POLYGLYCINE
Product Information
Molecular Formula
C2H5NO2C2H5NO2C2H5NO2
Description
Polyglycine has been used as an external intensity standard for measuring cross polarization (CP) nuclear magnetic resonance (NMR) spectrum measurements and ion mobility mass spectrometry. It is suitable for use as a model for UV resonance Raman spectroscopy studies.
Synonyms
POLY-L-GLYCINE; POLYGLYCINE; polyglycinemol.wt.5,000-10,000; POLYGLYCINE MOL. WT. 2,000-5,000
IUPAC Name
2-aminoacetic acid
SMILES
C(C(=O)O)N
InChI
InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI Key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
Melting Point
300 °C
Flash Point
Not applicable
Density
1.1607
Solubility
greater than or equal to 100 mg/mL at 64 °F
Appearance
White crystals
Application
A non-essential amino acid that is an inhibitory neurotransmitter; Used as a buffer and reagent in organic chemistry; Used in biochemical research, as a chicken feed additive, to retard rancidity in animal and vegetable oils, as a medication, and nutrient; Used as a flavoring agent and nutritional supplement.
Storage
−20°C
LogP
log Kow = -3.21
Vapor Pressure
0.00000013 [mmHg]
Decomposition
STARTS TO DECOMP AT 233 °C
Dissociation Constants
9.8
Odor
Odorless
Computed Properties
XLogP3
-3.2
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
75.032028402 g/mol
Monoisotopic Mass
75.032028402 g/mol
Topological Polar Surface Area
63.3Ų
Heavy Atom Count
5
Formal Charge
0
Complexity
42.9
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113582891-A | H catalysis with ionic liquid as catalyst2Method for preparing mercaptoalcohol with high additional value by reacting S with epoxy and enol | 2021-03-25 |
| CN-111825703-A | Preparation method of gadobenate dimeglumine injection impurity | 2020-08-04 |
| US-2020405824-A1 | Use of ribonucleotide reductase alone or in combination with micro-dystrophin to treat duchenne muscular dystrophy striated muscle disease | 2019-06-26 |
| WO-2020117942-A1 | Choline metabolism inhibitors | 2018-12-04 |
| EP-3659593-A1 | Trmt2a inhibitors for use in the treatment of polyglutamine diseases | 2018-11-30 |
| WO-2020109233-A2 | Trmt2a inhibitors for use in the treatment of polyglutamine diseases | 2018-11-30 |
| US-2020102356-A1 | Compositions and Methods for the Treatment of Huanglongbing (HLB) aka Citrus Greening in Citrus Plants | 2018-10-01 |
| US-2022053773-A1 | Compositions and methods for the treatment of pathogenic infections in plants | 2018-10-01 |
| US-2020000886-A1 | Engineering the rrm2 subunit of ribonucleotide reductase to resist degradation | 2018-06-29 |
| AU-2019233926-A1 | Method and system for characterization of metabolism-associated conditions, including diagnostics and therapies, based on bioinformatics approach | 2018-03-16 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 36106391 | 2023-01-01 | Exposure to environmental pollutant bisphenol A causes oxidative damage and lipid accumulation in Zebrafish larvae: Protective role of WL15 peptide derived from cysteine and glycine-rich protein 2 | Journal of biochemical and molecular toxicology |
| 36332718 | 2023-01-01 | Comparison of the effect of glyphosate and glyphosate-based herbicide on hippocampal neurogenesis after developmental exposure in rats | Toxicology |
| 35850439 | 2022-10-01 | Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells | Toxicology in vitro : an international journal published in association with BIBRA |
| 35388968 | 2022-08-01 | Glyphosate-based herbicides induces autophagy in IPEC-J2 cells and the intervention of N-acetylcysteine | Environmental toxicology |
| 35485992 | 2022-08-01 | Glyphosate-based herbicide induces long-lasting impairment in neuronal and glial differentiation | Environmental toxicology |
| 35643123 | 2022-07-15 | Glyphosate-based herbicide causes spermatogenesis disorder and spermatozoa damage of the Chinese mitten crab (Eriocheir sinensis) by affecting testes characteristic enzymes, antioxidant capacities and inducing apoptosis | Toxicology and applied pharmacology |
| 35429611 | 2022-06-01 | In vitro toxicity of glyphosate in Atlantic salmon evaluated with a 3D hepatocyte-kidney co-culture model | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association |
| 34964212 | 2022-04-01 | Efficacy of N-acetyl- l-cysteine against glyphosate induced oxidative stress and apoptosis in testicular germ cells preventing infertility | Journal of biochemical and molecular toxicology |
| 35377194 | 2022-04-01 | Association of Glyphosate Exposure with Blood DNA Methylation in a Cross-Sectional Study of Postmenopausal Women | Environmental health perspectives |
| 34850229 | 2022-02-27 | Comparative Toxicogenomics of Glyphosate and Roundup Herbicides by Mammalian Stem Cell-Based Genotoxicity Assays and Molecular Profiling in Sprague-Dawley Rats | Toxicological sciences : an official journal of the Society of Toxicology |
