2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone

Product Information

Molecular Formula:
C12H16O4
Molecular Weight:
224.25
Description
4'-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
Synonyms
2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-propanone; 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methylpropan-1-one
IUPAC Name
2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methylpropan-1-one
Canonical SMILES
CC(C)(C(=O)C1=CC=C(C=C1)OCCO)O
InChI
InChI=1S/C12H16O4/c1-12(2,15)11(14)9-3-5-10(6-4-9)16-8-7-13/h3-6,13,15H,7-8H2,1-2H3
InChI Key
GJKGAPPUXSSCFI-UHFFFAOYSA-N
Boiling Point
175 ℃ / 15 mmHg (lit.)
Melting Point
91 ℃
Flash Point
327.2 °F
Purity
98 %
Density
1.183 g/cm3
Appearance
White to light yellow powder to crystal
Storage
Keep in dark place, Sealed in dry, Room Temperature
Refractive Index
n20/D 1.475 (lit.)
LogP
1.01130

Safety Information

Hazards
H411
Precautionary Statement
P273

Computed Properties

XLogP3
0.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
5
Exact Mass
224.10485899 g/mol
Monoisotopic Mass
224.10485899 g/mol
Topological Polar Surface Area
66.8Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
229
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

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CN-114082310-A Roll type membrane element and preparation method and application thereof 2022-01-20
CN-114058040-A Preparation method of 3D hydrogel for cell amplification culture, product and application thereof 2021-12-28
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CN-113980189-A Polyester acrylic acid weather-resistant pressure-sensitive adhesive and preparation method thereof 2021-12-17
CN-114177369-A Blocking anti-adhesion membrane material and preparation method thereof 2021-12-17
CN-114149717-A Hydrogel function modified coating and preparation method thereof 2021-12-16
JP-2022040133-A A photosensitive coloring composition for a color filter for a solid-state image sensor, a color filter, and a solid-state image sensor using the same. 2021-12-15
CN-114163550-A Multifunctional macromolecular photoinitiator and preparation method thereof 2021-12-14
CN-114164201-A Preparation method of immobilized cellulase with temperature-pH dual responsiveness 2021-12-13
CN-113968936-A Tough chitosan hydrogel and preparation method and application thereof 2021-12-09

Literatures

PMID Publication Date Title Journal
22767528 2012-07-16 Systematic studies of UV stability and photopolymerization efficiency of DNA-based nanomaterials Chemphyschem : a European journal of chemical physics and physical chemistry
22215075 2011-12-16 Tracking hypoxic signaling within encapsulated cell aggregates Journal of visualized experiments : JoVE
21871915 2011-12-01 Photocrosslinkable biodegradable responsive hydrogels as drug delivery systems International journal of biological macromolecules
21232640 2011-05-01 Resorbable elastomeric networks prepared by photocrosslinking of high-molecular-weight poly(trimethylene carbonate) with photoinitiators and poly(trimethylene carbonate) macromers as crosslinking aids Acta biomaterialia
20565511 2010-03-01 Unusual allergic contact dermatitis produced by a transcutaneous electrical nerve stimulator Contact dermatitis
19783300 2009-12-01 Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility Biomaterials
18690661 2009-10-01 Cytocompatibility studies of an in situ photopolymerized thermoresponsive hydrogel nanoparticle system using human aortic smooth muscle cells Journal of biomedical materials research. Part A
18597016 2008-07-21 Direct observation of f-pair magnetic field effects and time-dependence of radical pair composition using rapidly switched magnetic fields and time-resolved infrared methods Physical chemistry chemical physics : PCCP
18065171 2008-03-20 Development of a new photocrosslinkable biodegradable bioadhesive International journal of pharmaceutics
18214758 2008-01-01 UV cross-linked dextran methacrylate--concanavalin A methacrylamide gel materials for self-regulated insulin delivery Drug development and industrial pharmacy
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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