Trimethylvinylsilane
Product Information
Molecular Formula
C5H12Si
Molecular Weight
100.23
Description
Trimethylvinylsilane is a compound used in the biomedical industry for its potential in developing drugs to treat various diseases. It has shown promise as a key building block in the synthesis of pharmaceutical compounds targeting cancer, neurodegenerative disorders, and infectious diseases. Its unique chemical properties make it an essential component in innovative drug discovery and development processes aimed at improving human health.
Synonyms
Trimethylvinylsilane
IUPAC Name
ethenyl(trimethyl)silane
SMILES
C[Si](C)(C)C=C
InChI
InChI=1S/C5H12Si/c1-5-6(2,3)4/h5H,1H2,2-4H3
InChI Key
GCSJLQSCSDMKTP-UHFFFAOYSA-N
Boiling Point
55°C
Melting Point
-132°C
Flash Point
-24 °C
Purity
95%
Density
0.684
Appearance
clear colourless liquid
Application
Used in semiconductor processing.
Storage
Flammables area
Refractive Index
n20/D 1.391 (lit.)
Safety Information
Hazards
H225:
Highly flammable liquid and vapour.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Highly flammable liquid and vapour.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P210:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P233:
Keep container tightly closed.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. [As modified by IV ATP].
Rinse skin with water/shower.
P370+P378:
In case of fire:
Use for extinction:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P233:
Keep container tightly closed.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. [As modified by IV ATP].
Rinse skin with water/shower.
P370+P378:
In case of fire:
Use for extinction:
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
1
Exact Mass
100.070826917 g/mol
Monoisotopic Mass
100.070826917 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
6
Formal Charge
0
Complexity
49.4
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114133905-A | Organic silicon ceramic tile adhesive and preparation method thereof | 2021-12-28 |
| CN-113999395-A | Low-alkoxy polysiloxane and preparation method thereof | 2021-12-14 |
| CN-114182384-A | Method for converting waste mask into regenerated polypropylene fiber | 2021-12-14 |
| CN-113956790-A | Organic silicon coating and preparation method thereof | 2021-12-08 |
| CN-113956776-A | Preparation method of powderable self-repairing flame-retardant low-VOC (volatile organic compound) polyurethane coating and application of powderable self-repairing flame-retardant low-VOC polyurethane coating in automobile leather | 2021-12-06 |
| CN-114108185-A | Preparation method of flame-retardant non-woven fabric and product thereof | 2021-12-03 |
| CN-114133487-A | Modified cellulose-based polymerization surface agent, emulsification viscosity reducer, preparation method of emulsification viscosity reducer and application of emulsification viscosity reducer in viscosity reduction of thick oil | 2021-11-29 |
| CN-113948264-A | Iron-nickel magnetic powder core and preparation method thereof | 2021-11-18 |
| CN-114163841-A | Preparation method and application of polyethylene-coated inorganic particle wear-resistant agent | 2021-11-18 |
| CN-114164674-A | Aerogel thermal fabric and manufacturing method thereof | 2021-11-18 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22834536 | 2012-08-17 | Iron-catalyzed unexpected easy access to stereodefined trimethylsilyl vinyl ketenes | Organic letters |
| 21410167 | 2011-04-15 | (E)-9-(2-iodovinyl)-9H-carbazole: a new coupling reagent for the synthesis of π-conjugated carbazoles | Organic letters |
| 21114294 | 2010-12-22 | Room-temperature regioselective C-H/olefin coupling of aromatic ketones using an activated ruthenium catalyst with a carbonyl ligand and structural elucidation of key intermediates | Journal of the American Chemical Society |
| 20666473 | 2010-08-25 | Development of a general, sequential, ring-closing metathesis/intramolecular cross-coupling reaction for the synthesis of polyunsaturated macrolactones | Journal of the American Chemical Society |
| 20198254 | 2010-03-21 | Cobalt-catalyzed regio- and stereoselective intermolecular enyne coupling: an efficient route to 1,3-diene derivatives | Chemical communications (Cambridge, England) |
| 19609576 | 2010-03-01 | Quantum chemical studies on substitution effects within silyl group in the silylative coupling of olefins | Journal of molecular modeling |
| 19191237 | 2009-01-01 | Palladium-catalyzed cyclopropanation of alkenyl silanes by diazoalkanes: evidence for a Pd(0) mechanism | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 18767837 | 2008-10-01 | Why does fluoride anion accelerate transmetalation between vinylsilane and palladium(II)-vinyl complex? Theoretical study | Journal of the American Chemical Society |
| 18078507 | 2007-12-13 | Part 3. Triethylborane-air: a suitable initiator for intermolecular radical additions of S-2-oxoalkyl-thionocarbonates (S-xanthates) to olefins | Beilstein journal of organic chemistry |
| 17263531 | 2007-02-21 | Scope and mechanism of the intermolecular addition of aromatic aldehydes to olefins catalyzed by Rh(I) olefin complexes | Journal of the American Chemical Society |
