Poly(D,L-lactide-co-glycolide)

Catalog Number Size Price Stock Quantity
B2697-011136 10 g $298 In stock
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Product Information

Molecular Formula:
(C3H4O2)x(C2H2O2)y
Description
Poly(D,L-lactide-co-glycolide) is used for macromolecular therapeutic delivery. Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid can enhance the level of toxin-neutralizing antibodies.
Synonyms
Purasorb(R) PDLG; Poly(D,L-lactide-co-glycolide); Poly(DL-lactide-co-glycolide) (50:50); Poly(DL-lactide-co-glycolide) (85:15); Poly(DL-lactide/glycolide); DL-lactide/glycolide copolymer; LACTEL BP-0100; LACTEL BP-0200
IUPAC Name
3,6-dimethyl-1,4-dioxane-2,5-dione1,4-dioxane-2,5-dione
Canonical SMILES
CC1C(=O)OC(C(=O)O1)C.C1C(=O)OCC(=O)O1
InChI
InChI=1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-35-3-1-7-4(6)2-8-3/h3-4H,1-2H31-2H2
InChI Key
LCSKNASZPVZHEG-UHFFFAOYSA-N
Storage
Protect from moisture. Store at -20°C

Safety Information

Hazards
Irritant. Hygroscopic
Handling
Exercise normal care

QC Data

Molecular WeightViscosityDescription
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 50:50 IV 0.40 dl/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 50:50 IV 0.6 dl/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 50:50 IV 1.0 dl/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 70:30 IV 0.2 dl/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 75:25 IV 0.65 dl/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 80:20 IV 0.2 dl/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 85:15 IV 0.85 dL/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).
Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 90:10 IV 0.2 dl/g Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).

Computed Properties

Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
0
Exact Mass
260.05321734 g/mol
Monoisotopic Mass
260.05321734 g/mol
Topological Polar Surface Area
105Ų
Heavy Atom Count
18
Formal Charge
0
Complexity
267
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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