P-ANISYLDIPHENYLPHOSPHINE

Product Information

Molecular Formula:
C19H17OP
Molecular Weight:
292.31
Description
P-ANISYLDIPHENYLPHOSPHINE is a chemical compound used in biomedicine for various applications. It plays a vital role as a ligand in transition metal catalyzed reactions, especially in pharmaceutical synthesis. Additionally, it finds application in the synthesis of drugs targeting various diseases, including cancer and neurological disorders. Its unique properties and versatility make it an essential component in the biomedical industry.
Synonyms
DIPHENYL(2-METHOXYPHENYL)PHOSPHINE; 2-methoxyphenyldiphenylphosphine
IUPAC Name
(2-methoxyphenyl)-diphenylphosphane
Canonical SMILES
COC1=CC=CC=C1P(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChI=1S/C19H17OP/c1-20-18-14-8-9-15-19(18)21(16-10-4-2-5-11-16)17-12-6-3-7-13-17/h2-15H,1H3
InChI Key
GBXNVYBGIFEOEM-UHFFFAOYSA-N
Melting Point
124-126 °C (lit.)
Purity
98%
Appearance
White to off-white crystals or crystalline powder

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338

Computed Properties

XLogP3
4.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
4
Exact Mass
292.101702159 g/mol
Monoisotopic Mass
292.101702159 g/mol
Topological Polar Surface Area
9.2Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
276
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
WO-2022010858-A1 Catalyst, redox-switchable catalyst system, and related methods involving hydrosilylation 2020-07-06
WO-2021219418-A1 Preparation of aromatic carboxyamides by palladium-catalyzed carbonylation reaction 2020-04-29
WO-2021219424-A1 Preparation of aromatic carboxyamides by a palladium-catalyzed carbonylation reaction 2020-04-29
EP-3888790-A1 Hydroformylation catalyst system with syngas surrogate 2020-04-01
WO-2021198113-A1 Hydroformylation catalyst system with syngas surrogate 2020-04-01
KR-20210122078-A Articles exhibiting anti-fouling effect and surface treatment method therefor 2020-03-31
WO-2021127128-A1 Two part curable compositions 2019-12-20
JP-2021046358-A Regioregular self-doped poly (3,4-ethylenedioxythiophene) derivative and its synthesis method 2019-09-17
JP-2021046359-A 2-Hydroxymethyl-2,3-dihydrothieno [3,4-b] [1,4] dioxine-5-carboxylic acid ester 2019-09-17
JP-2021046361-A (7-Halo-2,3-dihydrothieno [3,4-b] [1,4] dioxin-2-yl) Methanol 2019-09-17

Literatures

PMID Publication Date Title Journal
21724304 2011-09-01 Synthesis, characterization and anticancer studies of mixed ligand dithiocarbamate palladium(II) complexes European journal of medicinal chemistry
21578647 2009-11-21 μ-Bis(diphenyl-arsino)methane-1:2κAs:As-nona-carbonyl-1κC,2κC,3κC-[(2-methoxy-phen-yl)diphenyl-phosphino-3κP]-triangulo-triruthenium(0) Acta crystallographica. Section E, Structure reports online
21578272 2009-10-07 A redetermination of (2-methoxy-phen-yl)diphenyl-phosphine Acta crystallographica. Section E, Structure reports online
16212363 2005-10-17 Photophysical properties of Ru(II) bipyridyl complexes containing hemilabile phosphine-ether ligands Inorganic chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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