C12E5

Product Information

Molecular Formula:
C22H46O6
Molecular Weight:
406.60
Description
C12E5 acts as a non-ionic surfactant and can be used to extract membrane proteins, such as fusion protein and haemagglutinin neuraminidase of the Sendai virus.
Synonyms
Pentaethylene glycol monododecyl ether; Dodecyl pentaethylene glycolether; n-Dodecylpentaoxyethylene; Laureth-5; Pentaethylene glycol lauryl ether; Pentaoxyethylene monododecyl ether; Polyoxyethylene (5) lauryl ether; PEG-5 Lauryl ether; 3,6,9,12,15-Pentaoxaheptacosan-1-ol
IUPAC Name
2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol
Canonical SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCO
InChI
InChI=1S/C22H46O6/c1-2-3-4-5-6-7-8-9-10-11-13-24-15-17-26-19-21-28-22-20-27-18-16-25-14-12-23/h23H,2-22H2,1H3
InChI Key
LAPRIVJANDLWOK-UHFFFAOYSA-N
Boiling Point
486.6±35.0°C at 760 mmHg
Melting Point
14.5-15.0°C
Flash Point
248.1°C
Purity
≥95%
Density
0.963 g/mL at 20°C
Appearance
White to Light yellow powder to lump
Application
Non-ionic surfactant.
Storage
Store at -20°C
Stability
Stable. Flammable. Incompatible with strong oxidizing agents.

Computed Properties

XLogP3
4.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
25
Exact Mass
406.32943918 g/mol
Monoisotopic Mass
406.32943918 g/mol
Topological Polar Surface Area
66.4Ų
Heavy Atom Count
28
Formal Charge
0
Complexity
265
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113768846-A Nourishing anti-dandruff shampoo and preparation method thereof 2021-10-26
KR-102313788-B1 Detergent Composition for removing Scale and Rust of Heat Exchanger 2021-08-31
EP-3818972-A2 Piroctone olamine granules for use in cosmetic compositions 2021-01-29
KR-102242940-B1 Method for preparing a non-reducing cleaning composition containing vegetable extracts and a non-reducing cleaning composition prepared thereby 2021-01-19
CN-112587454-A Anti-allergic oriental cherry refreshing shampoo and preparation method thereof 2020-12-23
WO-2022056484-A1 Method of treating amyloidosis 2020-09-14
US-2022071857-A1 Dissolvable solid article containing anti-bacterial actives 2020-09-10
WO-2022053140-A1 Surfactant containing formulation of pseudo-ceramides 2020-09-10
WO-2022056524-A1 Dissolvable solid article containing anti-bacterial actives 2020-09-10
WO-2022053784-A1 Crystalline form iii of tetraacetylethylenediamine 2020-09-09

Literatures

PMID Publication Date Title Journal
21981373 2011-12-06 Sphere-to-rod transitions of nonionic surfactant micelles in aqueous solution modeled by molecular dynamics simulations Langmuir : the ACS journal of surfaces and colloids
18825291 2008-10-21 Segmental order parameters in a nonionic surfactant lamellar phase studied with 1H-13C solid-state NMR Physical chemistry chemical physics : PCCP
18307365 2008-04-01 Phase behavior and microstructure of C12E5 nonionic microemulsions with chlorinated oils Langmuir : the ACS journal of surfaces and colloids
17979395 2007-10-28 Effect of cholesterol on diffusion in surfactant bilayers The Journal of chemical physics
17302467 2007-02-07 Atomic force microscopy images of lyotropic lamellar phases The Journal of chemical physics
16293237 2006-01-01 Thermotropic phase behaviour of the pseudobinary mixtures of DPPC/C12E5 and DMPC/C12E5 determined by differential scanning calorimetry and ultrasonic velocimetry Chemistry and physics of lipids
15450466 2004-10-15 Study of mixtures of n-dodecyl-beta-D-maltoside with anionic, cationic, and nonionic surfactant in aqueous solutions using surface tension and fluorescence techniques Journal of colloid and interface science
14724754 2003-11-01 The Ca(2+)-ATPase of the scallop sarcoplasmic reticulum is of a cold-adapted type The Journal of membrane biology
12755586 2003-05-01 Structure elucidation, synthesis, and contact allergenic activity of a major hydroperoxide formed at autoxidation of the ethoxylated surfactant C12E5 Chemical research in toxicology
12484925 2002-12-16 Topological transition in aqueous nonionic micellar solutions Physical review letters
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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