011-03-01 | Development of single-stranded DNA aptamers for specific Bisphenol a detection | Oligonucleotides |
| 21522331 | 2011-02-05 | 4,4'-Bis[(E)-(2,3-diiodo-prop-2-en-1-yl)-oxy]biphen-yl | Acta crystallographica. Section E, Structure reports online |
