Poly(ethylene glycol) diglycidyl ether
Product Information
Molecular Formula
C3H5O2-(C2H4O)n-C3H5O
Description
Poly(ethylene glycol) diglycidyl ether is an incredibly versatile compound extensively utilized in the biomedical industry. It acts as a pivotal crosslinking agent for synthesizing biofunctional materials and drug delivery systems. With its remarkable reactivity, it empowers the fabrication of hydrogels and coatings, ultimately resulting in the precise and controlled release of medications for targeted therapy. Its wide-ranging application encompasses the effective treatment of several ailments, ranging from cancer and inflammation to cardiovascular disorders, showcasing its immense potential in advancing the field of medicine.
Synonyms
Diepoxy PEG; PEG diglycidyl ether; Polyoxyethylene bis(glycidyl ether)
Storage
Store at 4°C.
Safety Information
Hazards
Irritant
Handling
Gloves & chemical goggles
QC Data
| Molecular Weight | Description |
|---|---|
| Average Mn ~600 | Poly(ethylene glycol) diglycidyl ether (PEGDGE) shows highly solubility in water. Hence, it easily undergoes hydrolysis followed by ring cleavage reaction in aqueous solution, yielding hydroxyl group. PEGDGE combines with proteins covalently or non-covalently. PEGDGE is widely used in chemical industries for cross linking and surface modifier |
| Average Mn ~200 | The high solubility of PEGDGE has been successfully employed to immobilize glucose oxidase, d-amino acid oxidase and glutamate oxidase. It may be used as a component for the development of microelectrode biosensors to detect hydrogen peroxide and nitric oxid |
| Average Mn ~400 | Poly(ethylene glycol) diglycidyl ether (PEGDGE) shows highly solubility in water. Hence, it easily undergoes hydrolysis followed by ring cleavage reaction in aqueous solution, yielding hydroxyl group. PEGDGE combines with proteins covalently or non-covalently. PEGDGE is widely used in chemical industries for cross linking and surface modifier |
| Average Mn ~1000 | Tm is 4-8 ℃.The high solubility of PEGDGE has been successfully employed to immobilize glucose oxidase, d-amino acid oxidase and glutamate oxidase. It may be used as a component for the development of microelectrode biosensors to detect hydrogen peroxide and nitric oxid |
Computed Properties
XLogP3
-0.7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
7
Exact Mass
174.08920892 g/mol
Monoisotopic Mass
174.08920892 g/mol
Topological Polar Surface Area
43.5?2
Heavy Atom Count
12
Formal Charge
0
Complexity
123
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3677244-A2 | Compositions comprising multilamellar vesicles | 2020-02-04 |
| EP-3842469-A1 | Material for forming organic film, method for forming organic film, patterning process, and compound | 2019-12-26 |
| US-2021190718-A1 | Analyte Sensors and Sensing Methods Featuring Low-Potential Detection | 2019-12-23 |
| US-2021190719-A1 | Analyte sensors and sensing methods featuring low-potential detection | 2019-12-23 |
| WO-2021124125-A1 | Process for the preparation of a bonding resin | 2019-12-20 |
| WO-2021124129-A1 | Process for preparing a bonding resin | 2019-12-20 |
| WO-2021124668-A1 | Adhesive composition | 2019-12-20 |
| WO-2021124726-A1 | Fiber-reinforced resin molding material, fiber-reinforced resin molded article, and method for manufacturing fiber-reinforced resin molded article | 2019-12-20 |
| WO-2021124854-A1 | Adhesive sheet | 2019-12-20 |
| WO-2021124855-A1 | Adhesive sheet | 2019-12-20 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21556975 | 2011-06-01 | Extruded collagen fibres for tissue engineering applications: effect of crosslinking method on mechanical and biological properties | Journal of materials science. Materials in medicine |
