Poly(D,L-lactide-co-glycolide)
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-011136 | 10 g | $298 | In stock |
Product Information
Molecular Formula
(C3H4O2)x(C2H2O2)y
Description
Poly(D,L-lactide-co-glycolide) is used for macromolecular therapeutic delivery. Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid can enhance the level of toxin-neutralizing antibodies.
Synonyms
Purasorb(R) PDLG; Poly(D,L-lactide-co-glycolide); Poly(DL-lactide-co-glycolide) (50:50); Poly(DL-lactide-co-glycolide) (85:15); Poly(DL-lactide/glycolide); DL-lactide/glycolide copolymer; LACTEL BP-0100; LACTEL BP-0200
IUPAC Name
3,6-dimethyl-1,4-dioxane-2,5-dione1,4-dioxane-2,5-dione
SMILES
CC1C(=O)OC(C(=O)O1)C.C1C(=O)OCC(=O)O1
InChI
InChI=1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-35-3-1-7-4(6)2-8-3/h3-4H,1-2H31-2H2
InChI Key
LCSKNASZPVZHEG-UHFFFAOYSA-N
Storage
Protect from moisture. Store at -20°C
Safety Information
Hazards
Irritant. Hygroscopic
Handling
Exercise normal care
QC Data
| Molecular Weight | Viscosity | Description |
|---|---|---|
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 50:50 | IV 0.40 dl/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 50:50 | IV 0.6 dl/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 50:50 | IV 1.0 dl/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 70:30 | IV 0.2 dl/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 75:25 | IV 0.65 dl/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 80:20 | IV 0.2 dl/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 85:15 | IV 0.85 dL/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
| Mw~ <10,000, Poly(D.L-lactide) : Poly(glycolide) = 90:10 | IV 0.2 dl/g | Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content). |
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
0
Exact Mass
260.05321734 g/mol
Monoisotopic Mass
260.05321734 g/mol
Topological Polar Surface Area
105Ų
Heavy Atom Count
18
Formal Charge
0
Complexity
267
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
