4-Biphenylboronic acid
Product Information
Molecular Formula
C12H11O2B
Molecular Weight
198.03
Description
4-Biphenylboronic acid is a highly versatile compound that holds immense significance within the biomedical sector as a pivotal pharmaceutical intermediate. Its indispensability lies in aiding the synthesis of an array of drugs intended to combat an extensive range of ailments, including cancer, diabetes, and inflammation.
Synonyms
RARECHEM AH PB 0261; (1,1'-BIPHENYL-4-YL)BORONIC ACID; AKOS BRN-0030; 4-PHENYLBENZENEBORONIC ACID; 4-PHENYLPHENYLBORONIC ACID; 4-BIPHENYLBORONIC ACID
IUPAC Name
(4-phenylphenyl)boronic acid
SMILES
B(C1=CC=C(C=C1)C2=CC=CC=C2)(O)O
InChI
InChI=1S/C12H11BO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,14-15H
InChI Key
XPEIJWZLPWNNOK-UHFFFAOYSA-N
Boiling Point
385.5°C at 760 mmHg
Melting Point
232-245°C
Flash Point
Not applicable
Purity
98%
Density
1.18 g/cm3
Appearance
White to off-white solid
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
2
Exact Mass
198.0852098 g/mol
Monoisotopic Mass
198.0852098 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
182
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113968824-A | 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof | 2021-11-29 |
| CN-114031623-A | C14Amino-substituted tetrandrine derivative and preparation and application thereof | 2021-11-12 |
| CN-114057606-A | Organic luminescent material containing terphenyl, preparation method and application | 2021-11-11 |
| CN-113880714-A | Synthesis method of carbonyl alpha-position monomethyl substituted compound | 2021-09-30 |
| CN-113880854-A | Organic compound containing spiro furocarbazole structure and application thereof | 2021-09-30 |
| CN-113816909-A | Organic electroluminescent material containing phenanthrene structure and device thereof | 2021-09-15 |
| CN-113731504-A | Catalyst and preparation method and application thereof | 2021-09-09 |
| CN-113930790-A | Synthetic method of aryl selenide compound | 2021-09-07 |
| CN-113620901-A | Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof | 2021-08-31 |
| CN-113563590-A | Novel high-temperature-resistant boron-silicon resin and synthetic method thereof | 2021-08-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21580588 | 2010-03-03 | 2-Bromo-p-terphen-yl | Acta crystallographica. Section E, Structure reports online |
| 19731939 | 2009-10-08 | Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors | Journal of medicinal chemistry |
| 18983140 | 2008-11-27 | Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase | Journal of medicinal chemistry |
| 17297238 | 2007-02-01 | Enhancing effect of phenylboronic acid compounds and their interactions with the diol groups of saccharides in a capillary electrophoresis-chemiluminescence detection system | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry |
