4-(DIPHENYLPHOSPHINO)BENZOIC ACID

Product Information

Molecular Formula:
C19H15O2P
Molecular Weight:
306.29
Description
4-(Diphenylphosphino)benzoic acid is a potential compound for drug discovery and development in cancer, diabetes and cardiovascular disease.
Synonyms
4-(DIPHENYLPHOSPHINO)BENZOIC ACID
IUPAC Name
4-diphenylphosphanylbenzoic acid
Canonical SMILES
C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=C(C=C3)C(=O)O
InChI
InChI=1S/C19H15O2P/c20-19(21)15-11-13-18(14-12-15)22(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14H,(H,20,21)
InChI Key
GXMHDTPYKRTARV-UHFFFAOYSA-N
Melting Point
157-160 °C (lit.)
Purity
>97.0%(T)
Appearance
White to yellow powder or crystals

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338

Computed Properties

XLogP3
5.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
4
Exact Mass
306.08096671 g/mol
Monoisotopic Mass
306.08096671 g/mol
Topological Polar Surface Area
37.3Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
332
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113663715-A P-doped g-C3N4Sheet photocatalyst and preparation method and application thereof 2021-09-23
CN-113751719-A Glutathione-lighted non-sulfhydryl gold nanomaterial and preparation method and application thereof 2021-08-27
CN-112679327-A Method for preparing aldehyde compound by olefin two-phase hydroformylation 2021-01-12
CN-112679327-B Method for preparing aldehyde compound by olefin two-phase hydroformylation 2021-01-12
WO-2022009930-A1 Light-emitting material, light-emitting ink, light-emitting body, and light-emitting device 2020-07-10
CN-111606792-A Method for preparing high-carbon aldehyde 2020-06-29
US-2021408383-A1 Fabricating Organic Light Emitting Diodes (OLEDs) Using Tubulin 2020-06-25
CN-110981710-A Method for synthesizing methyl heptenone from isoprene 2019-11-26
KR-102128261-B1 Preparation of water-soluble acryl-modified phenol-modified epoxy resin, water-soluble acryl-modified phenol-modified epoxy resin preparedthereby, and aqueous paint composition comprising the same 2019-10-15
WO-2021075800-A1 Method for preparing water-soluble acrylic-modified phenolic-modified epoxy resin, water-soluble acrylic-modified phenolic-modified epoxy resin prepared thereby, and aqueous coating composition comprising same 2019-10-15

Literatures

PMID Publication Date Title Journal
22059022 2011-09-01 4-(Diphenyl-phosphan-yl)benzoic acid Acta crystallographica. Section E, Structure reports online
21580939 2008-10-04 4-(Diphenyl-phosphino-yl)benzoic acid Acta crystallographica. Section E, Structure reports online
15664802 2005-02-01 Hybridization dependent cleavage of internally modified disulfide-peptide nucleic acids Bioorganic & medicinal chemistry letters
14871070 2004-02-18 Supramolecular catalysts by encapsulating palladium complexes within dendrimers Journal of the American Chemical Society
14719913 2004-01-21 A new solvent system for recycling catalysts for chelation-assisted hydroacylation of olefins with primary alcohols Journal of the American Chemical Society
12667706 2003-04-01 Synthesis and characterization of new copper(I) complexes containing 4-(diphenylphosphane)benzoic acid and 'scorpionate' ligands with 'in vitro' superoxide scavenging activity Journal of inorganic biochemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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