1,2-Bis(3-aminopropylamino)ethane

Product Information

Molecular Formula:
C8H22N4
Molecular Weight:
174.29
Description
1,2-Bis(3-aminopropylamino)ethane (CAS# 10563-26-5) is a useful research chemical.
Synonyms
N'-[2-(3-aminopropylamino)ethyl]propane-1,3-diamine
IUPAC Name
N'-[2-(3-aminopropylamino)ethyl]propane-1,3-diamine
Canonical SMILES
C(CN)CNCCNCCCN
InChI
InChI=1S/C8H22N4/c9-3-1-5-11-7-8-12-6-2-4-10/h11-12H,1-10H2
InChI Key
RXFCIXRFAJRBSG-UHFFFAOYSA-N
Boiling Point
150-160 ℃5 mmHg (lit.)
Melting Point
-1.5 ℃
Flash Point
142 ℃
Purity
95 %
Density
0.952 g/mL at 25℃(lit.)
Appearance
Pale yellow liquid
Application
Used as an intermediate; Used in cleaning agents, as a laboratory reagent, monomer and auxiliary in polymerization reactions, and to make large scale chemicals.
LogP
1.04560

Safety Information

Hazards
H302:
Harmful if swallowed.
H310:
Fatal in contact with skin.
H314:
Causes severe skin burns and eye damage.
Precautionary Statement
P260, P261, P262, P264, P270, P271, P272, P280, P301+P312, P301+P330+P331, P302+P350, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P332+P313, P333+P313, P337+P313, P361, P362, P363, P403+P233, P405, and P501
Signal Word
Danger

Computed Properties

XLogP3
-1.8
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
9
Exact Mass
174.18444672 g/mol
Monoisotopic Mass
174.18444672 g/mol
Topological Polar Surface Area
76.1Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
67.5
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114014819-A Preparation method of 1,4,8, 11-tetraazacyclotetradecane 2021-12-29
CN-114058008-A Process for preparing semi-aromatic polyamides end-capped with monocarboxylic acids, semi-aromatic polyamides and molding compositions 2021-12-13
CN-114058009-A Process for preparing semi-aromatic polyamides with reduced loss of diamine monomer, semi-aromatic polyamides and molding compositions 2021-12-13
CN-114058010-A Process for preparing low-energy semiaromatic polyamides, semiaromatic polyamides and moulding compositions 2021-12-13
CN-114133559-A Process for preparing semiaromatic polyamides with reduced salt formation cycle, semiaromatic polyamides and moulding compositions 2021-12-13
CN-114133560-A Process for preparing semiaromatic polyamides with improved impact strength, semiaromatic polyamides and moulding compositions 2021-12-13
CN-113912514-A Preparation method of aromatic binary secondary amine chain extender 2021-11-15
JP-2022009296-A Resin molded body and decorative sheet 2021-10-20
CN-113801123-A Preparation method of 1,4,8, 11-tetraazacyclotetradecane compound and intermediate thereof 2021-10-18
CN-113956262-A Synthesis method of tetraazacycloalkane compound and intermediate thereof 2021-10-18

Literatures

PMID Publication Date Title Journal
22889556 2012-09-01 Synthesis and in vitro antimalarial activity of a series of bisquinoline and bispyrrolo[1,2a]quinoxaline compounds European journal of medicinal chemistry
21579344 2010-05-26 [2,2'-(2,6,9,13-Tetra-azatetra-decane-1,14-di-yl)diphenolato]iron(III) iodide Acta crystallographica. Section E, Structure reports online
21582074 2009-02-21 Chlorido[2,15-dimethyl-3,7,10,14,20-penta-azabicyclo-[14.3.1]eicosa-1(20),2,14,16,18-penta-ene]manganese(II) perchlorate acetonitrile solvate Acta crystallographica. Section E, Structure reports online
19181267 2009-01-01 Synthesis and biodistribution of lipophilic and monocationic gallium radiopharmaceuticals derived from N,N'-bis(3-aminopropyl)-N,N'-dimethylethylenediamine: potential agents for PET myocardial imaging with 68Ga Nuclear medicine and biology
21201626 2008-08-20 trans-Aqua-(4,7-diaza-decane-1,10-diamine-κN)fluoridochromium(III) bis-(perchlorate) monohydrate Acta crystallographica. Section E, Structure reports online
18497867 2008-01-01 Synthetic polymers as drug-delivery vehicles in medicine Metal-based drugs
16813379 2006-07-10 An S = 2 cyanide-bridged trinuclear Fe(III)2Ni(II) single-molecule magnet Inorganic chemistry
15962942 2005-06-01 Prediction of genotoxicity of chemical compounds by statistical learning methods Chemical research in toxicology
15732975 2005-03-07 A new bimetallic intercalated 3-D assembly magnet [{(323)Ni}3{FeIII(CN)6}2]n x 12nH2O (323 = N,N'-bis(3-aminopropyl) ethylenediamine): an unprecedented concomitant presence of meridional and facial arrangment of ferricyanide anion Inorganic chemistry
15074986 2004-04-19 NMR spectroscopic and X-ray crystallographic study of methylcobalt(III) compounds with saturated amine ligands Inorganic chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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