2-(2-Methoxyethoxy)acetic acid
Product Information
Molecular Formula
C5H10O4
Molecular Weight
134.13
Description
Applications: 2-(2-Methoxyethoxy)acetic Acid is a urinary metabolite of Diglyme that is a reproductive toxin. 2-(2-Methoxyethoxy)acetic Acid can be used as a biomarker of exposure for jet fuel JP-8 workers.Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package.
Synonyms
TIMTEC-BB SBB008497; 3,6-DIOXAHEPTANOIC ACID; 2-(2-METHOXYETHOXY)ACETIC ACID; (2-methoxyethoxy)acetic acid; 2-(2-METHOXYETHOXY)ACETIC ACID, TECH.; 2-(2-Methoxyethoxy)Acetic; o-(2-methoxyethyl)glycolic acid; (2-Methoxyethoxy)essigsure
IUPAC Name
2-(2-methoxyethoxy)acetic acid
SMILES
COCCOCC(=O)O
InChI
InChI=1S/C5H10O4/c1-8-2-3-9-4-5(6)7/h2-4H2,1H3,(H,6,7)
InChI Key
CLLLODNOQBVIMS-UHFFFAOYSA-N
Boiling Point
245-250°C
Flash Point
356.0 °CF - closed cup
Purity
98%
Density
1.18
Appearance
Colorless Or Straw yellow liquid
Storage
Refrigerator
Refractive Index
n20/D 1.436 (lit.)
Safety Information
Hazards
H314:
Causes severe skin burns and eye damage.
H318:
Causes serious eye damage.
Causes severe skin burns and eye damage.
H318:
Causes serious eye damage.
Precautionary Statement
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P305:
IF IN EYES:
P310:
Immediately call a POISON CENTER or doctor/physician.
P338:
Remove contact lenses if present and easy to do. Continue rinsing.
P351:
Rinse cautiously with water for several minutes.
Wear protective gloves/protective clothing/eye protection/face protection.
P305:
IF IN EYES:
P310:
Immediately call a POISON CENTER or doctor/physician.
P338:
Remove contact lenses if present and easy to do. Continue rinsing.
P351:
Rinse cautiously with water for several minutes.
Computed Properties
XLogP3
-0.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
5
Exact Mass
134.05790880 g/mol
Monoisotopic Mass
134.05790880 g/mol
Topological Polar Surface Area
55.8Ų
Heavy Atom Count
9
Formal Charge
0
Complexity
81
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| KR-102367705-B1 | Solvent-free quantumdot composition, manufacturing method thereof and cured film, color filter and display device using the same | 2021-08-06 |
| CN-113441130-A | Preparation method of metal cation doped titanate aerogel | 2021-06-09 |
| CN-113038734-A | Organic metal solderability preservative, preparation method and application of organic metal solderability preservative film | 2021-03-10 |
| CN-113038734-B | Organic metal solderability preservative, preparation method and application of organic metal solderability preservative film | 2021-03-10 |
| JP-2022041275-A | Manufacturing method of zirconia calcined body | 2020-08-31 |
| WO-2022043813-A1 | Haptic articles and applications using sintered articles prepared from molded gel compositions | 2020-08-27 |
| WO-2022040792-A1 | Piezoceramic pastes with high ceramic content and method for printing same | 2020-08-24 |
| JP-2022033609-A | Metal oxide nanoparticles, compositions containing metal oxide nanoparticles and cured products thereof | 2020-08-17 |
| CN-213434413-U | Equipment for producing 2- (2- (2-methoxyethoxy) ethoxy) acetic acid | 2020-08-15 |
| WO-2022032225-A1 | Grease composition including inorganic fullerene-like particles | 2020-08-07 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22617435 | 2012-09-18 | Detection of DNA damage in workers exposed to JP-8 jet fuel | Mutation research |
| 21809101 | 2012-05-01 | (2-methoxyethoxy)acetic acid: a urinary biomarker of exposure for jet fuel JP-8 | International archives of occupational and environmental health |
| 21705463 | 2012-01-01 | Urinary biomarkers of exposure to glycol ethers and chlorinated solvents during pregnancy: determinants of exposure and comparison with indirect methods of exposure assessment | Occupational and environmental medicine |
| 22712851 | 2012-01-01 | Evaluation and comparison of urinary metabolic biomarkers of exposure for the jet fuel JP-8 | Journal of toxicology and environmental health. Part A |
| 16158298 | 2005-09-01 | Comparison and evaluation of analysis procedures for the quantification of (2-methoxyethoxy)acetic acid in urine | Analytical and bioanalytical chemistry |
| 15705492 | 2005-03-28 | Biomonitoring of 2-(2-alkoxyethoxy)ethanols by analysing urinary 2-(2-alkoxyethoxy)acetic acids | Toxicology letters |
| 20021058 | 2005-01-01 | A Test Procedure for the Determination of (2-Methoxyethoxy)acetic Acid in Urine from Jet Fuel-Exposed Mice | Toxicology mechanisms and methods |
| 12957179 | 2003-09-25 | Procedure for the quantification of the biomarker (2-methoxyethoxy)acetic acid in human urine samples | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences |
