DIMETHYLMALONYL CHLORIDE
Product Information
Molecular Formula
C5H6Cl2O2
Molecular Weight
169.01
Description
DIMETHYLMALONYL CHLORIDE stands as an indispensable mediatory entity involved in the intricate amalgamation of diverse pharmaceuticals. Its utilization primarily encompasses the fabrication of potent antiviral and antimicrobial agents, alongside profound contributions to the expedient synthesis of anticancer medication. Psuedomorphic in nature, this multi-faceted compound assumes a pivotal position in the therapeutic intervention of infectious viral and bacterial maladies, as well as malignant neoplastic pathologies, thus propelling its esteemed significance within the domain of biomedicinal prowess.
Synonyms
DIMETHYLMALONYL CHLORIDE; DIMETHYLMALONYL DICHLORIDE
IUPAC Name
2,2-dimethylpropanedioyl dichloride
SMILES
CC(C)(C(=O)Cl)C(=O)Cl
InChI
InChI=1S/C5H6Cl2O2/c1-5(2,3(6)8)4(7)9/h1-2H3
InChI Key
CJXQAYQWVNXIQE-UHFFFAOYSA-N
Boiling Point
60 °C/10 mmHg (lit.)
Flash Point
123.8 °CF - closed cup
Purity
0.98
Density
1.278
Refractive Index
n20/D 1.451 (lit.)
Safety Information
Hazards
H226 - H314
Precautionary Statement
P280 - P305 + P351 + P338 - P310
Computed Properties
XLogP3
2.4
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
2
Exact Mass
167.9744848 g/mol
Monoisotopic Mass
167.9744848 g/mol
Topological Polar Surface Area
34.1Ų
Heavy Atom Count
9
Formal Charge
0
Complexity
135
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-112500273-A | Preparation method of light stabilizer 2, 2-dibenzoyl propane | 2020-12-03 |
| US-2022048879-A1 | Synthesis of small molecules inspired by Phomoxanthone A | 2020-08-13 |
| WO-2022036040-A1 | Synthesis of small molecules inspired by phomoxanthone a | 2020-08-13 |
| CN-111606868-A | Preparation method of bidentate oxazoline chiral ligand | 2020-06-23 |
| JP-2021195539-A | Thermosetting resin composition | 2020-06-12 |
| JP-2021195537-A | Adhesives, aqueous dispersions and resin modifiers containing modified polyolefins and modified polyolefins | 2020-06-10 |
| WO-2021101606-A1 | Compositions for sunscreen compounds and methods thereof | 2019-11-18 |
| CN-110724112-A | Bisoxazoline ligand compound and synthetic method thereof | 2019-06-28 |
| JP-2020128368-A | Medicine containing an azole-substituted pyridine compound as an active ingredient | 2019-02-08 |
| WO-2020069023-A1 | High-temperature polymer aerogel composites | 2018-09-25 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21589344 | 2010-11-27 | {2,2-Bis[(4S)-4-isopropyl-4,5-dihydro-1,3-oxazol-2-yl]propane}-bis-(N,N-dimethyl-formamide)-copper(II) bis-[hexa-fluoridoanti-monate(V)] | Acta crystallographica. Section E, Structure reports online |
| 21587514 | 2010-09-08 | 2,2'-(Propane-2,2-di-yl)dibenzothia-zole | Acta crystallographica. Section E, Structure reports online |
| 19842700 | 2009-11-11 | An N,N'-diamidocarbene: studies in C-H insertion, reversible carbonylation, and transition-metal coordination chemistry | Journal of the American Chemical Society |
| 21582678 | 2009-06-06 | {2,2-Bis[(4S)-4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl]propane}bis-(N,N-di-methyl-formamide)copper(II) bis-(hexa-fluoridoantimonate) | Acta crystallographica. Section E, Structure reports online |
