4-Hydroxybenzophenone

Product Information

Molecular Formula:
C13H10O2
Molecular Weight:
198.22
Description
4-Hydroxybenzophenone is a member of benzophenones.
Synonyms
Methanone, (4-hydroxyphenyl)phenyl-; (4-Hydroxyphenyl)phenylmethanone; Benzophenone, 4-hydroxy-; Benzophenone, p-hydroxy-; 1-(4-Hydroxyphenyl)-1-phenylmethanone; 4-Benzoylphenol; 4-Hydroxyphenyl phenyl ketone; 4'-Hydroxybenzophenone; N-(4-Hydroxylphenyl)-N'-phenylurea; NSC 1887; p-Benzoylphenol; p-Hydroxybenzophenone
IUPAC Name
(4-hydroxyphenyl)-phenylmethanone
Canonical SMILES
C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)O
InChI
InChI=1S/C13H10O2/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,14H
InChI Key
NPFYZDNDJHZQKY-UHFFFAOYSA-N
Boiling Point
150-160°C
Melting Point
132-135°C
Flash Point
235.4 °F
Purity
≥95%
Density
1.194±0.06 g/cm3
Solubility
Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
Appearance
white to beige fine crystalline powder
Storage
Store at 2-8°C

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Signal Word
Warning

Computed Properties

XLogP3
3.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
2
Exact Mass
198.068079557 g/mol
Monoisotopic Mass
198.068079557 g/mol
Topological Polar Surface Area
37.3Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
211
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114163550-A Multifunctional macromolecular photoinitiator and preparation method thereof 2021-12-14
CN-114106219-A Nano composite initiator, thickening agent for fracturing fluid and application of thickening agent 2021-12-09
CN-114149311-A Method for preparing 4-hydroxybenzophenone compound by taking p-methylenequinone as substrate 2021-12-08
CN-114106234-A Preparation method and application of ultraviolet-curable acrylic copolymer 2021-11-29
CN-114057790-A Preparation method of vitamin A triphenylphosphine salt with high all-trans isomer content 2021-11-18
CN-113845694-A Modification method of expanded polytetrafluoroethylene, product, proton exchange membrane and membrane electrode 2021-11-12
CN-113881005-A Polymer, preparation method and application thereof, and substrate coated with polymer on surface 2021-11-12
CN-114133334-A Industrial preparation process of tamoxifen citrate 2021-11-09
CN-113773265-A Fluorescent probe for detecting CYP450, preparation method and application thereof 2021-10-25
CN-113912857-A Photochromic coordination polymer and preparation method and application thereof 2021-10-22

Literatures

PMID Publication Date Title Journal
35476924 2022-08-01 4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl1 Toxicology in vitro : an international journal published in association with BIBRA
30245359 2018-12-01 Urinary excretion of phenols, parabens and benzophenones in young men: Associations to reproductive hormones and semen quality are modified by mutations in the Filaggrin gene Environment international
22959206 2012-10-01 Design, synthesis and identification of a new class of triarylmethyl amine compounds as inhibitors of apolipoprotein E production Bioorganic & medicinal chemistry letters
22417702 2012-04-17 Urinary concentrations of benzophenone-type UV filters in U.S. women and their association with endometriosis Environmental science & technology
22452412 2012-04-12 Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein Journal of medicinal chemistry
22334775 2012-01-01 Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells International journal of nanomedicine
21872029 2011-09-30 Determination of benzophenones in human placental tissue samples by liquid chromatography-tandem mass spectrometry Talanta
21530995 2011-08-01 Occurrence of multiclass UV filters in treated sewage sludge from wastewater treatment plants Chemosphere
21480589 2011-05-01 Determination of benzotriazole and benzophenone UV filters in sediment and sewage sludge Environmental science & technology
21853132 2011-01-01 Metabolomics-driven nutraceutical evaluation of diverse green tea cultivars PloS one
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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