tetrafluorosuccinic acid
Product Information
Molecular Formula
C4H2F4O4
Molecular Weight
190.0499
Description
Tetrafluorosuccinic acid is a powerful reagent widely used in the biomedical industry. It is employed in the synthesis of various pharmaceuticals and agrochemicals. Additionally, it plays a crucial role in the development and manufacturing of drugs used to treat respiratory diseases, cancer, and viral infections.
Synonyms
TETRAFLUORO-1,4-BUTANEDIOIC ACID; TETRAFLUOROSUCCINIC ACID; RARECHEM AL BO 0978; PERFLUOROSUCCINIC ACID; PERFLUORO-1,4-BUTANEDIOIC ACID; Butanedioic acid, tetrafluoro-; Perfluorosuccinate; Succinic acid, perfluoro-
IUPAC Name
2,2,3,3-tetrafluorobutanedioic acid
SMILES
C(=O)(C(C(C(=O)O)(F)F)(F)F)O
InChI
InChI=1S/C4H2F4O4/c5-3(6,1(9)10)4(7,8)2(11)12/h(H,9,10)(H,11,12)
InChI Key
YUDUFRYTKFGQCL-UHFFFAOYSA-N
Boiling Point
150°C 15mm
Melting Point
115-118 °C(lit.)
Flash Point
150°C/15mm
Purity
98%
Density
1,4
Appearance
beige crystalline powder
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
0.7
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
3
Exact Mass
189.98892119 g/mol
Monoisotopic Mass
189.98892119 g/mol
Topological Polar Surface Area
74.6Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
199
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113402702-A | Flame-retardant degradable PBS and preparation method thereof | 2021-07-14 |
| CN-113539686-A | Manufacturing method of anode forming foil of high-specific-volume high-hydration-resistance low-voltage aluminum electrolytic capacitor | 2021-06-29 |
| CN-112852369-A | High-temperature-resistant epoxy adhesive and preparation method thereof | 2021-03-17 |
| CN-112852369-B | High-temperature-resistant epoxy adhesive and preparation method thereof | 2021-03-17 |
| CN-112582176-A | Method for improving specific volume and hydration resistance of low-voltage anodized formed foil of aluminum electrolytic capacitor | 2020-11-10 |
| CN-112582176-B | Method for improving specific volume and hydration resistance of low-voltage anodized formed foil of aluminum electrolytic capacitor | 2020-11-10 |
| CN-112582181-A | Electrolyte for low-voltage aluminum electrolytic capacitor with high hydration resistance and preparation method | 2020-11-10 |
| CN-112582181-B | Electrolyte for low-voltage aluminum electrolytic capacitor with high hydration resistance and preparation method | 2020-11-10 |
| CN-112280511-A | Intelligent slow-bonding prestressed steel strand and preparation method thereof | 2020-10-29 |
| WO-2022054737-A1 | Fluorinated carboxylic acid salt compound | 2020-09-08 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22590105 | 2012-05-01 | catena-Poly[[[tetra-aqua-copper(II)]-μ-4,4'-bipyridyl-κ(2)N:N'] tetra-fluorido-succinate tetra-hydrate] | Acta crystallographica. Section E, Structure reports online |
| 17765602 | 2008-04-01 | Crystal growth of phase matchable new organic nonlinear optical material for UV laser generation | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy |
| 15288138 | 2004-09-01 | Investigation of microenvironmental factors influencing the longitudinal relaxation times of drugs and other compounds | Magnetic resonance imaging |
| 15115392 | 2004-05-06 | Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening | Journal of medicinal chemistry |
| 11551725 | 2001-07-01 | The quantitative 19F-imaging of albumin at 1.5 T: a potential in-vivo tool | Magnetic resonance imaging |
| 11300824 | 2001-03-12 | The simplest supramolecular complexes containing pairs of Mo(2)(formamidinate)(3) units linked with various dicarboxylates: preparative methods, structures, and electrochemistry | Inorganic chemistry |
