L-Proline homopolymer
Product Information
Molecular Formula
(C5H9NO2)x
Molecular Weight
115.13 (monomer)
Description
Proline is an alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2. It has a role as a human metabolite and a Daphnia magna metabolite. It is an alpha-amino acid and a member of pyrrolidines. It is a conjugate base of a prolinium. It is a conjugate acid of a prolinate.
Synonyms
L-Proline, homopolymer; Proline, L-, peptides; 1,2-Pyrrolidinedicarboxylic anhydride, L-, polymers; L-Proline polymer; Poly(L-proline); Polyproline; Proline homopolymer
IUPAC Name
pyrrolidine-2-carboxylic acid
SMILES
C1CC(NC1)C(=O)O
InChI
InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
InChI Key
ONIBWKKTOPOVIA-UHFFFAOYSA-N
Flash Point
Not applicable
Purity
95%
Appearance
White fluffy solid
Storage
Store at -20°C
Related CAS
147-85-3 (monomer) 25191-18-8 (Deleted CAS) 29795-82-2 (Deleted CAS) 29795-83-3 (Deleted CAS) 30705-56-7 (Deleted CAS)
Computed Properties
XLogP3
-2.5
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
115.063328530 g/mol
Monoisotopic Mass
115.063328530 g/mol
Topological Polar Surface Area
49.3Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
103
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2016031879-A1 | Novel indolizine derivatives and their use in neurodegenerative diseases | 2014-07-31 |
| WO-2015086496-A1 | Triazolopyridine derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086498-A1 | Tetrahydroimidazopyridine derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086499-A1 | Imidazopyrimidine derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086501-A1 | Imidazopyridazine derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086502-A1 | Pyrazolopyridine derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086503-A1 | Imidazotriazine derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086504-A1 | Imidazothiazole derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086505-A1 | Purine derivatives as modulators of tnf activity | 2013-12-09 |
| WO-2015086507-A1 | Imidazopyridine derivatives as modulators of tnf activity | 2013-12-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22995066 | 2012-12-15 | Analysis of the phospholipase C-δ1 pleckstrin homology domain using native polyacrylamide gel electrophoresis | Analytical biochemistry |
| 22576701 | 2012-12-01 | Preparation of immunomodulatory hydrolysates from Alaska pollock frame | Journal of the science of food and agriculture |
| 22884961 | 2012-12-01 | Interactive role of nitric oxide and calcium chloride in enhancing tolerance to salt stress | Nitric oxide : biology and chemistry |
| 22885278 | 2012-12-01 | Structural insight into the molecular basis of polyextremophilicity of short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Thermococcus sibiricus | Biochimie |
| 22941249 | 2012-12-01 | Defense responses of soybean roots during exposure to cadmium, excess of nitrogen supply and combinations of these stressors | Molecular biology reports |
| 23007964 | 2012-12-01 | In vitro and in vivo inhibition of human Fanconi anemia-associated head and neck squamous cell carcinoma by a novel nutrient mixture | International journal of oncology |
| 23084901 | 2012-12-01 | Prohormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency | Bioorganic & medicinal chemistry letters |
| 23116672 | 2012-12-01 | An ornithine δ-aminotransferase gene OsOAT confers drought and oxidative stress tolerance in rice | Plant science : an international journal of experimental plant biology |
| 23068764 | 2012-11-23 | Poly-proline-based chiral stationary phases: a molecular dynamics study of triproline, tetraproline, pentaproline and hexaproline interfaces | Journal of chromatography. A |
| 23022414 | 2012-11-15 | Detoxification of Cr(VI) in Salvinia minima is related to seasonal-induced changes of thiols, phenolics and antioxidative enzymes | Journal of hazardous materials |