Sodium dodecyl sulfate
Product Information
Molecular Formula
C12H25SO4Na
Molecular Weight
288.38
Synonyms
SDS; SLS; K12; Lauryl sulfuric Acid Sodium Salt; Lauryl Sulfate Sodium Salt; Lauryl Sodium Sulfate; Lauryl Sulfate, Sodium; Lauryl Sulfate Na-salt; IPC-SDS; Dodecyl sulfuric Acid Sodium Salt; Dodecyl Sulfate Sodium
IUPAC Name
sodiumdodecyl sulfate
SMILES
CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]
InChI
InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
InChI Key
DBMJMQXJHONAFJ-UHFFFAOYSA-M
Melting Point
204-207 °C(lit.)
Flash Point
>100°C
Purity
>97.0%(GC)(T)
Density
1.03 g/mL at 20 °C
Solubility
less than 1 mg/mL at 66 °F
Appearance
White Powder
Application
SodiumDodecylSulfatecanbeusedasmedicineassistant,fireextinguishingagent,flocculatingagent,textileandleatherassistant,plasticauxiliaries,biocide,andthefoamerfortoothpasteandshampoo,etc.
Storage
Store in shady room and dry place.
Stability
Stable under normal temperatures and pressures.
LogP
4.46490
Decomposition
When heated to decomposition it emits toxic fumes of /sulfur oxides and sodium oxides.
Odor
Faint odor of fatty substances
Related CAS
1334-67-4 (Deleted CAS) 1335-72-4 (Deleted CAS) 8012-56-4 (Deleted CAS) 8048-56-4 (Deleted CAS) 12738-53-3 (Deleted CAS) 12765-21-8 (Deleted CAS) 39384-36-6 (Deleted CAS) 51222-39-0 (Deleted CAS) 57176-54-2 (Deleted CAS) 58640-35-0 (Deleted CAS) 61711-39-5 (Deleted CAS) 64441-33-4 (Deleted CAS) 74433-77-5 (Deleted CAS) 111726-87-5 (Deleted CAS) 121481-64-9 (Deleted CAS) 129203-37-8 (Deleted CAS) 145269-44-9 (Deleted CAS) 152155-52-7 (Deleted CAS) 156108-01-9 (Deleted CAS) 172826-72-1 (Deleted CAS) 191490-40-1 (Deleted CAS) 210297-21-5 (Deleted CAS) 237743-45-2 (Deleted CAS) 303179-49-9 (Deleted CAS) 877454-24-5 (Deleted CAS) 952055-37-7 (Deleted CAS) 952092-90-9 (Deleted CAS) 1000201-72-8 (Deleted CAS) 1000201-73-9 (Deleted CAS) 1357615-49-6 (Deleted CAS) 1883428-81-6 (Deleted CAS) 2326507-32-6 (Deleted CAS)
Safety Information
Hazards
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H335:
May cause respiratory irritation.
H373:
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H335:
May cause respiratory irritation.
H373:
May cause damage to organs through prolonged or repeated exposure.
Precautionary Statement
P260:
Do not breathe dust, fumes, gas, mist, vapours, spray.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340+P312:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
Call a POISON CENTER or doctor/physician if you feel unwell.
P314:
Get medical advice/attention if you feel unwell.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
Do not breathe dust, fumes, gas, mist, vapours, spray.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340+P312:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
Call a POISON CENTER or doctor/physician if you feel unwell.
P314:
Get medical advice/attention if you feel unwell.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
12
Exact Mass
288.13712473 g/mol
Monoisotopic Mass
288.13712473 g/mol
Topological Polar Surface Area
74.8Ų
Heavy Atom Count
18
Formal Charge
0
Complexity
249
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3818972-A2 | Piroctone olamine granules for use in cosmetic compositions | 2021-01-29 |
| US-2021087191-A1 | SUBSTITUTED 3-ISOBUTYL-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-a]ISOQUINOLIN-2-OL COMPOUNDS, THEIR SYNTHESIS, AND USE THEREOF | 2020-12-04 |
| US-11014898-B1 | Benzothiazepine compounds and their use as bile acid modulators | 2020-12-04 |
| US-10981872-B1 | Di(2-aryl hydrozonopropanal) arene derivatives | 2020-10-27 |
| US-10912753-B1 | Topical skin care composition | 2020-10-20 |
| US-2021007978-A1 | Fixed Dose Oral Testosterone Undecanoate Compositions and Use Thereof | 2020-09-25 |
| US-10975102-B1 | Heterocyclic diazenyl pyridinone copper(II) complexes as pharmacological antitumor agents | 2020-09-21 |
| US-11033516-B1 | Combination therapies with disulfiram | 2020-09-18 |
| US-11020349-B1 | Transmucosal dosage forms of remdesivir | 2020-07-14 |
| US-10882852-B1 | 3-vinylquinolines as cancer cells inhibitors | 2020-07-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 33839235 | 2021-08-01 | Influence of silymarin components on keratinocytes and 3D reconstructed epidermis | Toxicology in vitro : an international journal published in association with BIBRA |
| 33715048 | 2021-05-01 | The IL-1 promoter-driven luciferase reporter cell line THP-G1b can efficiently predict skin-sensitising chemicals | Archives of toxicology |
| 33352258 | 2021-03-01 | In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase | Toxicology in vitro : an international journal published in association with BIBRA |
| 33358762 | 2021-03-01 | The EyeIRR-IS assay: Development and evaluation of an in vitro assay to measure the eye irritation sub-categorization of liquid chemicals | Toxicology in vitro : an international journal published in association with BIBRA |
| 31967339 | 2020-05-01 | Effects of hair dye ingredients on the oxidative stress response: Modulation of the mRNA expressions of NRF2, HO-1, and FOS in HaCaT keratinocytes | Contact dermatitis |
| 31734321 | 2020-01-01 | CXCL14 downregulation in human keratinocytes is a potential biomarker for a novel in vitro skin sensitization test | Toxicology and applied pharmacology |
| 31436984 | 2019-09-26 | Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain | Journal of medicinal chemistry |
| 30806763 | 2019-04-01 | The THP-1 cell toolbox: a new concept integrating the key events of skin sensitization | Archives of toxicology |
| 29893927 | 2018-10-01 | Discovery of Ezrin Expression as a Potential Biomarker for Chemically Induced Ocular Irritation Using Human Corneal Epithelium Cell Line and a Reconstructed Human Cornea-like Epithelium Model | Toxicological sciences : an official journal of the Society of Toxicology |
| 29594315 | 2018-06-01 | Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay | Archives of toxicology |
