2,3-Dimethylmaleic Anhydride

Product Information

Molecular Formula:
C6H6O3
Molecular Weight:
126.11
Description
Applications: 2,3-Dimethylmaleic Anhydride is a reagent used in the synthesis of maleimides and as an amino group protecting agent for superoxide dismutase.
Synonyms
3,4-dimethylfuran-2,5-dione; 3,4-dimethylfuran-2,5-dione
IUPAC Name
3,4-dimethylfuran-2,5-dione
Canonical SMILES
CC1=C(C(=O)OC1=O)C
InChI
InChI=1S/C6H6O3/c1-3-4(2)6(8)9-5(3)7/h1-2H3
InChI Key
MFGALGYVFGDXIX-UHFFFAOYSA-N
Boiling Point
223 °C (lit.)
Melting Point
93-96 °C (lit.)
Flash Point
222-223°C
Purity
98 %
Density
1.107 g/cm3 (100 °C)
Solubility
Very sol in alcohol, Ether, Benzene, Chloroform; slightly sol in water
Appearance
Off-white solid
Application
Used as a research chemical; No known commercial production in the US.
Storage
Refrigerator
Refractive Index
1.5627 (estimate)
LogP
0.40620

Safety Information

Hazards
H302 - H319
Precautionary Statement
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning

Computed Properties

XLogP3
0.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
0
Exact Mass
126.031694049 g/mol
Monoisotopic Mass
126.031694049 g/mol
Topological Polar Surface Area
43.4Ų
Heavy Atom Count
9
Formal Charge
0
Complexity
190
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114057958-A Weak-dispersion early-strength retarder for oil well cement and preparation method thereof 2021-12-29
CN-114149062-A Bactericide for sulfate reducing bacteria in polymer-containing produced liquid and preparation method and application thereof 2021-12-17
CN-114159576-A Preparation method of tumor pH response charge reversal loaded miRNA nano-composite 2021-12-10
CN-114085326-A Graft crosslinking agent, preparation method thereof, impact modifier containing graft crosslinking agent and application of impact modifier 2021-12-06
CN-114057305-A Scale inhibitor slow-release bead, preparation method and application 2021-12-03
JP-2022027821-A Fibrous Cellulose-Containing Compositions and Paints 2021-12-01
CN-114081948-A PH-responsive nanoparticle self-assembled aggregate molecular probe and preparation method and application thereof 2021-11-23
CN-114058664-A N-terminal precise grafting modification method of natural collagen 2021-11-16
CN-113896845-A Low-sensitivity slow-release polycarboxylic slump retaining agent and preparation method thereof 2021-11-01
CN-113861395-A Polyester with acetal group in main chain and preparation method thereof 2021-10-28

Literatures

PMID Publication Date Title Journal
22621748 2012-11-01 Ultrasound assisted copolymerization of acrylonitrile with N-amino phenyl maleimides and N-amino phenyl 2,3 dimethyl maleimides Ultrasonics sonochemistry
22581644 2012-08-01 Charge-conversional poly(amino acid)s derivatives as a drug delivery carrier in response to the tumor environment Journal of biomedical materials research. Part A
22118776 2012-02-01 Doxorubicin-loaded human serum albumin nanoparticles surface-modified with TNF-related apoptosis-inducing ligand and transferrin for targeting multiple tumor types Biomaterials
21772304 2011-08-01 Antifungal activity of tautomycin and related compounds against Sclerotinia sclerotiorum The Journal of antibiotics
20704450 2010-08-20 Short synthesis of the seed germination inhibitor 3,4,5-trimethyl-2(5H)-furanone The Journal of organic chemistry
20298771 2010-06-15 A charge-switched nano-sized polymeric carrier for protein delivery International journal of pharmaceutics
20391548 2010-05-10 A tumor-acidity-activated charge-conversional nanogel as an intelligent vehicle for promoted tumoral-cell uptake and drug delivery Angewandte Chemie (International ed. in English)
19348503 2009-05-01 Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate Molecular pharmaceutics
17628028 2007-09-01 A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential The journal of gene medicine
16753826 2006-04-01 Reversible lipidization for the oral delivery of leu-enkephalin Journal of drug targeting
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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