(+)-Camphor
Product Information
Molecular Formula
C10H16O
Molecular Weight
152.23
Description
(+)-Camphor is a terpenoid used as a culinary flavoring agent in parts of Asia. It has insecticidal activity and is also used as an antimicrobial agent.
Synonyms
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R,4R)-; Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)-; Camphor, (1R,4R)-(+)-; (+)-(1R,4R)-Camphor; (+)-2-Bornanone; (1R)-(+)-Camphor; (1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one; (1R)-Camphor; (1R,4R)-(+)-Camphor; (R)-(+)-Camphor; (R)-Camphor; D-(+)-Camphor; D-Camphor; Alcanfor; Camphor, (+)-; d-Camphor; Dextrocamphora; Japanese camphor
IUPAC Name
(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
SMILES
CC1(C2CCC1(C(=O)C2)C)C
InChI
1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1
InChI Key
DSSYKIVIOFKYAU-XCBNKYQSSA-N
Boiling Point
207.4°C
Melting Point
178.8°C
Flash Point
64°C
Purity
≥98%
Density
0.982±0.06 g/cm3
Solubility
Soluble in Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
Appearance
White Sticky Solid
Shelf Life
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage
Store at -20°C
Stability
Stable. Incompatible with strong reducing agents, strong oxidizing agents, chlorinated solvents. Protect from direct sunlight.
LogP
2.380
Vapor Pressure
1 mmHg at 106.7 °F
Related CAS
68546-28-1 (Deleted CAS)
Safety Information
Hazards
H228:
Flammable solid.
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Flammable solid.
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P210:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P370+P378:
In case of fire:
Use for extinction:
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P370+P378:
In case of fire:
Use for extinction:
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Computed Properties
XLogP3
2.2
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
152.120115130 g/mol
Monoisotopic Mass
152.120115130 g/mol
Topological Polar Surface Area
17.1Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
217
Isotope Atom Count
0
Defined Atom Stereocenter Count
2
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113648387-A | Plant extract for repairing beta islet cells and reducing blood glucose, and preparation method and application thereof | 2021-08-20 |
| CN-113318121-A | Medicine for treating diabetic retinopathy and preparation method thereof | 2021-06-23 |
| CN-113018355-A | Auxiliary external application medicine for thoracic cavity tumor and abdominal cavity tumor and using method thereof | 2021-03-16 |
| RU-2750161-C1 | Method for producing d-camphor anils | 2020-12-11 |
| CN-213886317-U | Camphor powder stoving reducing mechanism | 2020-12-08 |
| CN-112358757-A | Strippable protective film coating and preparation method and application thereof | 2020-10-26 |
| US-10912753-B1 | Topical skin care composition | 2020-10-20 |
| CN-112618676-A | Application of gynura segetum and extract thereof in preparing medicine for treating and/or preventing vascular endothelial injury | 2020-10-10 |
| US-11033516-B1 | Combination therapies with disulfiram | 2020-09-18 |
| WO-2022054917-A1 | Mouth-coating feel enhancer | 2020-09-11 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 31702924 | 2020-01-09 | Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic | Journal of medicinal chemistry |
| 22461383 | 2012-08-01 | Quantitative structure-activity relationships of monoterpenoid binding activities to the housefly GABA receptor | Pest management science |
| 21162008 | 2010-12-01 | Chemical variations of the essential oils in flower heads of Chrysanthemum indicum L. from China | Chemistry & biodiversity |
| 20565070 | 2010-07-23 | An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds | Journal of natural products |
| 20356305 | 2010-07-22 | Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents | Journal of medicinal chemistry |
| 17684094 | 2007-08-14 | 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1 | Proceedings of the National Academy of Sciences of the United States of America |
| 16939314 | 2006-09-06 | Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils | Journal of agricultural and food chemistry |
| 15646539 | 2004-08-01 | [Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs] | Gastroenterologie clinique et biologique |
| 15161226 | 2004-06-02 | chemical composition, plant genetic differences, antimicrobial and antifungal activity investigation of the essential oil of Rosmarinus officinalis L | Journal of agricultural and food chemistry |
| 12444669 | 2002-11-01 | Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay | Journal of natural products |
