Voriconazole EP Impurity E

Product Information

Molecular Formula:
C10H16O4S
Molecular Weight:
232.30
Description
Voriconazole EP Impurity E is an impurity of Voriconazole, which is an antifungal medication used to treat a number of fungal infections.
Synonyms
[(1RS,4SR)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid; (±)-10-Camphorsulfonic acid; Voriconazole Impurity E; Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-; (±)-7,7-Dimethyl-2-oxo-bicyclo[2.2.1]heptane-1-methanesulfonic Acid; (±)-2-Oxo-10-bornanesulfonic Acid; (RS)-10-Camphorsulfonic Acid; (±)-Camphor-10-sulfonic Acid; 2-Oxo-10-bornanesulfonic Acid; DL-Camphorsulfonic Acid; USP Voriconazole Related Compound F; Voriconazole USP Related Compound F; Voriconazole Related Compound F; 10-Bornanesulfonic acid, 2-oxo-, (±)-; 7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid; Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (±)-; (7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonic acid; (7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonic acid; (7,7-Dimethyl-3-oxoniumylidene-4-bicyclo[2.2.1]heptanyl)methanesulfonate; DL-10-Camphorsulfonic acid
IUPAC Name
(7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methanesulfonic acid
Canonical SMILES
CC1(C2CCC1(C(=O)C2)CS(=O)(=O)O)C
InChI
InChI=1S/C10H16O4S/c1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h7H,3-6H2,1-2H3,(H,12,13,14)
InChI Key
MIOPJNTWMNEORI-UHFFFAOYSA-N
Melting Point
153°C
Flash Point
Not applicable
Purity
98%
Density
1.331±0.06 g/cm3
Solubility
Soluble in Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Ethyl Acetate (Slightly)
Appearance
White to Light Yellow Solid
Application
Used for the resolution of optically active isomers.
Storage
Store at -20°C under inert atmosphere
Vapor Pressure
0.00000007 [mmHg]

Safety Information

Hazards
H314
Precautionary Statement
P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338
Signal Word
Danger

Computed Properties

XLogP3
0.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
232.07693016 g/mol
Monoisotopic Mass
232.07693016 g/mol
Topological Polar Surface Area
79.8Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
404
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
US-11000534-B1 Deuterated derivatives of psilocybin and uses thereof 2020-10-08
US-10988479-B1 Morphic forms of trilaciclib and methods of manufacture thereof 2020-06-15
WO-2021116503-A2 Deuterated compounds 2020-06-02
US-2020360675-A1 Kits for topical,isotonic compositions 2019-12-23
EP-3842060-A1 Stapled lactam co-agonists of the glucagon and glp-1 receptors 2019-12-23
EP-3842061-A1 Stapled triazole co-agonists of the glucagon and glp-1 receptors 2019-12-23
EP-3842449-A1 Stapled olefin co-agonists of the glucagon and glp-1 receptors 2019-12-23
EP-3838345-A1 Macrocyclic peptides 2019-12-20
EP-3838912-A1 Retro-inverso peptides 2019-12-20
US-2021186890-A1 Process of preparing mrna-loaded lipid nanoparticles 2019-12-20

Literatures

PMID Publication Date Title Journal
22744916 2012-10-01 The syntheses of new camphorsulfonylated ligands derived from 2-amino-2'-hydroxy-1,1'-binaphthyl and their enantioselectivities in the addition of dialkylzinc reagents to aldehydes Chirality
22889048 2012-09-07 A novel, facile approach to frondosin B and 5-epi-liphagal via a new [4 + 3]-cycloaddition Organic letters
22548473 2012-05-01 Highly sensitive surface-enhanced Raman spectroscopy (SERS) platforms based on silver nanostructures fabricated on polyaniline membrane surfaces ACS applied materials & interfaces
22302165 2012-04-01 Electrochemically synthesized polymers in molecular imprinting for chemical sensing Analytical and bioanalytical chemistry
22248345 2012-02-23 Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A Journal of medicinal chemistry
22187426 2012-02-17 Characterization of spindle checkpoint kinase Mps1 reveals domain with functional and structural similarities to tetratricopeptide repeat motifs of Bub1 and BubR1 checkpoint kinases The Journal of biological chemistry
22277278 2012-02-15 Camphorsulfonic acid catalysed facile tandem double Friedlander annulation protocol for the synthesis of phenoxy linked bisquinoline derivatives and discovery of antitubercular agents Bioorganic & medicinal chemistry letters
22251083 2012-02-03 Mechanistic variations in ionic hydrogenation of unsaturated phosphine and amine boranes Organic letters
22215085 2012-01-03 Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor Nature communications
21985870 2012-01-01 Electroactive porous tubular scaffolds with degradability and non-cytotoxicity for neural tissue regeneration Acta biomaterialia
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Online Inquiry
  • Verification code
USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Copyright © 2024 BOC Sciences. All rights reserved.
Inquiry Basket