P-ANISYLDIPHENYLPHOSPHINE
Product Information
Molecular Formula
C19H17OP
Molecular Weight
292.31
Description
P-ANISYLDIPHENYLPHOSPHINE is a chemical compound used in biomedicine for various applications. It plays a vital role as a ligand in transition metal catalyzed reactions, especially in pharmaceutical synthesis. Additionally, it finds application in the synthesis of drugs targeting various diseases, including cancer and neurological disorders. Its unique properties and versatility make it an essential component in the biomedical industry.
Synonyms
DIPHENYL(2-METHOXYPHENYL)PHOSPHINE; 2-methoxyphenyldiphenylphosphine
IUPAC Name
(2-methoxyphenyl)-diphenylphosphane
SMILES
COC1=CC=CC=C1P(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChI=1S/C19H17OP/c1-20-18-14-8-9-15-19(18)21(16-10-4-2-5-11-16)17-12-6-3-7-13-17/h2-15H,1H3
InChI Key
GBXNVYBGIFEOEM-UHFFFAOYSA-N
Melting Point
124-126 °C (lit.)
Purity
98%
Appearance
White to off-white crystals or crystalline powder
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Computed Properties
XLogP3
4.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
4
Exact Mass
292.101702159 g/mol
Monoisotopic Mass
292.101702159 g/mol
Topological Polar Surface Area
9.2Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
276
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022010858-A1 | Catalyst, redox-switchable catalyst system, and related methods involving hydrosilylation | 2020-07-06 |
| WO-2021219418-A1 | Preparation of aromatic carboxyamides by palladium-catalyzed carbonylation reaction | 2020-04-29 |
| WO-2021219424-A1 | Preparation of aromatic carboxyamides by a palladium-catalyzed carbonylation reaction | 2020-04-29 |
| EP-3888790-A1 | Hydroformylation catalyst system with syngas surrogate | 2020-04-01 |
| WO-2021198113-A1 | Hydroformylation catalyst system with syngas surrogate | 2020-04-01 |
| KR-20210122078-A | Articles exhibiting anti-fouling effect and surface treatment method therefor | 2020-03-31 |
| WO-2021127128-A1 | Two part curable compositions | 2019-12-20 |
| JP-2021046358-A | Regioregular self-doped poly (3,4-ethylenedioxythiophene) derivative and its synthesis method | 2019-09-17 |
| JP-2021046359-A | 2-Hydroxymethyl-2,3-dihydrothieno [3,4-b] [1,4] dioxine-5-carboxylic acid ester | 2019-09-17 |
| JP-2021046361-A | (7-Halo-2,3-dihydrothieno [3,4-b] [1,4] dioxin-2-yl) Methanol | 2019-09-17 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21724304 | 2011-09-01 | Synthesis, characterization and anticancer studies of mixed ligand dithiocarbamate palladium(II) complexes | European journal of medicinal chemistry |
| 21578647 | 2009-11-21 | μ-Bis(diphenyl-arsino)methane-1:2κAs:As-nona-carbonyl-1κC,2κC,3κC-[(2-methoxy-phen-yl)diphenyl-phosphino-3κP]-triangulo-triruthenium(0) | Acta crystallographica. Section E, Structure reports online |
| 21578272 | 2009-10-07 | A redetermination of (2-methoxy-phen-yl)diphenyl-phosphine | Acta crystallographica. Section E, Structure reports online |
| 16212363 | 2005-10-17 | Photophysical properties of Ru(II) bipyridyl complexes containing hemilabile phosphine-ether ligands | Inorganic chemistry |
