4-(DIPHENYLPHOSPHINO)BENZOIC ACID
Product Information
Molecular Formula
C19H15O2P
Molecular Weight
306.29
Description
4-(Diphenylphosphino)benzoic acid is a potential compound for drug discovery and development in cancer, diabetes and cardiovascular disease.
Synonyms
4-(DIPHENYLPHOSPHINO)BENZOIC ACID
IUPAC Name
4-diphenylphosphanylbenzoic acid
SMILES
C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=C(C=C3)C(=O)O
InChI
InChI=1S/C19H15O2P/c20-19(21)15-11-13-18(14-12-15)22(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14H,(H,20,21)
InChI Key
GXMHDTPYKRTARV-UHFFFAOYSA-N
Melting Point
157-160 °C (lit.)
Purity
>97.0%(T)
Appearance
White to yellow powder or crystals
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Computed Properties
XLogP3
5.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
4
Exact Mass
306.08096671 g/mol
Monoisotopic Mass
306.08096671 g/mol
Topological Polar Surface Area
37.3Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
332
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113663715-A | P-doped g-C3N4Sheet photocatalyst and preparation method and application thereof | 2021-09-23 |
| CN-113751719-A | Glutathione-lighted non-sulfhydryl gold nanomaterial and preparation method and application thereof | 2021-08-27 |
| CN-112679327-A | Method for preparing aldehyde compound by olefin two-phase hydroformylation | 2021-01-12 |
| CN-112679327-B | Method for preparing aldehyde compound by olefin two-phase hydroformylation | 2021-01-12 |
| WO-2022009930-A1 | Light-emitting material, light-emitting ink, light-emitting body, and light-emitting device | 2020-07-10 |
| CN-111606792-A | Method for preparing high-carbon aldehyde | 2020-06-29 |
| US-2021408383-A1 | Fabricating Organic Light Emitting Diodes (OLEDs) Using Tubulin | 2020-06-25 |
| CN-110981710-A | Method for synthesizing methyl heptenone from isoprene | 2019-11-26 |
| KR-102128261-B1 | Preparation of water-soluble acryl-modified phenol-modified epoxy resin, water-soluble acryl-modified phenol-modified epoxy resin preparedthereby, and aqueous paint composition comprising the same | 2019-10-15 |
| WO-2021075800-A1 | Method for preparing water-soluble acrylic-modified phenolic-modified epoxy resin, water-soluble acrylic-modified phenolic-modified epoxy resin prepared thereby, and aqueous coating composition comprising same | 2019-10-15 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22059022 | 2011-09-01 | 4-(Diphenyl-phosphan-yl)benzoic acid | Acta crystallographica. Section E, Structure reports online |
| 21580939 | 2008-10-04 | 4-(Diphenyl-phosphino-yl)benzoic acid | Acta crystallographica. Section E, Structure reports online |
| 15664802 | 2005-02-01 | Hybridization dependent cleavage of internally modified disulfide-peptide nucleic acids | Bioorganic & medicinal chemistry letters |
| 14871070 | 2004-02-18 | Supramolecular catalysts by encapsulating palladium complexes within dendrimers | Journal of the American Chemical Society |
| 14719913 | 2004-01-21 | A new solvent system for recycling catalysts for chelation-assisted hydroacylation of olefins with primary alcohols | Journal of the American Chemical Society |
| 12667706 | 2003-04-01 | Synthesis and characterization of new copper(I) complexes containing 4-(diphenylphosphane)benzoic acid and 'scorpionate' ligands with 'in vitro' superoxide scavenging activity | Journal of inorganic biochemistry |
