Carboxymethyl cellulose sodium
Product Information
Molecular Formula
[C6H7O2(OH)x(C2H2O3Na)y]n
Description
Carboxymethyl cellulose sodium is widely used in oral and topical pharmaceutical formulations, mainly because of its viscosity-increasing properties. Carboxymethyl cellulose sodium can also be used as a tablet binder, disintegrant and stabilizing emulsion.
Synonyms
Cellulose, carboxymethyl ether, sodium salt; CM Cellulose; Carmellose; Almelose; Glycolic acid cellulose ether; Carboxymethyl cellulose; Carboxymethyl cellulose ether; Carboxymethyl cellulose sodium salt; Carboxymethylated cellulose sodium salt; Carboxymethylcellulose; Carmacel P-(CC); Carmellose sodium; Cellugel; Cellulose carboxymethylate sodium salt; Cellulose glycolate; Cellulose Gum 9M8; Cellulose sodium glycolate; CM-Cellulose sodium salt; Cepol (polysaccharide); Sodium carboxylatomethyl cellulose; Sodium carboxymethyl cellulose; Sodium carboxymethyl cellulose ether; Sodium carmellose; Sodium cellulose glycolate; Sodium CM-cellulose; Sodium CMC; Sodium glycolate cellulose
Melting Point
>228°C (dec.)
Flash Point
Not applicable
Density
1.59 g/cm3
Solubility
Soluble in Aqueous Acid (Heated, Sonicated, Sparingly), Water (Heated, Sonicated, Sparingly)
Appearance
White or yellowish powder
Application
Used in drilling muds, detergents, resin emulsion paints, adhesives, printing inks, and textile sizes; Also used as a protective colloid, a stabilizer for foods, and a pharmaceutical additive; Used as a bulk laxative, emulsifier and thickener in cosmetics and pharmaceuticals, and stabilizer for reagents; Formerly registered in the US for use as an insecticide for ornamentals and flowering plants; [NPIRS] Permitted for use as an inert ingredient in non-food pesticide products; Used as an anticaking agent, drying agent, emulsifier, formulation aid, humectant, stabilizer or thickener, and texturizer in foods.
Storage
Store at RT
LogP
-4.62260
Related CAS
9004-34-6 (free acid)
Computed Properties
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
5
Exact Mass
262.06646171 g/mol
Monoisotopic Mass
262.06646171 g/mol
Topological Polar Surface Area
158Ų
Heavy Atom Count
17
Formal Charge
0
Complexity
173
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
4
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022034889-A1 | Polysaccharide derivative, polysaccharide derivative-drug conjugate, and method for producing same | 2020-08-14 |
| CN-111676698-B | Modified carbon fiber with composite mechanical interlocking structure interface and composite material thereof | 2020-07-27 |
| WO-2022020761-A1 | Covering assembly with coagulant compartment and uses thereof in a blood monitoring/management system | 2020-07-23 |
| DE-102020209041-A1 | "Means for the treatment of keratin fibers with complexing agent and amino acid and/or protein hydrolyzate" | 2020-07-20 |
| DE-102020207461-A1 | Thickened alkalizing component for oxidative hair lightening agent | 2020-06-17 |
| DE-102020207463-A1 | Thickened alkalizing component for oxidative hair dye | 2020-06-17 |
| WO-2021252761-A2 | Monomeric and oligomeric compound embodiments as contraceptives and therapies and methods of making and using the same | 2020-06-11 |
| WO-2021233242-A1 | Sweetener and flavor compositions containing terpene glycosides | 2020-05-19 |
| WO-2021058074-A1 | Positive particle electrode for a secondary battery and method for producing same from a nanofibre membrane structure | 2019-09-26 |
| WO-2020252522-A1 | Antibacterial dosage regime using cannabinoids | 2019-06-18 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 17629262 | 2007-08-09 | 4-amino-5-substituted-3(2H)-pyridazinones as orally active antinociceptive agents: synthesis and studies on the mechanism of action | Journal of medicinal chemistry |
| 1175 | 1975-12-01 | The effect of splenectomy on the hematology and on the activity of delta-aminolevulinic acid dehydratase (ALA-D) in hemopoietic tissues of the dogfish, Scyliorhinus canicula (Elasmobranchii) | Comparative biochemistry and physiology. A, Comparative physiology |
| 5816 | 1975-01-01 | [Evidence of urinary tubular proteins in inflammatory and toxic kidney damage] | Wiener medizinische Wochenschrift. Supplement |