Bis[(dicyclohexyl)(4-dimethylaminophenyl)phosphine] palladium(II) chloride
Product Information
Molecular Formula
(CH3)2NC6H4P(C6H11)2PdCl2P(C6H4N(CH3)2)(C6H11)2
Molecular Weight
812.22
Description
Bis[(dicyclohexyl)(4-dimethylaminophenyl)phosphine] palladium(II) chloride is a powerful catalyst widely used in the biomedical industry. It plays a crucial role in various organic transformations, including Suzuki-Miyaura cross-coupling reactions. This product is essential for the synthesis of pharmaceutical drugs, such as antineoplastic agents and antiviral compounds, and contributes to the treatment of cancer, viral infections, and other diseases.
Synonyms
(A-caPhos)2 PdCl2
IUPAC Name
dichloropalladium4-dicyclohexylphosphanyl-N,N-dimethylaniline
SMILES
CN(C)C1=CC=C(C=C1)P(C2CCCCC2)C3CCCCC3.CN(C)C1=CC=C(C=C1)P(C2CCCCC2)C3CCCCC3.Cl[Pd]Cl
InChI
InChI=1S/2C20H32NP.2ClH.Pd/c2*1-21(2)17-13-15-20(16-14-17)22(18-9-5-3-6-10-18)19-11-7-4-8-12-19/h2*13-16,18-19H,3-12H2,1-2H32*1H/q+2/p-2
InChI Key
FASFJCMBLNNDNL-UHFFFAOYSA-L
Flash Point
Not applicable
Purity
96%
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
8
Exact Mass
810.29566 g/mol
Monoisotopic Mass
810.29566 g/mol
Topological Polar Surface Area
6.5Ų
Heavy Atom Count
47
Formal Charge
0
Complexity
294
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2021062035-A1 | Luminescent materials and methods thereof | 2019-09-27 |
| KR-20200131241-A | 2 kinds of 4-v[(2S)-2-v4-[5-chloro-2-(1H-1,2,3-triazol-1-yl)phenyl]-5-methoxy-2-oxo Method for producing pyridin-1(2H)-yl}butanoyl]amino}-2-fluorobenzamide derivative | 2018-03-15 |
| BR-112020018562-A2 | PREPARATIVE PROCESS | 2018-03-15 |
| US-2021017152-A1 | Preparative process | 2018-03-15 |
| EP-3889147-A1 | 4-({(2s)-2-[4-{5-chloro-2-[4-(trifluoromethyl)-1h-1,2,3-triazol-1-yl]phenyl}-5-methoxy-2-oxopyridin-1(2h)-yl]butanoyl}-amino)-2-fluorobenzamide acetone and its use | 2018-03-15 |
| JP-2021517573-A | Two 4-{[(2S) -2-{4- [5-chloro-2- (1H-1,2,3-triazole-1-yl) phenyl] -5-methoxy-2-oxopyridine-1 Method for preparing (2H) -yl} butanoyl] amino} -2-fluorobenzamide derivative | 2018-03-15 |
| TW-201946915-A | Method and intermediate for preparing therapeutic compound | 2018-02-16 |
| US-10696657-B2 | Methods and intermediates for preparing therapeutic compounds | 2018-02-16 |
| US-2019300505-A1 | Methods and intermediates for preparing therapeutic compounds | 2018-02-16 |
| WO-2019161280-A1 | Methods and intermediates for preparing a therapeutic compound useful in the treatment of retroviridae viral infection | 2018-02-16 |
