Bromomaleic Anhydride

Product Information

Molecular Formula:
C4HBrO3
Molecular Weight:
176.95
Description
Bromomaleic Anhydride (CAS# 5926-51-2) is used to study reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis.
Synonyms
3-bromofuran-2,5-dione; 3-bromofuran-2,5-dione
IUPAC Name
3-bromofuran-2,5-dione
Canonical SMILES
C1=C(C(=O)OC1=O)Br
InChI
InChI=1S/C4HBrO3/c5-2-1-3(6)8-4(2)7/h1H
InChI Key
YPRMWCKXOZFJGF-UHFFFAOYSA-N
Boiling Point
215 °C (lit.)
Flash Point
235.4 °CF - closed cup
Purity
97 %
Density
1.905 g/mL at 25 °C (lit.)
Appearance
Colorless liquid
Refractive Index
n20/D 1.54 (lit.)
LogP
0.34860

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning

Computed Properties

XLogP3
0.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
0
Exact Mass
175.91091 g/mol
Monoisotopic Mass
175.91091 g/mol
Topological Polar Surface Area
43.4Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
182
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114031544-A Substituted maleimide fluorescent compound and preparation and application thereof 2021-10-08
CN-113003981-A Superfine composite mineral admixture grinding aid and preparation method thereof 2021-04-19
JP-2021066746-A Conjugates of cytotoxic agents and cell-binding receptors 2021-02-04
CN-111944134-A Preparation method of high molecular weight unsaturated polyester and product thereof 2020-08-24
CN-111944134-B Preparation method of high molecular weight unsaturated polyester and product thereof 2020-08-24
US-2022048909-A1 Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof 2020-08-14
WO-2022034529-A1 Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof 2020-08-14
WO-2021262830-A1 Silicone elastomer compositions 2020-06-24
CN-111635473-A Method for regulating and controlling product dispersity of reversible addition-fragmentation chain transfer polymerization method 2020-06-17
WO-2021236885-A1 Piperidine-2,6-diones as small molecule degraders of helios and methods of use 2020-05-21

Literatures

PMID Publication Date Title Journal
22095664 2012-01-02 Bromomaleimide-linked bioconjugates are cleavable in mammalian cells Chembiochem : a European journal of chemical biology
20857948 2010-10-15 A colorimetric proton sponge The Journal of organic chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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