N-Vinyl-epsilon-caprolactam

Product Information

Molecular Formula:
C8H13NO
Molecular Weight:
139.19
Description
NVCL forms a temperature responsive polymer, which can be used for a variety of biomedical applications.
Synonyms
1-vinylhexahydro-2h-azepin-2-one; 1-ethenylazepan-2-one; 1-Ethenylhexahydro-2H-azepin-2-one; VINYLCAPROLACTAM; N-VINYL-EPSILON-CAPROLACTAM; N-VINYLCAPROLACTAM; 1-ethenylhexahydro-2h-azepin-2-on; 2H-Azepin-2-one, 1-ethenylhexahydro-
IUPAC Name
1-ethenylazepan-2-one
Canonical SMILES
C=CN1CCCCCC1=O
InChI
InChI=1S/C8H13NO/c1-2-9-7-5-3-4-6-8(9)10/h2H,1,3-7H2
InChI Key
JWYVGKFDLWWQJX-UHFFFAOYSA-N
Boiling Point
128 ℃ / 21 mmHg
Melting Point
35-38 ℃
Flash Point
101 ℃ (C.C)
Purity
0.98
Density
1.029
Appearance
solid
Application
Used as an intermediate, in coatings, inks, and toners, as a laboratory reagent, and monomer in polymerization reactions.
Storage
0-10℃
Refractive Index
1

Safety Information

Hazards
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P270:
Do not eat, drink or smoke when using this product.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312+P330:
IF SWALLOWED:
Call a POISON CENTER or doctor/physician if you feel unwell.
Rinse mouth.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.

Computed Properties

XLogP3
1.1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
1
Exact Mass
139.099714038 g/mol
Monoisotopic Mass
139.099714038 g/mol
Topological Polar Surface Area
20.3Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
142
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
JP-2022033262-A Adhesive film 2022-01-04
CN-114181568-A UV ink-jet ink and preparation method thereof 2021-12-31
CN-114057958-A Weak-dispersion early-strength retarder for oil well cement and preparation method thereof 2021-12-29
CN-114149600-A Preparation method and application of temperature-responsive hydrogel 2021-12-27
CN-114149750-A Adhesive, heat-curable adhesive tape, and preparation method and use method thereof 2021-12-14
CN-113956399-A Intelligent composite microgel based on polyvinylpyrrolidone and poly N-vinyl caprolactam as well as preparation method and application thereof 2021-12-10
CN-113956715-A Anti-etching ink for ink-jet printing 2021-12-10
CN-114163566-A Nano-gold-containing polyvinylpyrrolidone/poly-N-vinylcaprolactam hybrid microgel and preparation method thereof 2021-12-10
CN-114015387-A Heat-removable light-cured pressure-sensitive adhesive and preparation method thereof 2021-12-02
CN-114163587-A Nano-silica graft polymer, preparation method and application thereof, and fluid loss additive 2021-11-30

Literatures

PMID Publication Date Title Journal
22888741 2012-10-01 Synthesis and characterization of thermally and glucose-sensitive poly N-vinylcaprolactam-Based microgels Journal of biomedical nanotechnology
22377214 2012-06-01 Metal chelate affinity precipitation: purification of BSA using poly(N-vinylcaprolactam-co-methacrylic acid) copolymers Colloids and surfaces. B, Biointerfaces
21561077 2011-06-07 Synthesis and mass cytometric analysis of lanthanide-encoded polyelectrolyte microgels Langmuir : the ACS journal of surfaces and colloids
21353769 2011-06-01 Optimization of adsorption conditions of BSA on thermosensitive magnetic composite particles using response surface methodology Colloids and surfaces. B, Biointerfaces
21530758 2011-05-01 Effects of N-vinylcaprolactam containing polyelectrolytes on hardness, fluoride release and water sorption of conventional glass ionomers The Journal of prosthetic dentistry
21356411 2011-03-01 Surface properties and bond strength measurements of N-vinylcaprolactam (NVC)-containing glass-ionomer cements The Journal of prosthetic dentistry
21736523 2011-01-01 Poly(N-vinylcaprolactam-co-methacrylic acid) hydrogel microparticles for oral insulin delivery Journal of microencapsulation
20851458 2010-12-01 Measure of microhardness, fracture toughness and flexural strength of N-vinylcaprolactam (NVC)-containing glass-ionomer dental cements Dental materials : official publication of the Academy of Dental Materials
20625836 2010-11-01 Thermoresponsive poly(N-vinylcaprolactam) cryogels: synthesis and its biophysical evaluation for tissue engineering applications Journal of materials science. Materials in medicine
19691278 2009-09-14 Stimuli responsive hydrogels prepared by frontal polymerization Biomacromolecules
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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