4,4'-Biphenol

Product Information

Molecular Formula:
C12H10O2
Molecular Weight:
186.21
Description
Used in the preparation of polyether liquid crystals.
Synonyms
(1,1'-Biphenyl)-4,4'-diol; [1,1'-biphenyl]-4,4'-diol; [1,1'-Biphenyl]-4,4'-diol; 4,4'-bisphenol; 4,4'-Dihydroxy-1,1'-biphenyl; 4,4'-Dioxydiphenyl; Antioxidant DOD; antioxidantdod
IUPAC Name
4-(4-hydroxyphenyl)phenol
Canonical SMILES
C1=CC(=CC=C1C2=CC=C(C=C2)O)O
InChI
InChI=1S/C12H10O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8,13-14H
InChI Key
VCCBEIPGXKNHFW-UHFFFAOYSA-N
Boiling Point
355.2°C at 760 mmHg
Melting Point
278-283°C
Flash Point
176.1°C
Purity
99%
Density
1.228 g/cm3
Appearance
Powder
Application
Used to make plastics and as a laboratory reagent.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Stability
Stable under normal temperatures and pressures.
Vapor Pressure
0.00000079 [mmHg]

Safety Information

Hazards
H312:
Harmful in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H411:
Toxic to aquatic life with long-lasting effects.
Precautionary Statement
P264:
Wash thoroughly after handling.
P273:
Avoid release to the environment.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P391:
Collect spillage.

Computed Properties

XLogP3
3.6
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
1
Exact Mass
186.068079557 g/mol
Monoisotopic Mass
186.068079557 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
145
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114149580-A Rigid twisted microporous polymer-sulfonated polyether sulfone porous composite membrane and preparation method and application thereof 2022-01-12
CN-114181046-A Preparation method of 4,4' -biphenol with low energy consumption 2021-12-27
CN-114181052-A Preparation method of high-purity 4, 4' -biphenol 2021-12-20
CN-114031484-A Method for synthesizing 4, 4' -biphenol 2021-12-09
CN-114057788-A Preparation method of high-purity 4, 4' -biphenol bis (di (2, 6-dimethylphenyl) phosphate) 2021-12-08
CN-113881045-A Synthetic method for stably improving impact strength of polyether sulfone 2021-12-07
CN-113881045-B Synthetic method for stably improving impact strength of polyether sulfone 2021-12-07
CN-114171790-A Liquid crystal polymer electrolyte and lithium secondary battery comprising same 2021-12-02
CN-113980431-A High-performance liquid crystal polymer film material and preparation method thereof 2021-12-01
CN-114014749-A 4-hydroxy biphenyl derivatives, preparation method and application 2021-11-23

Literatures

PMID Publication Date Title Journal
27259399 2016-07-15 Synthesis and evaluation of biphenyl derivatives as potential downregulators of VEGF protein secretion and telomerase-related gene expressions Bioorganic & medicinal chemistry
24266771 2013-12-12 Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists Journal of medicinal chemistry
22160344 2012-08-01 Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp Marine biotechnology (New York, N.Y.)
22515182 2012-05-04 Polyphosphoric acid promoted synthesis of 10,11-dihydrobenzo[j]fluoranthen-12-one Organic letters
22085246 2011-12-19 Hydrogen-bonded inclusion compounds with reversed polarity: anionic metal-complexes and cationic organic linkers Inorganic chemistry
22087767 2011-12-19 Overoxidation of phenol by hexachloroiridate(IV) Inorganic chemistry
21626582 2011-07-11 Unidirectional redox-stimulated movement around a C-C single bond Chemistry (Weinheim an der Bergstrasse, Germany)
21256504 2011-04-01 Preparation of perfluoro-1,3-propanedisulfonic acid/silica nanocomposites-encapsulated low molecular weight aromatic compounds possessing a nonflammable characteristic Journal of colloid and interface science
21413891 2011-03-01 Development of single-stranded DNA aptamers for specific Bisphenol a detection Oligonucleotides
21522331 2011-02-05 4,4'-Bis[(E)-(2,3-diiodo-prop-2-en-1-yl)-oxy]biphen-yl Acta crystallographica. Section E, Structure reports online
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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