Microcrystalline cellulose
Product Information
Description
Microcrystalline Cellulose, as a renewable and biodegradable polymer, is commmonly used as a structural material. Microcrystalline cellulose is a refined, partially depolymerized cellulose presented as a fine, white powder. As an insoluble polysaccharide, it exhibits exceptional compressibility and stability, making it highly valued in biochemical and analytical applications. Its inert nature and high surface area support its use as a carrier, excipient, and stabilizer in research formulations. Frequently employed in chromatography and sample preparation, microcrystalline cellulose enables efficient separation and purification of biomolecules.
Synonyms
Cellulose; Cellulose 248; Cellulose crystalline
Melting Point
76-78 °C
Flash Point
164°C
Density
1.04 g/cm3 at 20 °C
Solubility
Insoluble in water, ethanol, ether and dilute mineral acids. Slightly soluble in sodium hydroxide solution.
Appearance
White to almost white solid
Application
As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
Storage
Store in a cool, dry place. Store in a tightly closed container. Keep from contact with oxidizing materials.
Refractive Index
n20/D 1.504
Stability
Stable. Combustible. Incompatible with strong oxidizing agents.
Vapor Pressure
0 mm Hg (approx) (NIOSH, 2016);0 mmHg (approx);0 mmHg (approx)
Related CAS
9012-19-5 (Deleted CAS)
Computed Properties
XLogP3
-4.7
Hydrogen Bond Donor Count
8
Hydrogen Bond Acceptor Count
11
Rotatable Bond Count
4
Exact Mass
342.11621151 g/mol
Monoisotopic Mass
342.11621151 g/mol
Topological Polar Surface Area
190Ų
Heavy Atom Count
23
Formal Charge
0
Complexity
382
Isotope Atom Count
0
Defined Atom Stereocenter Count
2
Undefined Atom Stereocenter Count
8
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114106211-A | Yunnan chanterelle polysaccharide and separation and purification method thereof | 2021-08-31 |
| CN-113527716-A | Double-network composite hydrogel with strong chemical performance and preparation method and application thereof | 2021-07-27 |
| CN-113350047-A | Anion sanitary towel | 2021-06-03 |
| CN-113278271-A | Anion chip and anion sanitary towel | 2021-05-28 |
| CN-113135728-A | Gypsum-based decorative mortar and preparation method thereof | 2021-04-25 |
| RU-2759517-C1 | Method for obtaining pharmaceutical sulfated glycoaminoglycans from biological tissues | 2021-04-02 |
| RU-2759517-C9 | Method for obtaining pharmaceutical sulfated glycosaminoglycans from biological tissues | 2021-04-02 |
| CN-112694789-A | Conductive ink for printed electronics | 2020-12-17 |
| CN-112456713-A | Process and equipment for recovering and treating protein in bean product wastewater | 2020-11-24 |
| CN-112220745-A | Magnolia officinalis polysaccharide oral liquid and preparation and application thereof | 2020-09-10 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 29458016 | 2018-03-25 | Renal toxicological evaluations of sulphonated nanocellulose from Khaya sengalensis seed in Wistar rats | Chemico-biological interactions |
| 25735667 | 2015-04-30 | Graphene-oxide stabilization in electrolyte solutions using hydroxyethyl cellulose for drug delivery application | International journal of pharmaceutics |
| 23178343 | 2013-02-01 | Synthesis of peptide-cellulose conjugate mediated by a soluble cellulose derivative having β-Ala esters | International journal of biological macromolecules |
| 23044100 | 2013-01-02 | Characterization of conducting cellulose acetate based polymer electrolytes doped with 'green' ionic mixture | Carbohydrate polymers |
| 23044136 | 2013-01-02 | High production of cellulose degrading endo-1,4-β-D-glucanase using bagasse as a substrate from Bacillus subtilis KIBGE HAS | Carbohydrate polymers |
| 23044140 | 2013-01-02 | Synthesis and photobiocidal properties of cationic porphyrin-grafted paper | Carbohydrate polymers |
| 23044146 | 2013-01-02 | Morphology and thermal properties of PLA-cellulose nanofibers composites | Carbohydrate polymers |
| 23044152 | 2013-01-02 | Carbon nanotube-incorporated multilayered cellulose acetate nanofibers for tissue engineering applications | Carbohydrate polymers |
| 22858801 | 2012-12-15 | Preparation and application of functionalized cellulose acetate/silica composite nanofibrous membrane via electrospinning for Cr(VI) ion removal from aqueous solution | Journal of environmental management |
| 22980788 | 2012-12-15 | Effect of heat treatment on lignification of postharvest bamboo shoots (Phyllostachys praecox f. prevernalis.) | Food chemistry |
