C12E5
Product Information
Molecular Formula
C22H46O6
Molecular Weight
406.60
Description
C12E5 acts as a non-ionic surfactant and can be used to extract membrane proteins, such as fusion protein and haemagglutinin neuraminidase of the Sendai virus.
Synonyms
Pentaethylene glycol monododecyl ether; Dodecyl pentaethylene glycolether; n-Dodecylpentaoxyethylene; Laureth-5; Pentaethylene glycol lauryl ether; Pentaoxyethylene monododecyl ether; Polyoxyethylene (5) lauryl ether; PEG-5 Lauryl ether; 3,6,9,12,15-Pentaoxaheptacosan-1-ol
IUPAC Name
2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol
SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCO
InChI
InChI=1S/C22H46O6/c1-2-3-4-5-6-7-8-9-10-11-13-24-15-17-26-19-21-28-22-20-27-18-16-25-14-12-23/h23H,2-22H2,1H3
InChI Key
LAPRIVJANDLWOK-UHFFFAOYSA-N
Boiling Point
486.6±35.0°C at 760 mmHg
Melting Point
14.5-15.0°C
Flash Point
248.1°C
Purity
≥95%
Density
0.963 g/mL at 20°C
Appearance
White to Light yellow powder to lump
Application
Non-ionic surfactant.
Storage
Store at -20°C
Stability
Stable. Flammable. Incompatible with strong oxidizing agents.
Computed Properties
XLogP3
4.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
25
Exact Mass
406.32943918 g/mol
Monoisotopic Mass
406.32943918 g/mol
Topological Polar Surface Area
66.4Ų
Heavy Atom Count
28
Formal Charge
0
Complexity
265
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113768846-A | Nourishing anti-dandruff shampoo and preparation method thereof | 2021-10-26 |
| KR-102313788-B1 | Detergent Composition for removing Scale and Rust of Heat Exchanger | 2021-08-31 |
| EP-3818972-A2 | Piroctone olamine granules for use in cosmetic compositions | 2021-01-29 |
| KR-102242940-B1 | Method for preparing a non-reducing cleaning composition containing vegetable extracts and a non-reducing cleaning composition prepared thereby | 2021-01-19 |
| CN-112587454-A | Anti-allergic oriental cherry refreshing shampoo and preparation method thereof | 2020-12-23 |
| WO-2022056484-A1 | Method of treating amyloidosis | 2020-09-14 |
| US-2022071857-A1 | Dissolvable solid article containing anti-bacterial actives | 2020-09-10 |
| WO-2022053140-A1 | Surfactant containing formulation of pseudo-ceramides | 2020-09-10 |
| WO-2022056524-A1 | Dissolvable solid article containing anti-bacterial actives | 2020-09-10 |
| WO-2022053784-A1 | Crystalline form iii of tetraacetylethylenediamine | 2020-09-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21981373 | 2011-12-06 | Sphere-to-rod transitions of nonionic surfactant micelles in aqueous solution modeled by molecular dynamics simulations | Langmuir : the ACS journal of surfaces and colloids |
| 18825291 | 2008-10-21 | Segmental order parameters in a nonionic surfactant lamellar phase studied with 1H-13C solid-state NMR | Physical chemistry chemical physics : PCCP |
| 18307365 | 2008-04-01 | Phase behavior and microstructure of C12E5 nonionic microemulsions with chlorinated oils | Langmuir : the ACS journal of surfaces and colloids |
| 17979395 | 2007-10-28 | Effect of cholesterol on diffusion in surfactant bilayers | The Journal of chemical physics |
| 17302467 | 2007-02-07 | Atomic force microscopy images of lyotropic lamellar phases | The Journal of chemical physics |
| 16293237 | 2006-01-01 | Thermotropic phase behaviour of the pseudobinary mixtures of DPPC/C12E5 and DMPC/C12E5 determined by differential scanning calorimetry and ultrasonic velocimetry | Chemistry and physics of lipids |
| 15450466 | 2004-10-15 | Study of mixtures of n-dodecyl-beta-D-maltoside with anionic, cationic, and nonionic surfactant in aqueous solutions using surface tension and fluorescence techniques | Journal of colloid and interface science |
| 14724754 | 2003-11-01 | The Ca(2+)-ATPase of the scallop sarcoplasmic reticulum is of a cold-adapted type | The Journal of membrane biology |
| 12755586 | 2003-05-01 | Structure elucidation, synthesis, and contact allergenic activity of a major hydroperoxide formed at autoxidation of the ethoxylated surfactant C12E5 | Chemical research in toxicology |
| 12484925 | 2002-12-16 | Topological transition in aqueous nonionic micellar solutions | Physical review letters |
