POLYGLYCINE

Product Information

Molecular Formula:
C2H5NO2C2H5NO2C2H5NO2
Description
Polyglycine has been used as an external intensity standard for measuring cross polarization (CP) nuclear magnetic resonance (NMR) spectrum measurements and ion mobility mass spectrometry. It is suitable for use as a model for UV resonance Raman spectroscopy studies.
Synonyms
POLY-L-GLYCINE; POLYGLYCINE; polyglycinemol.wt.5,000-10,000; POLYGLYCINE MOL. WT. 2,000-5,000
IUPAC Name
2-aminoacetic acid
Canonical SMILES
C(C(=O)O)N
InChI
InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI Key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
Melting Point
300 °C
Flash Point
Not applicable
Density
1.1607
Solubility
greater than or equal to 100 mg/mL at 64 °F
Appearance
White crystals
Application
A non-essential amino acid that is an inhibitory neurotransmitter; Used as a buffer and reagent in organic chemistry; Used in biochemical research, as a chicken feed additive, to retard rancidity in animal and vegetable oils, as a medication, and nutrient; Used as a flavoring agent and nutritional supplement.
Storage
−20°C
LogP
log Kow = -3.21
Vapor Pressure
0.00000013 [mmHg]
Decomposition
STARTS TO DECOMP AT 233 °C
Dissociation Constants
9.8
Odor
Odorless

Computed Properties

XLogP3
-3.2
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
75.032028402 g/mol
Monoisotopic Mass
75.032028402 g/mol
Topological Polar Surface Area
63.3Ų
Heavy Atom Count
5
Formal Charge
0
Complexity
42.9
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113582891-A H catalysis with ionic liquid as catalyst2Method for preparing mercaptoalcohol with high additional value by reacting S with epoxy and enol 2021-03-25
CN-111825703-A Preparation method of gadobenate dimeglumine injection impurity 2020-08-04
US-2020405824-A1 Use of ribonucleotide reductase alone or in combination with micro-dystrophin to treat duchenne muscular dystrophy striated muscle disease 2019-06-26
WO-2020117942-A1 Choline metabolism inhibitors 2018-12-04
EP-3659593-A1 Trmt2a inhibitors for use in the treatment of polyglutamine diseases 2018-11-30
WO-2020109233-A2 Trmt2a inhibitors for use in the treatment of polyglutamine diseases 2018-11-30
US-2020102356-A1 Compositions and Methods for the Treatment of Huanglongbing (HLB) aka Citrus Greening in Citrus Plants 2018-10-01
US-2022053773-A1 Compositions and methods for the treatment of pathogenic infections in plants 2018-10-01
US-2020000886-A1 Engineering the rrm2 subunit of ribonucleotide reductase to resist degradation 2018-06-29
AU-2019233926-A1 Method and system for characterization of metabolism-associated conditions, including diagnostics and therapies, based on bioinformatics approach 2018-03-16

Literatures

PMID Publication Date Title Journal
36106391 2023-01-01 Exposure to environmental pollutant bisphenol A causes oxidative damage and lipid accumulation in Zebrafish larvae: Protective role of WL15 peptide derived from cysteine and glycine-rich protein 2 Journal of biochemical and molecular toxicology
36332718 2023-01-01 Comparison of the effect of glyphosate and glyphosate-based herbicide on hippocampal neurogenesis after developmental exposure in rats Toxicology
35850439 2022-10-01 Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells Toxicology in vitro : an international journal published in association with BIBRA
35388968 2022-08-01 Glyphosate-based herbicides induces autophagy in IPEC-J2 cells and the intervention of N-acetylcysteine Environmental toxicology
35485992 2022-08-01 Glyphosate-based herbicide induces long-lasting impairment in neuronal and glial differentiation Environmental toxicology
35643123 2022-07-15 Glyphosate-based herbicide causes spermatogenesis disorder and spermatozoa damage of the Chinese mitten crab (Eriocheir sinensis) by affecting testes characteristic enzymes, antioxidant capacities and inducing apoptosis Toxicology and applied pharmacology
35429611 2022-06-01 In vitro toxicity of glyphosate in Atlantic salmon evaluated with a 3D hepatocyte-kidney co-culture model Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
34964212 2022-04-01 Efficacy of N-acetyl- l-cysteine against glyphosate induced oxidative stress and apoptosis in testicular germ cells preventing infertility Journal of biochemical and molecular toxicology
35377194 2022-04-01 Association of Glyphosate Exposure with Blood DNA Methylation in a Cross-Sectional Study of Postmenopausal Women Environmental health perspectives
34850229 2022-02-27 Comparative Toxicogenomics of Glyphosate and Roundup Herbicides by Mammalian Stem Cell-Based Genotoxicity Assays and Molecular Profiling in Sprague-Dawley Rats Toxicological sciences : an official journal of the Society of Toxicology
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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