1,12-Diaminododecane
Product Information
Molecular Formula
C12H28N2
Molecular Weight
200.36
Description
1,12-Diaminododecane (CAS# 2783-17-7) is a long aliphatic diamine that is known to inhibit specific phospholipid-sensitive enzymes and myosin light-chain kinases.
Synonyms
dodecane-1,12-diamine
IUPAC Name
dodecane-1,12-diamine
SMILES
C(CCCCCCN)CCCCCN
InChI
InChI=1S/C12H28N2/c13-11-9-7-5-3-1-2-4-6-8-10-12-14/h1-14H2
InChI Key
QFTYSVGGYOXFRQ-UHFFFAOYSA-N
Boiling Point
304 °C
Melting Point
67-69 °C (lit.)
Flash Point
311 °F
Density
0.856 g/cm3
Appearance
White crystalline solid
Refractive Index
1.4383 (estimate)
LogP
4.20540
Safety Information
Hazards
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H317:
May cause an allergic skin reaction.
H319:
Causes serious eye irritation.
H331:
Toxic if inhaled.
H400:
Very toxic to aquatic life.
Harmful if swallowed.
H315:
Causes skin irritation.
H317:
May cause an allergic skin reaction.
H319:
Causes serious eye irritation.
H331:
Toxic if inhaled.
H400:
Very toxic to aquatic life.
Precautionary Statement
P260, P261, P264, P270, P272, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P332+P313, P333+P313, P362, P363, P405, and P501
Signal Word
Danger
Computed Properties
XLogP3
3
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
11
Exact Mass
200.225248902 g/mol
Monoisotopic Mass
200.225248902 g/mol
Topological Polar Surface Area
52Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
82.3
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114149590-A | Production process of polyether amide elastomer | 2021-12-28 |
| CN-114106716-A | Adhesive interlining suitable for knitted cashmere fabric and preparation method thereof | 2021-12-22 |
| CN-114015011-A | Polyurethane composition and preparation method and application thereof | 2021-12-14 |
| CN-114058008-A | Process for preparing semi-aromatic polyamides end-capped with monocarboxylic acids, semi-aromatic polyamides and molding compositions | 2021-12-13 |
| CN-114058009-A | Process for preparing semi-aromatic polyamides with reduced loss of diamine monomer, semi-aromatic polyamides and molding compositions | 2021-12-13 |
| CN-114058010-A | Process for preparing low-energy semiaromatic polyamides, semiaromatic polyamides and moulding compositions | 2021-12-13 |
| CN-114133559-A | Process for preparing semiaromatic polyamides with reduced salt formation cycle, semiaromatic polyamides and moulding compositions | 2021-12-13 |
| CN-114133560-A | Process for preparing semiaromatic polyamides with improved impact strength, semiaromatic polyamides and moulding compositions | 2021-12-13 |
| CN-114106319-A | Method for continuously preparing polyamide with low gel content and narrow molecular weight distribution and product thereof | 2021-11-18 |
| CN-113896863-A | Epoxy resin glass high polymer material, three-component epoxy solution, preparation method and application | 2021-11-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22802135 | 2012-10-01 | A chemical proteomics approach reveals Hsp27 as a target for proapoptotic clerodane diterpenes | Molecular bioSystems |
| 22907920 | 2012-09-24 | Absolute stereochemical determination of chiral carboxylates using an achiral molecular tweezer | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 22440050 | 2012-06-01 | Diaminododecane-based cationic bolaamphiphile as a non-viral gene delivery carrier | Biomaterials |
| 21907525 | 2011-11-01 | Synthesis, cytotoxicity, and in vitro antileishmanial activity of mono-t-butyloxycarbonyl-protected diamines | Diagnostic microbiology and infectious disease |
| 21190372 | 2011-03-03 | Molecular recognition of melamine by vesicles spontaneously formed from orotic acid derived bolaamphiphiles | The journal of physical chemistry. B |
| 21969739 | 2010-11-01 | Polymers for colon targeted drug delivery | Indian journal of pharmaceutical sciences |
| 20480073 | 2010-06-21 | Unconventional U-shaped conformation of a bolaamphiphile embedded in a synthetic host | Chemical communications (Cambridge, England) |
| 20148228 | 2010-02-27 | Cucurbit[10]uril binding of dinuclear platinum(II) and ruthenium(II) complexes: association/dissociation rates from seconds to hours | Dalton transactions (Cambridge, England : 2003) |
| 19705394 | 2009-10-05 | Guest-directed supramolecular architectures of {W36} polyoxometalate crowns | Chemistry, an Asian journal |
| 19715361 | 2009-09-01 | In situ studies of soft- and reactive landing of mass-selected ions using infrared reflection absorption spectroscopy | Analytical chemistry |
