Glutaric anhydride

Product Information

Molecular Formula:
C5H6O3
Molecular Weight:
114.1
Description
Glutaric anhydride is a cyclic dicarboxylic anhydride that is oxane which carries oxo groups at positions 2 and 6. It is used as an intermediate in the production of pharmaceuticals, corrosion inhibitors, and polymers (E.g. epoxy polyesters). It is a cyclic dicarboxylic anhydride and a member of oxanes. It is functionally related to a glutaric acid.
Synonyms
2H-Pyran-2,6(3H)-dione,dihydro-; 6(3H)-dione,dihydro-2H-Pyran-2; Anhydrid kyseliny glutarove; anhydridkyselinyglutarove; dihydro-2h-pyran-6(3h)-dione; Glutaric acid anhydride
IUPAC Name
oxane-2,6-dione
Canonical SMILES
C1CC(=O)OC(=O)C1
InChI
InChI=1S/C5H6O3/c6-4-2-1-3-5(7)8-4/h1-3H2
InChI Key
VANNPISTIUFMLH-UHFFFAOYSA-N
Boiling Point
290ºC(570.076 torr)
Melting Point
55-57ºC
Flash Point
347.0 ℃F
Purity
MP 54-56deg
Density
1.24
Appearance
beige to light brown crystalline powder
Application
Used to make fine chemicals.
Storage
2-8ºC

Safety Information

Hazards
H302 - H315 - H318
Precautionary Statement
P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310

Computed Properties

XLogP3
-0.1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
0
Exact Mass
114.031694049 g/mol
Monoisotopic Mass
114.031694049 g/mol
Topological Polar Surface Area
43.4Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
114
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114010798-A Enzymatic self-assembly and disassembly curcumin drug-loaded hydrogel precursor and application thereof 2021-12-27
CN-114181384-A Low-cost, pinhole-resistant and high-hardness polyester resin for HAA system and preparation method thereof 2021-12-20
CN-114106571-A Polymer material for rapidly repairing asphalt pavement cracks and preparation method thereof 2021-12-14
CN-114163547-A Pharmaceutical composition for mild photothermal treatment of tumors and preparation method and application thereof 2021-12-14
CN-114106651-A High-temperature-resistant fluorine-silicon coating and preparation method thereof 2021-12-13
JP-2022027821-A Fibrous Cellulose-Containing Compositions and Paints 2021-12-01
CN-114133466-A Chitosan derivative used for food preservation and preparation method thereof 2021-11-29
CN-114014774-A Fluoroamidone artificial hapten, artificial antigen, and preparation method and application thereof 2021-11-23
CN-113979980-A Preparation method of high-purity butyrolactone 2021-11-22
CN-114133433-A Protein tag, fusion protein or labeled conjugate containing protein tag and application of protein tag 2021-11-22

Literatures

PMID Publication Date Title Journal
22569546 2012-06-14 Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides Chemical communications (Cambridge, England)
22339049 2012-03-02 Catalytic enantioselective desymmetrization of meso-glutaric anhydrides using a stable Ni2-Schiff base catalyst Organic letters
22122759 2012-01-11 Development and application of an indirect competitive enzyme-linked immunosorbent assay for the detection of p,p'-DDE in human milk and comparison of the results against GC-ECD Journal of agricultural and food chemistry
22158441 2011-12-13 Tandem synthesis of alternating polyesters from renewable resources Nature communications
22215983 2011-12-01 Mitotic spindle assembly around RCC1-coated beads in Xenopus egg extracts PLoS biology
21667932 2011-07-18 Macrobicyclic cage amine ligands for copper radiopharmaceuticals: a single bivalent cage amine containing two Lys3-bombesin targeting peptides Inorganic chemistry
22224094 2011-07-01 Development and validation of a rapid HPLC method for simultaneous analysis of budesonide and its novel synthesized hemiesters in colon specific formulations Research in pharmaceutical sciences
21623496 2011-06-01 Design and characterization of a direct ELISA for the detection and quantification of leucomalachite green Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
20429772 2011-02-01 Preparation of budesonide-dextran conjugates using glutarate spacer as a colon-targeted drug delivery system: in vitro/in vivo evaluation in induced ulcerative colitis Journal of drug targeting
22007170 2011-01-01 From understanding cellular function to novel drug discovery: the role of planar patch-clamp array chip technology Frontiers in pharmacology
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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