Tetrafluorohydroquinone
Product Information
Molecular Formula
C6H2F4O2
Molecular Weight
182.07
Description
Tetrafluorohydroquinone is a ubiquitous chemical compound extensively employed in the realm of biomedicine. It assumes a paramount position in the drug development of a myriad of afflictions, encompassing cancer and neurological disorders. By virtue of its formidable attributes as an antioxidant, this potent compound actively facilitates the generation of reactive oxygen species, thereby contributing significantly to the annihilation of malignant cells.
Synonyms
2,3,5,6-Tetrafluorobenzene-1,4-diol,2,3,5,6-Tetrafluorohydroquinone,Tetrafluoro-1,4-dihydroquinone
IUPAC Name
2,3,5,6-tetrafluorobenzene-1,4-diol
SMILES
C1(=C(C(=C(C(=C1F)F)O)F)F)O
InChI
InChI=1S/C6H2F4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11/h11-12H
InChI Key
ZSDAMBJDFDRLSS-UHFFFAOYSA-N
Boiling Point
205.5°C at 760 mmHg
Melting Point
172-174°C(lit.)
Flash Point
78°C
Purity
95%
Density
1.765 g/cm3
Appearance
SLIGHTLY BEIGE CRYSTALLINE POWDER
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
2.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
0
Exact Mass
181.99909195 g/mol
Monoisotopic Mass
181.99909195 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
134
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113831523-A | Low dielectric constant and low dielectric loss liquid crystal polyarylester and composition and film thereof | 2021-11-02 |
| CN-113234193-A | Self-supporting liquid crystal film and preparation method thereof | 2021-05-20 |
| CN-112375010-A | Novel diamine, polyimide and polyimide film | 2020-09-27 |
| CN-111825525-A | Preparation method of tetrafluoro-p-phenylene glycol capable of reducing waste emission | 2020-08-18 |
| WO-2022024073-A1 | Glass containing flame retardant polycarbonate compositions | 2020-07-30 |
| WO-2022000270-A1 | Thermoplastic compositions with improved hydrolytic and heat stability | 2020-06-30 |
| WO-2022003594-A1 | Chemically-resistant flame retardant compositions | 2020-06-30 |
| WO-2022003600-A1 | Scratch-resistant high impact strength pmma compositions | 2020-06-30 |
| JP-2022008153-A | Method for Producing Carboxylate, Carboxylic Acid Generator, Resist Composition and Resist Pattern | 2020-06-25 |
| US-2021403708-A1 | Fiber-Reinforced Polymer Composition | 2020-06-25 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 20603565 | 2010-07-01 | Cocrystals of 2,3,5,6-tetrafluorobenzene-1,4-diol with diaza aromatic compounds | Acta crystallographica. Section C, Crystal structure communications |
| 17665374 | 2007-01-01 | Selective inclusion of electron-donating molecules into porphyrin nanochannels derived from the self-assembly of saddle-distorted, protonated porphyrins and photoinduced electron transfer from guest molecules to porphyrin dications | Chemistry (Weinheim an der Bergstrasse, Germany) |
