Nonoxinol 9

Product Information

Description
Nonoxinol 9, also called as Advantage S or Delfen Cream, belongs to the nonoxynol family of nonionic surfactants.
Synonyms
Advantage S; Advantage-S; Delfen Cream; Delfen Creams; Emulgen 911; Emulgin 913; Mertz Brand of Nonoxinol; Nonoxinol; Nonoxinol Mertz Brand; Nonoxinols; Nonoxy
Boiling Point
Very high
Melting Point
30 °C
Flash Point
470 °F
Density
1.007 at 59 °F
Solubility
Soluble to 45mg/mL in DMSO
Appearance
Colorless or light yellow viscous liquid
Application
Used as a preservative in cleaning products, polishes, antiseptics, hair dyes, spermicides, etc..
Shelf Life
2 years
Storage
Store in a cool and dry place.
Tg
solid or liquid
LogP
log Kow = 4.48 (estimated physical properties based upon 5 ethoxylates)
Vapor Pressure
6.69X10-13 mm Hg at 25 °C (estimated physical properties based upon 5 ethoxylates)
Henry's Law Constant
2.62X10-17 atm-cu m/mol at 25 °C (estimated physical properties based upon 5 ethoxylates)
Decomposition
When heated to decomposition it emits acrid smoke and irritating fumes.

Safety Information

Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H412:
Harmful to aquatic life with long-lasting effects.
Precautionary Statement
P264:
Wash thoroughly after handling.
P273:
Avoid release to the environment.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Molecular WeightDescription
n=approx. 18 White to Almost white wax
n=approx. 5 Colorless to Light yellow clear liquid
n=approx. 20 White to Almost white wax
n=approx. 2 Colorless to Light yellow clear liquid
n=approx. 15

Computed Properties

XLogP3
5.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
11
Exact Mass
264.208930132 g/mol
Monoisotopic Mass
264.208930132 g/mol
Topological Polar Surface Area
29.5Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
186
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
JP-2022031355-A Pest control method 2021-12-15
CN-114085651-A Mine wetting type dust suppressant and preparation method thereof 2021-11-24
JP-2022006186-A Plant disease control method 2021-10-28
JP-2022023190-A Plant disease control method using methyltetraprowl 2021-10-28
CN-114015312-A Laser cutting protection material for bump wafer and preparation method and application thereof 2021-10-26
CN-113910699-A Soft shell outdoor jacket composite fabric and preparation method thereof 2021-10-18
JP-2022001607-A Plant disease control method using phenylpyrazole compound and phenyl compound 2021-10-15
JP-2022006179-A Phytopathogenic microbial control composition 2021-10-15
CN-113617536-A Collecting agent and preparation method and application thereof 2021-09-13
CN-113621445-A Crop straw surface wax wetting and destroying preparation and using method thereof 2021-09-09

Literatures

PMID Publication Date Title Journal
22486240 2012-12-01 Rat sperm immobilisation effects of a protein from Ricinus communis (Linn.): an in vitro comparative study with nonoxynol-9 Andrologia
22494324 2012-11-01 False positives observed on the Seratec® PSA SemiQuant Cassette Test with condom lubricants Journal of forensic sciences
22592833 2012-06-01 Colposcopy: still useful in microbicide safety trials? Sexually transmitted diseases
22705737 2012-06-01 In vitro susceptibility of Staphylococcus aureus strains isolated from cows with subclinical mastitis to different antimicrobial agents Journal of veterinary science
22467453 2012-05-15 Direct analysis in real time mass spectrometry for analysis of sexual assault evidence Rapid communications in mass spectrometry : RCM
22359093 2012-05-01 Detection of the spermicide nonoxynol-9 via GC-MS Journal of the American Society for Mass Spectrometry
22183842 2012-01-01 Acceptability of optical coherence tomography and abstinence requirements among women participating in microbicide safety trials Sexually transmitted diseases
22105265 2011-12-01 Optical coherence tomography compared with colposcopy for assessment of vaginal epithelial damage: a randomized controlled trial Obstetrics and gynecology
22018129 2011-11-01 Mucosal integrity and inflammatory markers in the female lower genital tract as potential screening tools for vaginal microbicides Contraception
21306884 2011-06-15 Spermicidal action of a protein isolated from ethanolic root extracts of Achyranthes aspera: an in vitro study Phytomedicine : international journal of phytotherapy and phytopharmacology
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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