Octaethylene glycol monododecyl ether

Product Information

Molecular Formula:
C28H58O9
Molecular Weight:
538.75
Description
Octaethylene glycol monododecyl ether, a non-ionic surfactant formed by the ethoxylation of dodecanol (lauryl alcohol), is a non-ionic detergent for the solubilization of membrane bound proteins, as well as the viral membranes of intact influenza viruses.
Synonyms
C12E8; 3,6,9,12,15,18,21,24-Octaoxahexatriacontan-1-ol; Dodecyloctaethyleneglycol monoether; N-Dodecyl octaethylene glycol monoether; Octaethylene Glycol Mono-N-Dodecyl Ether
IUPAC Name
2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Canonical SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI
InChI=1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3
InChI Key
YYELLDKEOUKVIQ-UHFFFAOYSA-N
Boiling Point
585.5±45.0°C (Predicted)
Melting Point
30°C
Purity
95%
Density
0.984-0.992 g/mL at 35°C
Solubility
Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance
White to Off-white Low-melting Solid
Storage
Store at RT under inert atmosphere

Computed Properties

XLogP3
4.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
9
Rotatable Bond Count
34
Exact Mass
538.40808342 g/mol
Monoisotopic Mass
538.40808342 g/mol
Topological Polar Surface Area
94.1Ų
Heavy Atom Count
37
Formal Charge
0
Complexity
389
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
KR-102313788-B1 Detergent Composition for removing Scale and Rust of Heat Exchanger 2021-08-31
CN-112245574-A Targeting conveying system loaded with whole-cell components and application thereof 2020-10-23
WO-2022056484-A1 Method of treating amyloidosis 2020-09-14
WO-2022053784-A1 Crystalline form iii of tetraacetylethylenediamine 2020-09-09
WO-2022055840-A1 Flame retardant compositions and methods of use thereof 2020-09-08
US-2022062310-A1 Psilocybin in patients with obsessive-compulsive disorder 2020-09-03
WO-2022051578-A1 Psilocybin in patients with obsessive-compulsive disorder 2020-09-03
US-2022064859-A1 Modified fiber-based materials and methods of making the same 2020-08-28
WO-2022047343-A1 Modified fiber-based materials and methods of making the same 2020-08-28
WO-2022040397-A1 Foamable resin composition for controlling loss circulation 2020-08-19

Literatures

PMID Publication Date Title Journal
21784062 2011-10-01 Characterization of cationic liposomes. Influence of the bilayer composition on the kinetics of the liposome breakdown Chemistry and physics of lipids
21641607 2011-09-01 Characterization of mixed non-ionic surfactants n-octyl-β-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure Journal of colloid and interface science
21284926 2011-06-01 A colorimetric assay for determination of residual detergent levels in reconstituted membrane protein preparations Analytical biochemistry
21352812 2011-03-25 Bulk properties of the lipid bilayer are not essential for the thermal stability of Na,K-ATPase from shark rectal gland or pig kidney Biochemical and biophysical research communications
21909355 2011-01-01 The three-dimensional distribution of αA-crystalline in rat lenses and its possible relation to transparency PloS one
20715782 2010-09-09 Unraveling the Na,K-ATPase alpha(4) subunit assembling induced by large amounts of C(12)E(8) by means of small-angle X-ray scattering The journal of physical chemistry. B
20417021 2010-08-01 Effects of glycerol and urea on micellization, membrane partitioning and solubilization by a non-ionic surfactant Biophysical chemistry
20004176 2010-01-01 Glycyl betaine is effective in slowing down the irreversible denaturation of a detergent-solubilized membrane protein, sarcoplasmic reticulum Ca2+-ATPase (SERCA1a) Biochemical and biophysical research communications
19724139 2009-09-01 Crystallization of mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the specific inhibitor flutolanil Acta crystallographica. Section F, Structural biology and crystallization communications
19961053 2009-09-01 Solubilization and partial characterization of ouabain-insensitive Na(+)-ATPase from basolateral plasma membranes of the intestinal epithelial cells Investigacion clinica
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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