2-(Di-1-adamantylphosphino)dimethylaminobenzene, 97% Me-DalPhos

Product Information

Molecular Formula:
C28H40NP
Molecular Weight:
421.60
Description
2-(Di-1-adamantylphosphino)dimethylaminobenzene, 97% Me-DalPhos, is a phosphine ligand in biomedical research. It primarily aids in metal-catalyzed reactions, leading to the formation of bioactive molecules. Notably applied in the synthesis of antineoplastic agents targeting cancer cells.
Synonyms
2-[bis(1-adamantyl)phosphanyl]-N,N-dimethylaniline; Me-Dalphos; Di(1-adamantyl)-2-dimethylaminophenylphosphine; 2-(Di-1-adamantylphosphino)dimethylaminobenzene; 1219080-77-9; 2-(Di-1-adamantylphosphino)-N,N-dimethylaniline
IUPAC Name
2-[bis(1-adamantyl)phosphanyl]-N,N-dimethylaniline
Canonical SMILES
CN(C)C1=CC=CC=C1P(C23CC4CC(C2)CC(C4)C3)C56CC7CC(C5)CC(C7)C6
InChI
InChI=1S/C28H40NP/c1-29(2)25-5-3-4-6-26(25)30(27-13-19-7-20(14-27)9-21(8-19)15-27)28-16-22-10-23(17-28)12-24(11-22)18-28/h3-6,19-24H,7-18H2,1-2H3
InChI Key
MILNYLCUWRWYBI-UHFFFAOYSA-N
Melting Point
237-242 °C
Flash Point
Not applicable
Purity
95%

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338

Computed Properties

XLogP3
7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
4
Exact Mass
421.28983728 g/mol
Monoisotopic Mass
421.28983728 g/mol
Topological Polar Surface Area
3.2Ų
Heavy Atom Count
30
Formal Charge
0
Complexity
556
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114105922-A Synthesis method of hydroxypropyl tetrahydropyrane triol 2021-12-03
EP-3771714-A1 Nitrogen-containing heterocycles as pesticides 2019-07-30
WO-2020217733-A1 Method for producing vadadustat intermediate 2019-04-26
CN-113767089-A Preparation method of vatacostat intermediate 2019-04-26
WO-2020152200-A1 Process for preparation of heteroarylketones 2019-01-25
CN-108659534-B Building template material and preparation method thereof 2018-05-23
CN-111534100-A Preparation method of building template material 2018-05-23
CN-111621153-A Adamantyl sulfone based addition polymer building material and application thereof 2018-05-23
JP-2019042708-A Catalyst composition for producing aromatic carboxylic acid or ester thereof from carbon dioxide and aromatic halogen compound, and method for producing aromatic carboxylic acid or ester thereof using the catalyst composition 2017-09-06
JP-6985696-B2 A catalyst composition for producing an aromatic carboxylic acid or an ester thereof from carbon dioxide and an aromatic halogen compound, and a method for producing an aromatic carboxylic acid or an ester thereof using the catalyst composition. 2017-09-06

Literatures

PMID Publication Date Title Journal
20024992 2010-02-08 A highly versatile catalyst system for the cross-coupling of aryl chlorides and amines Chemistry (Weinheim an der Bergstrasse, Germany)
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Online Inquiry
  • Verification code
USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Copyright © 2024 BOC Sciences. All rights reserved.
Top
Inquiry Basket