Glatiramer
Product Information
Molecular Formula
(C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2)x
Description
Glatiramer is a synthetic polypeptide immunomodulatory agent that mimics certain properties of myelin basic protein and modulates immune responses involving T cells. It is primarily used in the treatment of relapsing forms of multiple sclerosis and is also widely used in research on neuroimmunology and autoimmune disorders.
Synonyms
L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine; Glutamic acid, L-, peptide with L-alanine, L-lysine and L-tyrosine; Alanine, L-, peptide with L-glutamic acid, L-lysine, and L-tyrosine; Tyrosine, L-, peptide with L-alanine, L-glutamic acid, and L-lysine; L-Alanine, polymer with L-glutamic acid, L-lysine and L-tyrosine; L-Lysine, polymer with L-alanine, L-glutamic acid and L-tyrosine; L-Tyrosine, polymer with L-alanine, L-glutamic acid and L-lysine; Alanine-glutamic acid-lysine-tyrosine polymer; GLAT; L-Alanine-L-glutamic acid-L-lysine-L-tyrosine copolymer; Glatiramir
IUPAC Name
(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2S)-2-aminopentanedioic acid;(2S)-2-aminopropanoic acid;(2S)-2,6-diaminohexanoic acid
SMILES
CC(C(=O)O)N.C1=CC(=CC=C1CC(C(=O)O)N)O.C(CCN)CC(C(=O)O)N.C(CC(=O)O)C(C(=O)O)N
InChI
InChI=1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6)/t8-;5-;3-;2-/m0000/s1
InChI Key
YLOCGHYTXIINAI-XKUOMLDTSA-N
Melting Point
>236°C
Flash Point
Not applicable
Purity
95%
Appearance
White to off-white solid
Storage
Store at 2-8 °C
Computed Properties
Hydrogen Bond Donor Count
11
Hydrogen Bond Acceptor Count
16
Rotatable Bond Count
13
Exact Mass
563.28025714 g/mol
Monoisotopic Mass
563.28025714 g/mol
Topological Polar Surface Area
337Ų
Heavy Atom Count
39
Formal Charge
0
Complexity
488
Isotope Atom Count
0
Defined Atom Stereocenter Count
4
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
4
Compound Is Canonicalized
Yes
